ES388787A1 - Substituted quinoxaline-di oxides and process of preparation thereof - Google Patents
Substituted quinoxaline-di oxides and process of preparation thereofInfo
- Publication number
- ES388787A1 ES388787A1 ES388787A ES388787A ES388787A1 ES 388787 A1 ES388787 A1 ES 388787A1 ES 388787 A ES388787 A ES 388787A ES 388787 A ES388787 A ES 388787A ES 388787 A1 ES388787 A1 ES 388787A1
- Authority
- ES
- Spain
- Prior art keywords
- formula
- substituted
- acyloxy
- indicated above
- phenyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/36—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems
- C07D241/50—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems with hetero atoms directly attached to ring nitrogen atoms
- C07D241/52—Oxygen atoms
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/10—Organic substances
- A23K20/116—Heterocyclic compounds
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/10—Organic substances
- A23K20/116—Heterocyclic compounds
- A23K20/137—Heterocyclic compounds containing two hetero atoms, of which at least one is nitrogen
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K50/00—Feeding-stuffs specially adapted for particular animals
- A23K50/30—Feeding-stuffs specially adapted for particular animals for swines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
- C07C271/06—Esters of carbamic acids
- C07C271/08—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
- C07C271/10—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C271/16—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of hydrocarbon radicals substituted by singly-bound oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
- C07D263/08—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D263/10—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D263/14—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with radicals substituted by oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/08—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D277/10—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Polymers & Plastics (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Food Science & Technology (AREA)
- Zoology (AREA)
- Animal Husbandry (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Diabetes (AREA)
- Birds (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Abstract
A procedure for preparing new quinoxaline-1,4-dioxides, substituted 2-heterocyclics, of the formula: **(See formula)** where X is a substituent at positions 6 or 7 and is hydrogen, chlorine, bromine, fluoro, methyl, methoxy or trifluoromethyl; Z'is hydroxy; acyloxy of formula -O2CR, where R is hydrogen or alcohol containing 1 to 3 carbon atoms; phenyl, or halogen (F, Cl, Br), phenyl substituted by lower alkoxy or dialkoxylamino or disubstituted amino of the formula NR3R5, where R3 and R5 are each alcohol containing 1 to 2 carbon atoms; A is an alcoholic radical of two to five carbon atoms or is part of a cycloalcohyl group containing from 3 to 8 atoms and where A as part of a cycloalcohyl group, is substituted by hydroxy; and the non-toxic acid addition salts of those compounds, where Z'is disubstituted amino; characterized by (a) reacting, in the presence of a base, a benzofuroxane of the formula: **(See formula)** where X is as indicated above, with a reagent selected from (ii) **(See formula)** where A is as indicated above and Z'is acyloxy, as indicated above, or disubstituted amino; and **(See formula)** where Z'is acyloxy of formula -O2CR where E is as indicated above, phenyl or c-amino-di-substituted phenyl; and when it is necessary to convert compounds of Formula IIA, where Z'is acyloxy, into those where Z' is hydroxy, by acid hydrolysis; and converting the compounds thus obtained in which Z'is di-substituted amino, into non-toxic acid addition salts, by reaction with suitable acids. (Machine-translation by Google Translate, not legally binding)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US2084170A | 1970-03-18 | 1970-03-18 | |
