ES384512A1 - A method for preparing an oxazolyl derivative. (Machine-translation by Google Translate, not legally binding) - Google Patents
A method for preparing an oxazolyl derivative. (Machine-translation by Google Translate, not legally binding)Info
- Publication number
- ES384512A1 ES384512A1 ES384512A ES384512A ES384512A1 ES 384512 A1 ES384512 A1 ES 384512A1 ES 384512 A ES384512 A ES 384512A ES 384512 A ES384512 A ES 384512A ES 384512 A1 ES384512 A1 ES 384512A1
- Authority
- ES
- Spain
- Prior art keywords
- formula
- group
- see formula
- see
- oxazolyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Landscapes
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Abstract
A method of preparing an oxazolyl derivative having the formula **(See formula)** wherein R1 and R2 each represent a hydrogen atom, an alcohol, cycloalkoxy, or aryl group which may be substituted by alcohol or alkoxy groups or halogen atoms, or R1 and R2 may be linked together to form a cycloalcohyl group and they can be the same or different; B represents a bivalent group; and X represents an oxazolyl group having the formula (II) **(See formula)** where R1 and R2 are the same as identified above, an aryloxazolyl group having the formula (III) **(See formula)** where A represents a benzene or naphthalene nucleus that may be substituted by alcohol groups or halogen atoms or when the bivalent group represented by B is **(See formula)** X represents the oxazolyl group having the formula (II), the aryloxazolyl group having the formula (III), or an aryl group having the formula (IV) **(See formula)** where R3 represents hydrogen or a halogen atom, an alkoxy, cyano, hydroxycarbonyl, alkoxycarbonyl, phenoxycarbonyl group, (see formula) or - NHC0R6 in which each of R4 and R5 represents a hydrogen atom or an alcoholic group and R6 represents an alcoholic or phenyl group, characterized in that it comprises reacting an alpha-aminoketone having the formula **(See formula)** wherein R1 and R2 are as defined above, with an acid halide having the formula **(See formula)** where B and X are as defined above and Hal means a halogen atom, in the presence of a base, and ring-closing the resulting acid amide having the formula **(See formula)** wherein R1, R2, B and X are as defined above in the presence of a dehydrating agent. (Machine-translation by Google Translate, not legally binding)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP8399069 | 1969-10-21 | ||
| JP8746269 | 1969-10-30 | ||
| JP8746169 | 1969-10-30 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES384512A1 true ES384512A1 (en) | 1973-05-01 |
Family
ID=27304394
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES384512A Expired ES384512A1 (en) | 1969-10-21 | 1970-10-14 | A method for preparing an oxazolyl derivative. (Machine-translation by Google Translate, not legally binding) |
Country Status (1)
| Country | Link |
|---|---|
| ES (1) | ES384512A1 (en) |
-
1970
- 1970-10-14 ES ES384512A patent/ES384512A1/en not_active Expired
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