ES347802A1 - Procedure for the preparation of benzodiacepine derivatives. (Machine-translation by Google Translate, not legally binding) - Google Patents

Procedure for the preparation of benzodiacepine derivatives. (Machine-translation by Google Translate, not legally binding)

Info

Publication number
ES347802A1
ES347802A1 ES347802A ES347802A ES347802A1 ES 347802 A1 ES347802 A1 ES 347802A1 ES 347802 A ES347802 A ES 347802A ES 347802 A ES347802 A ES 347802A ES 347802 A1 ES347802 A1 ES 347802A1
Authority
ES
Spain
Prior art keywords
translation
procedure
preparation
machine
lower alkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES347802A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Publication of ES347802A1 publication Critical patent/ES347802A1/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/14—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • C07D243/16—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
    • C07D243/18—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
    • C07D243/24—Oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/14—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • C07D243/16—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
    • C07D243/18—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
    • C07D243/20—Nitrogen atoms

Abstract

A procedure for the preparation of benzodiazepine derivatives of the formula **(See formula)** where A represents the group **(See formula)** R1 represents hydrogen, halogen or trifluoromethyl; R2 represents hydrogen or lower alkyl; R3 represents hydrogen, lower alkyl, and lower alkenyl; R4 represents hydrogen or lower alkyl; and R5 represents hydrogen, halogen or lower alkyl, characterized by being a compound of the formula **(See formula)** where A, R1 and R2 have the same meaning that has been attributed to them before, with a phenyl metalloorganic compound, a phenyl metalloorganic compound substituted by lower alkyl or a phenyl metalloorganic compound substituted by halogen. (Machine-translation by Google Translate, not legally binding)
ES347802A 1966-12-01 1967-11-30 Procedure for the preparation of benzodiacepine derivatives. (Machine-translation by Google Translate, not legally binding) Expired ES347802A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US59820166A 1966-12-01 1966-12-01

Publications (1)

Publication Number Publication Date
ES347802A1 true ES347802A1 (en) 1969-02-16

Family

ID=24394635

Family Applications (1)

Application Number Title Priority Date Filing Date
ES347802A Expired ES347802A1 (en) 1966-12-01 1967-11-30 Procedure for the preparation of benzodiacepine derivatives. (Machine-translation by Google Translate, not legally binding)

Country Status (6)

Country Link
AT (1) AT277252B (en)
CH (1) CH507965A (en)
ES (1) ES347802A1 (en)
GR (1) GR37780B (en)
NL (1) NL6716384A (en)
YU (1) YU34200B (en)

Also Published As

Publication number Publication date
CH507965A (en) 1971-05-31
YU235867A (en) 1978-06-30
YU34200B (en) 1979-02-28
NL6716384A (en) 1968-06-04
AT277252B (en) 1969-12-29
GR37780B (en) 1969-07-14

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