ES377652A1 - Procedure for the manufacture of alpha-tocopheril-quinona. (Machine-translation by Google Translate, not legally binding) - Google Patents

Procedure for the manufacture of alpha-tocopheril-quinona. (Machine-translation by Google Translate, not legally binding)

Info

Publication number
ES377652A1
ES377652A1 ES377652A ES377652A ES377652A1 ES 377652 A1 ES377652 A1 ES 377652A1 ES 377652 A ES377652 A ES 377652A ES 377652 A ES377652 A ES 377652A ES 377652 A1 ES377652 A1 ES 377652A1
Authority
ES
Spain
Prior art keywords
solvent
alpha
miscible
tocopheril
quinona
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES377652A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Alimentation & Rech Biolog
Original Assignee
Alimentation & Rech Biolog
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alimentation & Rech Biolog filed Critical Alimentation & Rech Biolog
Publication of ES377652A1 publication Critical patent/ES377652A1/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C46/00—Preparation of quinones
    • C07C46/02—Preparation of quinones by oxidation giving rise to quinoid structures
    • C07C46/06—Preparation of quinones by oxidation giving rise to quinoid structures of at least one hydroxy group on a six-membered aromatic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C46/00—Preparation of quinones
    • C07C46/10—Separation; Purification; Stabilisation; Use of additives

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Cosmetics (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrane Compounds (AREA)

Abstract

[alpha]-Tocopherylquinone is obtained by gradually adding a solution of x-toeopherol in a watermiscible solvent to a solution of a mild oxidizing agent in the same or another water-miscible solvent miscible with the first solvent, whilst stirring at room temperature, and when the reaction is complete diluting with excess water and extracting the x-toeopherylquinone with a solvent which is not miscible with water and in which the product has a higher solubility than in the solvents for the reactants. In examples, the oxidizing agent is ferric nitrate, the reaction solvents are ethyl alcohol and methyl alcohol and the product is extracted with ethyl ether and with methylene chloride.
ES377652A 1969-04-24 1970-03-18 Procedure for the manufacture of alpha-tocopheril-quinona. (Machine-translation by Google Translate, not legally binding) Expired ES377652A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR6911683A FR2040859A5 (en) 1969-04-24 1969-04-24

Publications (1)

Publication Number Publication Date
ES377652A1 true ES377652A1 (en) 1973-02-01

Family

ID=9032449

Family Applications (1)

Application Number Title Priority Date Filing Date
ES377652A Expired ES377652A1 (en) 1969-04-24 1970-03-18 Procedure for the manufacture of alpha-tocopheril-quinona. (Machine-translation by Google Translate, not legally binding)

Country Status (8)

Country Link
BE (1) BE746160A (en)
CH (1) CH511226A (en)
ES (1) ES377652A1 (en)
FR (1) FR2040859A5 (en)
GB (1) GB1251472A (en)
IT (1) IT1034014B (en)
LU (1) LU60457A1 (en)
NL (1) NL7005984A (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20110263720A1 (en) * 2010-03-09 2011-10-27 Penwest Pharmaceuticals Co. Synthesis of alpha-tocopherolquinone derivatives, and methods of using the same

Also Published As

Publication number Publication date
IT1034014B (en) 1979-09-10
BE746160A (en) 1970-07-31
GB1251472A (en) 1971-10-27
FR2040859A5 (en) 1971-01-22
NL7005984A (en) 1970-10-27
CH511226A (en) 1971-08-15
LU60457A1 (en) 1970-05-04
DE2007763A1 (en) 1971-03-11

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