ES379001A1 - Procedimiento para la obtencion de composiciones a base de soluciones acuosas estables de fosfatos de esteroides. - Google Patents
Procedimiento para la obtencion de composiciones a base de soluciones acuosas estables de fosfatos de esteroides.Info
- Publication number
- ES379001A1 ES379001A1 ES379001A ES379001A ES379001A1 ES 379001 A1 ES379001 A1 ES 379001A1 ES 379001 A ES379001 A ES 379001A ES 379001 A ES379001 A ES 379001A ES 379001 A1 ES379001 A1 ES 379001A1
- Authority
- ES
- Spain
- Prior art keywords
- stable aqueous
- phosphate solutions
- steroid phosphate
- aqueous steroid
- solutions
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 229910019142 PO4 Inorganic materials 0.000 title 1
- 239000010452 phosphate Substances 0.000 title 1
- -1 steroid phosphate Chemical class 0.000 title 1
- CWERGRDVMFNCDR-UHFFFAOYSA-N thioglycolic acid Chemical compound OC(=O)CS CWERGRDVMFNCDR-UHFFFAOYSA-N 0.000 abstract 2
- 239000007864 aqueous solution Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- PJUIMOJAAPLTRJ-UHFFFAOYSA-N monothioglycerol Chemical compound OCC(O)CS PJUIMOJAAPLTRJ-UHFFFAOYSA-N 0.000 abstract 1
- 238000007911 parenteral administration Methods 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 150000003431 steroids Chemical class 0.000 abstract 1
- 229940035024 thioglycerol Drugs 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Steroid Compounds (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT1644669 | 1969-05-07 |
Publications (1)
Publication Number | Publication Date |
---|---|
ES379001A1 true ES379001A1 (es) | 1972-08-01 |
Family
ID=11148881
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES379001A Expired ES379001A1 (es) | 1969-05-07 | 1970-04-24 | Procedimiento para la obtencion de composiciones a base de soluciones acuosas estables de fosfatos de esteroides. |
Country Status (8)
Country | Link |
---|---|
US (1) | US3696195A (es) |
BE (1) | BE750065A (es) |
DE (1) | DE2021446A1 (es) |
ES (1) | ES379001A1 (es) |
FR (1) | FR2051504B1 (es) |
GB (1) | GB1270614A (es) |
IL (1) | IL34366A (es) |
NL (1) | NL142589B (es) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4164570A (en) * | 1973-09-24 | 1979-08-14 | David Clough | Stabilized aqueous catecholamine solutions |
US5173488A (en) * | 1989-08-21 | 1992-12-22 | American Cyanamid Company | Stable injectable pharmaceutical formulation for folic acid and leucovorin salts and method |
DE102009032298A1 (de) | 2009-07-09 | 2011-01-13 | Bergander, Klaus, Dr. | Thiol-funktionalisierte copolymere Polyester durch enzymkatalysierte Veresterungsreaktionen |
EP3189855B1 (en) * | 2016-01-11 | 2018-03-21 | Lamda Laboratories S.A. | Oral pharmaceutical solutions containing hydrocortisone sodium phosphate |
IL301352A (en) * | 2020-09-21 | 2023-05-01 | Antares Pharma Inc | Aqueous pharmaceutical formulation of hydrocortisone sodium phosphate and monothioglycerol |
FR3128874A1 (fr) * | 2021-11-09 | 2023-05-12 | Crossject | Solution pharmaceutique d’hydrocortisone pour dispositif d’injection |
WO2023183807A1 (en) * | 2022-03-21 | 2023-09-28 | Antares Pharma, Inc. | Aqueous pharmaceutical formulation of hydrocortisone sodium phosphate and monothioglycerol |
US11904046B1 (en) | 2022-11-14 | 2024-02-20 | Eton Pharmaceuticals, Inc. | Hydrocortisone oral liquid formulations |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2498200A (en) * | 1948-08-27 | 1950-02-21 | Lilly Co Eli | Stabilized thiamin |
US2719812A (en) * | 1953-08-07 | 1955-10-04 | Merck & Co Inc | Stabilized aqueous solutions of streptomycin |
US3146164A (en) * | 1960-08-09 | 1964-08-25 | Merck & Co Inc | Solutions of steroid phosphate and basic antibiotics stabilized with creatinine |
-
1970
- 1970-04-22 IL IL7034366A patent/IL34366A/xx unknown
- 1970-04-24 ES ES379001A patent/ES379001A1/es not_active Expired
- 1970-05-01 NL NL707006453A patent/NL142589B/xx unknown
- 1970-05-02 DE DE19702021446 patent/DE2021446A1/de not_active Withdrawn
- 1970-05-06 BE BE750065D patent/BE750065A/xx unknown
- 1970-05-06 GB GB21837/70D patent/GB1270614A/en not_active Expired
- 1970-05-06 FR FR707016622A patent/FR2051504B1/fr not_active Expired
- 1970-05-06 US US35236A patent/US3696195A/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
GB1270614A (en) | 1972-04-12 |
FR2051504B1 (es) | 1973-08-10 |
IL34366A (en) | 1973-06-29 |
DE2021446A1 (de) | 1970-11-19 |
NL7006453A (es) | 1970-11-10 |
BE750065A (fr) | 1970-10-16 |
FR2051504A1 (es) | 1971-04-09 |
NL142589B (nl) | 1974-07-15 |
US3696195A (en) | 1972-10-03 |
IL34366A0 (en) | 1970-06-17 |
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