ES381036A1 - Medicamentos analgesicos a base de n-(aroilalkil) n'-(alfa-nols) piperacinas y sus derivados, y procedimiento para su obtencion. - Google Patents
Medicamentos analgesicos a base de n-(aroilalkil) n'-(alfa-nols) piperacinas y sus derivados, y procedimiento para su obtencion.Info
- Publication number
- ES381036A1 ES381036A1 ES381036A ES381036A ES381036A1 ES 381036 A1 ES381036 A1 ES 381036A1 ES 381036 A ES381036 A ES 381036A ES 381036 A ES381036 A ES 381036A ES 381036 A1 ES381036 A1 ES 381036A1
- Authority
- ES
- Spain
- Prior art keywords
- formula
- phenyl group
- compound
- see formula
- procedure
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 238000000034 method Methods 0.000 title abstract 3
- 229940035676 analgesics Drugs 0.000 title abstract 2
- 239000000730 antalgic agent Substances 0.000 title abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 5
- GLUUGHFHXGJENI-UHFFFAOYSA-N Piperazine Chemical compound C1CNCCN1 GLUUGHFHXGJENI-UHFFFAOYSA-N 0.000 abstract 4
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 3
- 229910052739 hydrogen Inorganic materials 0.000 abstract 2
- 239000001257 hydrogen Substances 0.000 abstract 2
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 2
- HTSGKJQDMSTCGS-UHFFFAOYSA-N 1,4-bis(4-chlorophenyl)-2-(4-methylphenyl)sulfonylbutane-1,4-dione Chemical compound C1=CC(C)=CC=C1S(=O)(=O)C(C(=O)C=1C=CC(Cl)=CC=1)CC(=O)C1=CC=C(Cl)C=C1 HTSGKJQDMSTCGS-UHFFFAOYSA-N 0.000 abstract 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 125000004171 alkoxy aryl group Chemical group 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 125000005037 alkyl phenyl group Chemical group 0.000 abstract 1
- 125000006196 aroyl alkyl group Chemical group 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 229910052731 fluorine Inorganic materials 0.000 abstract 1
- 239000011737 fluorine Substances 0.000 abstract 1
- 125000001153 fluoro group Chemical group F* 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 150000002431 hydrogen Chemical group 0.000 abstract 1
- 239000012442 inert solvent Substances 0.000 abstract 1
- 229910052500 inorganic mineral Inorganic materials 0.000 abstract 1
- 239000011707 mineral Substances 0.000 abstract 1
- 150000007522 mineralic acids Chemical class 0.000 abstract 1
- 150000007524 organic acids Chemical class 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/10—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms
- C07D295/104—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms with the ring nitrogen atoms and the doubly bound oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/108—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms with the ring nitrogen atoms and the doubly bound oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR6918171A FR2047866B1 (enrdf_load_stackoverflow) | 1969-06-03 | 1969-06-03 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES381036A1 true ES381036A1 (es) | 1973-04-16 |
Family
ID=9035045
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES381036A Expired ES381036A1 (es) | 1969-06-03 | 1970-06-02 | Medicamentos analgesicos a base de n-(aroilalkil) n'-(alfa-nols) piperacinas y sus derivados, y procedimiento para su obtencion. |
Country Status (8)
| Country | Link |
|---|---|
| BE (1) | BE751351A (enrdf_load_stackoverflow) |
| CH (1) | CH522655A (enrdf_load_stackoverflow) |
| DE (1) | DE2027054A1 (enrdf_load_stackoverflow) |
| ES (1) | ES381036A1 (enrdf_load_stackoverflow) |
| FR (1) | FR2047866B1 (enrdf_load_stackoverflow) |
| GB (1) | GB1289227A (enrdf_load_stackoverflow) |
| LU (1) | LU61040A1 (enrdf_load_stackoverflow) |
| NL (1) | NL7007929A (enrdf_load_stackoverflow) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2145682C3 (de) * | 1971-09-13 | 1975-09-04 | Kali-Chemie Ag, 3000 Hannover | 1,4-disubstituierte Piperazin-Derivate und deren Säureadditionsverbindungen |
| US3969356A (en) * | 1971-09-13 | 1976-07-13 | Kali-Chemie Aktiengesellschaft | N-[3-(p-f-benzoyl)-propyl]-N'-[2.(nitro,nitro-el, or methoxyphenyl)-ethyl]-p |
| FR2206088A1 (en) * | 1972-11-14 | 1974-06-07 | Synthelabo | Analgesic piperazino butyrophenone ketals - prepd. by reaction of halo butyrophenone ketal with hydroxy alkyl piperazine |
| CH591464A5 (enrdf_load_stackoverflow) * | 1973-03-12 | 1977-09-15 | Kali Chemie Ag | |
| CN1181065C (zh) * | 2002-05-08 | 2004-12-22 | 上海医药工业研究院 | 芳烷甲酰烷基哌嗪衍生物及其作为脑神经保护剂的应用 |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1186495A (en) * | 1968-02-20 | 1970-04-02 | Delalande Sa | 0-[3-(4-Fluorobenzoyl) Proplyl]-4-Substituted Piperazines, their Acid Addition Salts and their method of preparation |
-
1969
- 1969-06-03 FR FR6918171A patent/FR2047866B1/fr not_active Expired
-
1970
- 1970-05-29 GB GB1289227D patent/GB1289227A/en not_active Expired
- 1970-06-01 CH CH816770A patent/CH522655A/fr not_active IP Right Cessation
- 1970-06-01 NL NL7007929A patent/NL7007929A/xx unknown
- 1970-06-02 DE DE19702027054 patent/DE2027054A1/de active Pending
- 1970-06-02 ES ES381036A patent/ES381036A1/es not_active Expired
- 1970-06-02 LU LU61040D patent/LU61040A1/xx unknown
- 1970-06-02 BE BE751351D patent/BE751351A/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| DE2027054A1 (de) | 1970-12-10 |
| FR2047866B1 (enrdf_load_stackoverflow) | 1973-03-16 |
| CH522655A (fr) | 1972-06-30 |
| GB1289227A (enrdf_load_stackoverflow) | 1972-09-13 |
| FR2047866A1 (enrdf_load_stackoverflow) | 1971-03-19 |
| NL7007929A (enrdf_load_stackoverflow) | 1970-12-07 |
| LU61040A1 (enrdf_load_stackoverflow) | 1972-03-22 |
| BE751351A (fr) | 1970-12-02 |
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