ES375023A1 - Procedimiento para la obtencion de derivados del acido tia-zolidina carboxilico. - Google Patents
Procedimiento para la obtencion de derivados del acido tia-zolidina carboxilico.Info
- Publication number
- ES375023A1 ES375023A1 ES375023A ES375023A ES375023A1 ES 375023 A1 ES375023 A1 ES 375023A1 ES 375023 A ES375023 A ES 375023A ES 375023 A ES375023 A ES 375023A ES 375023 A1 ES375023 A1 ES 375023A1
- Authority
- ES
- Spain
- Prior art keywords
- cyclic
- formula
- heterocyclic
- substituted
- radical
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- DZLNHFMRPBPULJ-VKHMYHEASA-N L-thioproline Chemical compound OC(=O)[C@@H]1CSCN1 DZLNHFMRPBPULJ-VKHMYHEASA-N 0.000 title abstract 2
- 239000003814 drug Substances 0.000 title 1
- 125000004122 cyclic group Chemical group 0.000 abstract 4
- 239000002253 acid Substances 0.000 abstract 3
- 125000000623 heterocyclic group Chemical group 0.000 abstract 3
- QGZKDVFQNNGYKY-UHFFFAOYSA-N Ammonia Chemical compound N QGZKDVFQNNGYKY-UHFFFAOYSA-N 0.000 abstract 2
- YNAVUWVOSKDBBP-UHFFFAOYSA-N Morpholine Chemical compound C1COCCN1 YNAVUWVOSKDBBP-UHFFFAOYSA-N 0.000 abstract 2
- 125000003545 alkoxy group Chemical group 0.000 abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 125000003118 aryl group Chemical group 0.000 abstract 2
- 125000004104 aryloxy group Chemical group 0.000 abstract 2
- 229910052739 hydrogen Inorganic materials 0.000 abstract 2
- 239000001257 hydrogen Substances 0.000 abstract 2
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 2
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 2
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 1
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical compound [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 abstract 1
- 150000001408 amides Chemical class 0.000 abstract 1
- 229910021529 ammonia Inorganic materials 0.000 abstract 1
- 230000000954 anitussive effect Effects 0.000 abstract 1
- 229940124584 antitussives Drugs 0.000 abstract 1
- 150000001732 carboxylic acid derivatives Chemical class 0.000 abstract 1
- PCHPORCSPXIHLZ-UHFFFAOYSA-N diphenhydramine hydrochloride Chemical compound [Cl-].C=1C=CC=CC=1C(OCC[NH+](C)C)C1=CC=CC=C1 PCHPORCSPXIHLZ-UHFFFAOYSA-N 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
- 125000002485 formyl group Chemical class [H]C(*)=O 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 230000000510 mucolytic effect Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 229910052717 sulfur Inorganic materials 0.000 abstract 1
- 239000011593 sulfur Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/04—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D277/06—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR182571A FR8266M (enrdf_load_stackoverflow) | 1968-12-31 | 1968-12-31 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES375023A1 true ES375023A1 (es) | 1972-03-01 |
Family
ID=8659685
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES375023A Expired ES375023A1 (es) | 1968-12-31 | 1969-12-30 | Procedimiento para la obtencion de derivados del acido tia-zolidina carboxilico. |
Country Status (7)
| Country | Link |
|---|---|
| BE (1) | BE743905A (enrdf_load_stackoverflow) |
| CA (1) | CA959850A (enrdf_load_stackoverflow) |
| CH (1) | CH511248A (enrdf_load_stackoverflow) |
| DE (1) | DE1965343A1 (enrdf_load_stackoverflow) |
| ES (1) | ES375023A1 (enrdf_load_stackoverflow) |
| FR (1) | FR8266M (enrdf_load_stackoverflow) |
| GB (1) | GB1299201A (enrdf_load_stackoverflow) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3592905A (en) * | 1969-10-30 | 1971-07-13 | Merck & Co Inc | Therapeutic methods |
| FR2222087B1 (enrdf_load_stackoverflow) * | 1973-03-22 | 1976-04-09 | Ferlux | |
| IT1190945B (it) * | 1982-08-06 | 1988-02-24 | Salus Research Sarm Spa | Composto ad azione broncosegretogoga,fluidificante ed antitussigena,procedimento per la sua preparazione e composizioni farmaceutiche che lo contengono |
| DE3376341D1 (en) * | 1982-08-09 | 1988-05-26 | Ajinomoto Kk | Method for producing 2-substituted-thiazolidine-4-carboxylic acids |
| HU195492B (en) * | 1984-07-27 | 1988-05-30 | Boehringer Biochemia Srl | Process for producing 2-substituted thiazolidine derivatives with antitussive and mucus regulating action and pharmaceuticals comprising these compounds as active ingredient |
| EP0348541B1 (en) * | 1988-06-29 | 1992-04-01 | YASON S.r.l | N-carbethoxy-4-thiazolidine-carboxylic acid, process for its preparation and its use as medicament |
-
1968
- 1968-12-31 FR FR182571A patent/FR8266M/fr not_active Expired
-
1969
- 1969-07-30 CH CH1157869A patent/CH511248A/fr not_active IP Right Cessation
- 1969-12-29 DE DE19691965343 patent/DE1965343A1/de active Pending
- 1969-12-30 BE BE743905D patent/BE743905A/xx unknown
- 1969-12-30 CA CA071,114A patent/CA959850A/en not_active Expired
- 1969-12-30 ES ES375023A patent/ES375023A1/es not_active Expired
- 1969-12-31 GB GB63488/69A patent/GB1299201A/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| CH511248A (fr) | 1971-08-15 |
| DE1965343A1 (de) | 1970-07-23 |
| CA959850A (en) | 1974-12-24 |
| FR8266M (enrdf_load_stackoverflow) | 1970-10-26 |
| BE743905A (enrdf_load_stackoverflow) | 1970-05-28 |
| GB1299201A (en) | 1972-12-13 |
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