US2084270A | 1970-03-18 | 1970-03-18 |
Publications (1)
Publication Number | Publication Date |
---|---|
ES388787A1 true ES388787A1 (en) | 1974-02-01 |
Family
ID=26693940
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES388787A Expired ES388787A1 (en) | 1970-03-18 | 1971-03-02 | Substituted quinoxaline-di oxides and process of preparation thereof |
Country Status (13)
Country | Link |
---|---|
JP (3) | JPS5434756B1 (en) |
AR (3) | AR202999A1 (en) |
AT (1) | AT315865B (en) |
BE (1) | BE764088A (en) |
CH (1) | CH557356A (en) |
DE (1) | DE2111710C3 (en) |
DK (1) | DK131677C (en) |
ES (1) | ES388787A1 (en) |
FR (1) | FR2085717B1 (en) |
GB (1) | GB1330151A (en) |
IT (1) | IT1019008B (en) |
NL (3) | NL7102953A (en) |
ZA (1) | ZA711022B (en) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3870718A (en) * | 1971-12-13 | 1975-03-11 | Pfizer | 2-imidazolidine substituted quinoxaline-1,4-dioxides and intermediates therefor |
CH575213A5 (en) * | 1972-09-05 | 1976-05-14 | Ciba Geigy Ag | |
US4012512A (en) * | 1972-09-05 | 1977-03-15 | Ciba-Geigy Corporation | Animal feeds containing quinoxaline-di-n-oxide derivatives |
US4254120A (en) * | 1978-12-19 | 1981-03-03 | Ciba-Geigy Corporation | Growth promoting quinoxaline-di-N-oxide carboxamides |
JPS6147989U (en) * | 1984-09-04 | 1986-03-31 | 嶋田機器工業株式会社 | Pressing device for the fabric to be sewn in a sewing machine |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE1058665B (en) * | 1955-10-11 | 1959-06-04 | Gen Aniline & Film Corp | Drying accelerator for film formers containing drying or semi-drying oils |
DE1670935C3 (en) * | 1967-10-04 | 1975-12-04 | Bayer Ag, 5090 Leverkusen | 2-Methyl-3-carboxamidoquinoxaline-1,4-dl-N-oxides, a process for their preparation and antibacterial agents containing these compounds |
-
1970
- 1970-11-03 GB GB5231270A patent/GB1330151A/en not_active Expired
-
1971
- 1971-02-17 ZA ZA711022A patent/ZA711022B/en unknown
- 1971-03-02 ES ES388787A patent/ES388787A1/en not_active Expired
- 1971-03-04 DK DK99971*#A patent/DK131677C/en active
- 1971-03-05 JP JP1136171A patent/JPS5434756B1/ja active Pending
- 1971-03-05 IT IT48832/71A patent/IT1019008B/en active
- 1971-03-05 NL NL7102953A patent/NL7102953A/xx not_active Application Discontinuation
- 1971-03-05 AT AT191571A patent/AT315865B/en not_active IP Right Cessation
- 1971-03-11 BE BE764088A patent/BE764088A/en unknown
- 1971-03-11 DE DE2111710A patent/DE2111710C3/en not_active Expired
- 1971-03-12 FR FR7108799A patent/FR2085717B1/fr not_active Expired
- 1971-03-12 CH CH366771A patent/CH557356A/en not_active IP Right Cessation
- 1971-12-23 AR AR239791A patent/AR202999A1/en active
-
1973
- 1973-01-01 AR AR250155A patent/AR204703A1/en active
- 1973-02-09 AR AR246512A patent/AR197977A1/en active
-
1978
- 1978-04-22 JP JP4831878A patent/JPS53127486A/en active Granted
- 1978-04-22 JP JP4831978A patent/JPS53127487A/en active Granted
- 1978-07-28 NL NL7808008A patent/NL7808008A/en not_active Application Discontinuation
- 1978-07-28 NL NL7808009A patent/NL7808009A/en not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
JPS554749B2 (en) | 1980-01-31 |
JPS53127486A (en) | 1978-11-07 |
NL7102953A (en) | 1971-09-21 |
ZA711022B (en) | 1971-12-29 |
FR2085717A1 (en) | 1971-12-31 |
DE2111710B2 (en) | 1979-01-25 |
NL7808009A (en) | 1978-11-30 |
DK131677C (en) | 1976-04-26 |
GB1330151A (en) | 1973-09-12 |
JPS5434756B1 (en) | 1979-10-29 |
AR197977A1 (en) | 1974-05-24 |
DE2111710A1 (en) | 1971-09-30 |
JPS554748B2 (en) | 1980-01-31 |
IT1019008B (en) | 1977-11-10 |
JPS53127487A (en) | 1978-11-07 |
AR202999A1 (en) | 1975-08-08 |
BE764088A (en) | 1971-09-13 |
AR204703A1 (en) | 1976-02-27 |
NL7808008A (en) | 1978-11-30 |
FR2085717B1 (en) | 1975-06-06 |
AT315865B (en) | 1974-06-10 |
CH557356A (en) | 1974-12-31 |
DK131677B (en) | 1975-08-18 |
DE2111710C3 (en) | 1979-09-13 |
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