ES378915A1 - Procedure for the preparation of basic beta-tienilderivados. (Machine-translation by Google Translate, not legally binding) - Google Patents

Abstract

Procedure for the preparation of betatienilderivatives of the general formula **(See formula)** in which the thienyl radical can be replaced once or several times by low molecular weight alcohol radicals, the bridge member (see formula) has the structure (see formula) or the structure (see formula) mean hydrogen or low molecular weight alcohol groups, R5 means hydrogen or a hydroxy group, radicals R6 and R7, which are the same or different, mean hydrogen, halogen, hydroxy groups, low molecular weight alcohol groups or groups low molecular weight alkoxy and radicals R8 and R9, which are the same or different, mean hydrogen, hydroxy groups, low molecular weight alcohol groups or low molecular weight alkoxy groups, their optically active or diastereoisomeric forms and their salts, of the general formula, characterized in that, in a manner known per se, a compound of the general formula is reacted **(See formula)** in which X means a thienyl radical- (3) optionally substituted by alcoholic groups or the group (see formula) either with a corresponding phenyl-metallic compound, or with a corresponding thienyl-metallic compound, and eventually the compounds of the general formula I are transformed into (see formula), according to known methods, with water separating agents, in the corresponding unsaturated compounds (see formula), and eventually the basic compounds obtained are transformed, according to known methods, into salts. (Machine-translation by Google Translate, not legally binding)