ES356776A2 - Isoindolino-sulphonylurea compounds - Google Patents
Isoindolino-sulphonylurea compoundsInfo
- Publication number
- ES356776A2 ES356776A2 ES356776A ES356776A ES356776A2 ES 356776 A2 ES356776 A2 ES 356776A2 ES 356776 A ES356776 A ES 356776A ES 356776 A ES356776 A ES 356776A ES 356776 A2 ES356776 A2 ES 356776A2
- Authority
- ES
- Spain
- Prior art keywords
- formula
- isoindolino
- benzamidoethyl
- methoxy
- compounds
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/44—Iso-indoles; Hydrogenated iso-indoles
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Indole Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Novel compounds of the formula wherein X represents H or Cl, are obtained by reacting an arylsulphonyl-ethyl urethane of general formula with an N-amino-isoindoline. N - [4 - (# - o - methoxy - benzamidoethyl)benzenesulphonyl]ethylurethane is obtained from N- [4 - (# - o - methoxy - benzamidoethyl)] benzene sulphamide and ethyl chloroformate. Pharmaceutical compositions, useful in the treatment of diabetes, comprise compounds of Formula I in admixture with a pharmaceutically suitable carrier, in forms suitable for oral, rectal or parenteral administration.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB29841/65A GB1146979A (en) | 1965-07-14 | 1965-07-14 | New isoindolino-sulphonylurea derivatives and process for preparing them |
GB36807/67A GB1193289A (en) | 1965-07-14 | 1967-08-10 | New Isoindolino-Sulphonylurea Derivatives and Process for Preparing them |
Publications (1)
Publication Number | Publication Date |
---|---|
ES356776A2 true ES356776A2 (en) | 1970-02-01 |
Family
ID=26260110
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES356776A Expired ES356776A2 (en) | 1965-07-14 | 1968-08-01 | Isoindolino-sulphonylurea compounds |
Country Status (9)
Country | Link |
---|---|
US (1) | US3535335A (en) |
AT (1) | AT278847B (en) |
BE (1) | BE718257A (en) |
BR (1) | BR6801368D0 (en) |
CH (1) | CH496693A (en) |
DE (1) | DE1770915A1 (en) |
ES (1) | ES356776A2 (en) |
FR (2) | FR95283E (en) |
GB (1) | GB1193289A (en) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IT1113879B (en) * | 1979-03-15 | 1986-01-27 | Farmatis Spa | ISOINDOLINE DERIVATIVE, PROCESS FOR ITS PREPARATION AND THERAPEUTIC COMPOSITIONS THAT INCLUDE IT AS AN ACTIVE PRINCIPLE |
NZ597500A (en) * | 2003-08-06 | 2014-08-29 | Senomyx Inc | Novel flavors, flavor modifiers, tastants, taste enhancers, umami or sweet tastants, and/or enhancers and use thereof |
US20060045953A1 (en) * | 2004-08-06 | 2006-03-02 | Catherine Tachdjian | Aromatic amides and ureas and their uses as sweet and/or umami flavor modifiers, tastants and taste enhancers |
EP1855548A2 (en) * | 2005-02-04 | 2007-11-21 | Senomyx, Inc. | Molecules comprising linked organic moieties as flavor modifiers for comestibles compositions |
RU2410383C2 (en) | 2005-02-04 | 2011-01-27 | Синомикс, Инк. | Compounds having bound heteroaryl fragments and use thereof as novel umami taste modifiers, tastants (taste bud cell stimulants) and taste boosters in food compositions |
TW200715993A (en) * | 2005-06-15 | 2007-05-01 | Senomyx Inc | Bis-aromatic amides and their uses as sweet flavor modifiers, tastants, and taste enhancers |
WO2007124152A2 (en) | 2006-04-21 | 2007-11-01 | Senomyx, Inc. | Comestible compositions comprising high potency savory flavorants, and processes for producing them |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE1670770C3 (en) * | 1966-11-16 | 1974-10-17 | Bayer Ag, 5090 Leverkusen | Arylsulfonylureas and arylsulfonylthioureas |
-
1967
- 1967-08-10 GB GB36807/67A patent/GB1193289A/en not_active Expired
-
1968
- 1968-07-18 BE BE718257D patent/BE718257A/xx unknown
- 1968-07-19 DE DE19681770915 patent/DE1770915A1/en active Pending
- 1968-07-30 US US748628A patent/US3535335A/en not_active Expired - Lifetime
- 1968-07-30 AT AT740868A patent/AT278847B/en not_active IP Right Cessation
- 1968-08-01 FR FR161472A patent/FR95283E/en not_active Expired
- 1968-08-01 ES ES356776A patent/ES356776A2/en not_active Expired
- 1968-08-02 CH CH1159768A patent/CH496693A/en unknown
- 1968-08-09 BR BR201368/68A patent/BR6801368D0/en unknown
- 1968-10-30 FR FR342D patent/FR342F/fr not_active Expired
Also Published As
Publication number | Publication date |
---|---|
BE718257A (en) | 1969-01-20 |
BR6801368D0 (en) | 1973-02-22 |
AT278847B (en) | 1970-02-10 |
CH496693A (en) | 1970-09-30 |
FR95283E (en) | 1970-08-14 |
FR342F (en) | 1971-01-11 |
US3535335A (en) | 1970-10-20 |
GB1193289A (en) | 1970-05-28 |
DE1770915A1 (en) | 1972-02-24 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FD2A | Announcement of lapse in spain |
Effective date: 20170630 |