ES359268A1 - Un procedimiento para la preparacion de 6 alfa, 6 beta-di- fluoresteroides. - Google Patents
Un procedimiento para la preparacion de 6 alfa, 6 beta-di- fluoresteroides.Info
- Publication number
- ES359268A1 ES359268A1 ES359268A ES359268A ES359268A1 ES 359268 A1 ES359268 A1 ES 359268A1 ES 359268 A ES359268 A ES 359268A ES 359268 A ES359268 A ES 359268A ES 359268 A1 ES359268 A1 ES 359268A1
- Authority
- ES
- Spain
- Prior art keywords
- alpha
- alkyl
- monocyclic
- compounds
- formula
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
- A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J75/00—Processes for the preparation of steroids in general
-
- G—PHYSICS
- G12—INSTRUMENT DETAILS
- G12B—CONSTRUCTIONAL DETAILS OF INSTRUMENTS, OR COMPARABLE DETAILS OF OTHER APPARATUS, NOT OTHERWISE PROVIDED FOR
- G12B13/00—Calibrating of instruments and apparatus
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Steroid Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US67606067A | 1967-10-18 | 1967-10-18 | |
US76391868A | 1968-09-30 | 1968-09-30 |
Publications (1)
Publication Number | Publication Date |
---|---|
ES359268A1 true ES359268A1 (es) | 1970-06-01 |
Family
ID=27101468
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES359268A Expired ES359268A1 (es) | 1967-10-18 | 1968-10-17 | Un procedimiento para la preparacion de 6 alfa, 6 beta-di- fluoresteroides. |
Country Status (6)
Country | Link |
---|---|
US (1) | US3546215A (es) |
CH (1) | CH526524A (es) |
ES (1) | ES359268A1 (es) |
GB (1) | GB1248938A (es) |
HK (1) | HK70376A (es) |
NL (1) | NL160722C (es) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FI46952C (fi) * | 1969-03-11 | 1973-08-10 | Schering Ag | Menetelmä 6alfa-fluori-9alfa,11beta,21-trihalogeeni-1,4-pregnadieeni-3 ,20-dioni-johdannaisten valmistamiseksi |
CH513843A (fr) * | 1969-04-23 | 1971-10-15 | Lark Spa | Procédé d'oxhydrilation microbiologique en position 11B |
IL36428A (en) * | 1970-04-22 | 1975-05-22 | Du Pont | 6,6-difluoro-pregna-3,20-dione derivatives,their preparation and pharmaceutical compositions containing them |
US3716529A (en) * | 1970-05-14 | 1973-02-13 | Syntex Corp | Novel c-16,17 spiro-orthoester steroids and preparation |
US3718673A (en) * | 1971-02-01 | 1973-02-27 | Du Pont | Process for the preparation of 21-chloro-6,6,9alpha-trifluoro-11beta, alpha, 17alpha-trihydroxy-1,4-pregnadien-3,20-dione 16,17-ketals and selected intermediates |
US4198404A (en) * | 1978-04-05 | 1980-04-15 | Syntex (U.S.A.) Inc. | 6 Alpha, 6 beta-difluoro-etianic acid derivatives |
US4588718A (en) * | 1984-03-28 | 1986-05-13 | The Upjohn Company | Carboxy containing ester prodrugs of corticosteroids |
US4948533A (en) * | 1984-03-28 | 1990-08-14 | The Upjohn Company | 11a-hydroxy steroid diester |
EP0523132A1 (en) * | 1990-03-27 | 1993-01-20 | Schering Corporation | PROCESS FOR 9$g(a)-HYDROXY STEROID DEHYDRATION |
FR2701262B1 (fr) * | 1993-02-05 | 1995-03-24 | Roussel Uclaf | Nouveau procédé de préparation de stéroïdes 6 alpa, 9 alpha-difluorés et nouveaus intermédiaires. |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3264332A (en) * | 1959-01-07 | 1966-08-02 | Schering Corp | 6-halogeno-1, 4, 6-pregnatrienes and the 1, 2-dihydro analogs thereof |
US3282969A (en) * | 1964-07-02 | 1966-11-01 | Du Pont | 7, 7-gem-difluoro steroids of the androstane and pregnane series |
-
1968
- 1968-09-30 US US3546215D patent/US3546215A/en not_active Expired - Lifetime
- 1968-10-17 GB GB4923268A patent/GB1248938A/en not_active Expired
- 1968-10-17 NL NL6814846A patent/NL160722C/xx active
- 1968-10-17 ES ES359268A patent/ES359268A1/es not_active Expired
- 1968-10-18 CH CH1562568A patent/CH526524A/de not_active IP Right Cessation
-
1976
- 1976-11-11 HK HK70376A patent/HK70376A/xx unknown
Also Published As
Publication number | Publication date |
---|---|
NL160722B (nl) | 1979-07-16 |
GB1248938A (en) | 1971-10-06 |
NL6814846A (es) | 1969-04-22 |
HK70376A (en) | 1976-11-19 |
CH526524A (de) | 1972-08-15 |
DE1802962B2 (de) | 1975-12-04 |
US3546215A (en) | 1970-12-08 |
DE1802962A1 (de) | 1969-05-08 |
NL160722C (nl) | 1979-12-17 |
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