ES362305A1 - Procedimiento para la produccion de 4-fenilimino - 1,4 - dihidroquinolinas. - Google Patents
Procedimiento para la produccion de 4-fenilimino - 1,4 - dihidroquinolinas.Info
- Publication number
- ES362305A1 ES362305A1 ES362305A ES362305A ES362305A1 ES 362305 A1 ES362305 A1 ES 362305A1 ES 362305 A ES362305 A ES 362305A ES 362305 A ES362305 A ES 362305A ES 362305 A1 ES362305 A1 ES 362305A1
- Authority
- ES
- Spain
- Prior art keywords
- alkyl
- aryl
- halogen
- formula
- prepared
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 238000004519 manufacturing process Methods 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 10
- 125000003118 aryl group Chemical group 0.000 abstract 4
- 150000001875 compounds Chemical class 0.000 abstract 4
- 229910052736 halogen Inorganic materials 0.000 abstract 4
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 3
- 150000003839 salts Chemical class 0.000 abstract 3
- 239000002253 acid Substances 0.000 abstract 2
- 125000003545 alkoxy group Chemical group 0.000 abstract 2
- 125000005843 halogen group Chemical group 0.000 abstract 2
- 150000002367 halogens Chemical class 0.000 abstract 2
- 230000007062 hydrolysis Effects 0.000 abstract 2
- 238000006460 hydrolysis reaction Methods 0.000 abstract 2
- 125000006555 (C3-C5) cycloalkyl group Chemical group 0.000 abstract 1
- QAOWNCQODCNURD-UHFFFAOYSA-L Sulfate Chemical group [O-]S([O-])(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-L 0.000 abstract 1
- 150000007513 acids Chemical class 0.000 abstract 1
- 125000005530 alkylenedioxy group Chemical group 0.000 abstract 1
- 230000001760 anti-analgesic effect Effects 0.000 abstract 1
- 230000003110 anti-inflammatory effect Effects 0.000 abstract 1
- 230000000078 anti-malarial effect Effects 0.000 abstract 1
- 230000001754 anti-pyretic effect Effects 0.000 abstract 1
- 239000003430 antimalarial agent Substances 0.000 abstract 1
- 239000002221 antipyretic Substances 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 238000006243 chemical reaction Methods 0.000 abstract 1
- 230000005494 condensation Effects 0.000 abstract 1
- 238000009833 condensation Methods 0.000 abstract 1
- 230000032050 esterification Effects 0.000 abstract 1
- 238000005886 esterification reaction Methods 0.000 abstract 1
- 239000000543 intermediate Substances 0.000 abstract 1
- 150000002828 nitro derivatives Chemical class 0.000 abstract 1
- 238000007911 parenteral administration Methods 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 125000000951 phenoxy group Chemical group [H]C1=C([H])C([H])=C(O*)C([H])=C1[H] 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 229910021653 sulphate ion Inorganic materials 0.000 abstract 1
- -1 tetrahydropyranyloxy Chemical group 0.000 abstract 1
- JOXIMZWYDAKGHI-UHFFFAOYSA-M toluene-4-sulfonate Chemical group CC1=CC=C(S([O-])(=O)=O)C=C1 JOXIMZWYDAKGHI-UHFFFAOYSA-M 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/38—Nitrogen atoms
- C07D215/42—Nitrogen atoms attached in position 4
- C07D215/44—Nitrogen atoms attached in position 4 with aryl radicals attached to said nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
- C07C205/49—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups
- C07C205/56—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups having nitro groups bound to carbon atoms of six-membered aromatic rings and carboxyl groups bound to acyclic carbon atoms of the carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/58—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems with hetero atoms directly attached to the ring nitrogen atom
- C07D215/60—N-oxides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/10—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
- C07D317/14—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D317/18—Radicals substituted by singly bound oxygen or sulfur atoms
- C07D317/24—Radicals substituted by singly bound oxygen or sulfur atoms esterified
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US69441167A | 1967-12-29 | 1967-12-29 | |
| ZA687889 | 1968-12-02 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES362305A1 true ES362305A1 (es) | 1972-04-16 |
Family
ID=27105373
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES362305A Expired ES362305A1 (es) | 1967-12-29 | 1968-12-27 | Procedimiento para la produccion de 4-fenilimino - 1,4 - dihidroquinolinas. |
Country Status (9)
| Country | Link |
|---|---|
| AT (1) | AT287719B (en(2012)) |
| BE (1) | BE726093A (en(2012)) |
| CH (1) | CH506526A (en(2012)) |
| ES (1) | ES362305A1 (en(2012)) |
| FR (2) | FR1601535A (en(2012)) |
| GB (1) | GB1258920A (en(2012)) |
| IL (1) | IL31341A0 (en(2012)) |
| NL (1) | NL6818444A (en(2012)) |
| SE (1) | SE339688B (en(2012)) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2001047888A1 (fr) * | 1999-12-28 | 2001-07-05 | Nissan Chemical Industries, Ltd. | Composes imino heterocycliques, fongicides et insecticides a usage agricole et horticole |
| WO2008048577A1 (en) * | 2006-10-17 | 2008-04-24 | Milestone Pharmaceuticals Inc. | Methods of using 4-phenylaminoquinolines as topical non-steroidal antiinflammatory compounds |
-
1968
- 1968-12-20 NL NL6818444A patent/NL6818444A/xx unknown
- 1968-12-20 SE SE17566/68A patent/SE339688B/xx unknown
- 1968-12-24 CH CH1924868A patent/CH506526A/de not_active IP Right Cessation
- 1968-12-27 BE BE726093D patent/BE726093A/xx unknown
- 1968-12-27 IL IL31341A patent/IL31341A0/xx unknown
- 1968-12-27 ES ES362305A patent/ES362305A1/es not_active Expired
- 1968-12-27 FR FR1601535D patent/FR1601535A/fr not_active Expired
- 1968-12-27 AT AT1259468A patent/AT287719B/de not_active IP Right Cessation
- 1968-12-30 GB GB1258920D patent/GB1258920A/en not_active Expired
-
1969
- 1969-03-26 FR FR183301A patent/FR8283M/fr not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| SE339688B (en(2012)) | 1971-10-18 |
| FR1601535A (en(2012)) | 1970-08-24 |
| IL31341A0 (en) | 1969-02-27 |
| GB1258920A (en(2012)) | 1971-12-30 |
| AT287719B (de) | 1971-02-10 |
| DE1816700A1 (de) | 1969-12-04 |
| CH506526A (de) | 1971-04-30 |
| FR8283M (en(2012)) | 1970-11-02 |
| NL6818444A (en(2012)) | 1969-07-01 |
| BE726093A (en(2012)) | 1969-06-27 |
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