ES367241A1 - Method of preparing purified golagenase that is essentially exempt from proteolic and elastolitic activity. (Machine-translation by Google Translate, not legally binding) - Google Patents

Method of preparing purified golagenase that is essentially exempt from proteolic and elastolitic activity. (Machine-translation by Google Translate, not legally binding)

Info

Publication number
ES367241A1
ES367241A1 ES367241A ES367241A ES367241A1 ES 367241 A1 ES367241 A1 ES 367241A1 ES 367241 A ES367241 A ES 367241A ES 367241 A ES367241 A ES 367241A ES 367241 A1 ES367241 A1 ES 367241A1
Authority
ES
Spain
Prior art keywords
activity
proteolic
golagenase
elastolitic
translation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES367241A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Worthington Biochemical Corp
Original Assignee
Worthington Biochemical Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Worthington Biochemical Corp filed Critical Worthington Biochemical Corp
Publication of ES367241A1 publication Critical patent/ES367241A1/en
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/488—Aspartic endopeptidases (3.4.23), e.g. pepsin, chymosin, renin, cathepsin E

Abstract

A pharmaceutical composition for intervertebral injection in the treatment of herniated intervertebral disc comprises, in a sealed vial, a measured dosage of lyophilized sterile collagenase substantially free of proteolytic or elastolytic activity in an amount appropriate for a single injection. The collagenase may be dissolved in an aqueous solvent which may comprise a pharmaceutically acceptable (e.g. phosphate or sodium chloride) buffer.
ES367241A 1968-05-15 1969-05-14 Method of preparing purified golagenase that is essentially exempt from proteolic and elastolitic activity. (Machine-translation by Google Translate, not legally binding) Expired ES367241A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US72943668A 1968-05-15 1968-05-15

Publications (1)

Publication Number Publication Date
ES367241A1 true ES367241A1 (en) 1971-07-16

Family

ID=24931011

Family Applications (1)

Application Number Title Priority Date Filing Date
ES367241A Expired ES367241A1 (en) 1968-05-15 1969-05-14 Method of preparing purified golagenase that is essentially exempt from proteolic and elastolitic activity. (Machine-translation by Google Translate, not legally binding)

Country Status (5)

Country Link
JP (1) JPS4824229B1 (en)
DE (1) DE1924715C3 (en)
ES (1) ES367241A1 (en)
FR (1) FR2008611A1 (en)
GB (1) GB1251398A (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS56154828U (en) * 1980-04-21 1981-11-19
JPS5894315U (en) * 1981-12-22 1983-06-27 株式会社クボタ rice transplanter
JPS5894314U (en) * 1981-12-22 1983-06-27 株式会社クボタ rice transplanter
WO1987000860A1 (en) * 1985-08-10 1987-02-12 Biopharm (Uk) Limited Collagen-specific enzyme with platelet aggregation inhibition properties
US5173295A (en) * 1990-10-05 1992-12-22 Advance Biofactures Of Curacao, N.V. Method of enhancing the regeneration of injured nerves and adhesive pharamaceutical formulation therefor
AU5126596A (en) * 1995-04-07 1996-10-23 Rijksuniversiteit Leiden Use of gelatinase b and related enzymes to mobilize hematopo ietic stem cells for blood stem cell transplantation

Also Published As

Publication number Publication date
DE1924715C3 (en) 1974-04-25
GB1251398A (en) 1971-10-27
FR2008611A1 (en) 1970-01-23
DE1924715B2 (en) 1973-09-27
DE1924715A1 (en) 1969-11-27
JPS4824229B1 (en) 1973-07-19

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