ES338641A1 - Procedimiento para la obtencion de un compuesto analgesico y antiinflamatorio. - Google Patents
Procedimiento para la obtencion de un compuesto analgesico y antiinflamatorio.Info
- Publication number
- ES338641A1 ES338641A1 ES338641A ES338641A ES338641A1 ES 338641 A1 ES338641 A1 ES 338641A1 ES 338641 A ES338641 A ES 338641A ES 338641 A ES338641 A ES 338641A ES 338641 A1 ES338641 A1 ES 338641A1
- Authority
- ES
- Spain
- Prior art keywords
- indole
- piperazinomethyl
- fluoro
- phenyl
- compositions containing
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- PCLWAFVRAWUFRN-UHFFFAOYSA-N 3-[[4-(4-fluorophenyl)piperazin-1-yl]methyl]-1h-indole Chemical compound C1=CC(F)=CC=C1N1CCN(CC=2C3=CC=CC=C3NC=2)CC1 PCLWAFVRAWUFRN-UHFFFAOYSA-N 0.000 title abstract 2
- 239000000203 mixture Substances 0.000 title abstract 2
- 230000001225 therapeutic effect Effects 0.000 title 1
- WSFSSNUMVMOOMR-UHFFFAOYSA-N Formaldehyde Chemical compound O=C WSFSSNUMVMOOMR-UHFFFAOYSA-N 0.000 abstract 3
- SIKJAQJRHWYJAI-UHFFFAOYSA-N Indole Chemical compound C1=CC=C2NC=CC2=C1 SIKJAQJRHWYJAI-UHFFFAOYSA-N 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- AVJKDKWRVSSJPK-UHFFFAOYSA-N 1-(4-fluorophenyl)piperazine Chemical compound C1=CC(F)=CC=C1N1CCNCC1 AVJKDKWRVSSJPK-UHFFFAOYSA-N 0.000 abstract 1
- 230000000202 analgesic effect Effects 0.000 abstract 1
- 239000007891 compressed tablet Substances 0.000 abstract 1
- PZOUSPYUWWUPPK-UHFFFAOYSA-N indole Natural products CC1=CC=CC2=C1C=CN2 PZOUSPYUWWUPPK-UHFFFAOYSA-N 0.000 abstract 1
- RKJUIXBNRJVNHR-UHFFFAOYSA-N indolenine Natural products C1=CC=C2CC=NC2=C1 RKJUIXBNRJVNHR-UHFFFAOYSA-N 0.000 abstract 1
- 239000013067 intermediate product Substances 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 239000000829 suppository Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Indole Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| MC617A MC614A1 (fr) | 1966-04-21 | 1966-04-21 | Nouveau composé analgésique et anti-inflammatoire. |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES338641A1 true ES338641A1 (es) | 1968-04-01 |
Family
ID=19737675
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES338641A Expired ES338641A1 (es) | 1966-04-21 | 1967-03-29 | Procedimiento para la obtencion de un compuesto analgesico y antiinflamatorio. |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US3453366A (oth) |
| BE (1) | BE697096A (oth) |
| CH (1) | CH469724A (oth) |
| ES (1) | ES338641A1 (oth) |
| GB (1) | GB1116196A (oth) |
| MC (1) | MC614A1 (oth) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4302589A (en) * | 1980-05-08 | 1981-11-24 | American Cyanamid Company | Cis-mono and disubstituted-2-methyl-3-[(piperazinyl) and (piperidino)ethyl]indolines, intermediates for their preparation and methods of preparation |
| GB8830312D0 (en) * | 1988-12-28 | 1989-02-22 | Lundbeck & Co As H | Heterocyclic compounds |
| DE4101686A1 (de) * | 1991-01-22 | 1992-07-23 | Merck Patent Gmbh | Indolderivate |
| JPH10503501A (ja) * | 1994-08-03 | 1998-03-31 | アスタ メディカ アクチエンゲゼルシャフト | 抗喘息、抗アレルギー、抗炎症及び免疫修飾作用を有するインドール、インダゾール、ピリドピロール及びピリドピラゾール誘導体 |
| DE19934432A1 (de) * | 1999-07-22 | 2001-02-01 | Merck Patent Gmbh | Indolderivate |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3328407A (en) * | 1966-10-07 | 1967-06-27 | Sterling Drug Inc | 1-(indolyl lower-alkyl)-4-phenyl-piperazines |
-
1966
- 1966-04-21 MC MC617A patent/MC614A1/fr unknown
-
1967
- 1967-03-22 CH CH410667A patent/CH469724A/fr unknown
- 1967-03-29 ES ES338641A patent/ES338641A1/es not_active Expired
- 1967-03-31 GB GB14874/67A patent/GB1116196A/en not_active Expired
- 1967-04-10 US US629390A patent/US3453366A/en not_active Expired - Lifetime
- 1967-04-17 BE BE697096D patent/BE697096A/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CH469724A (fr) | 1969-03-15 |
| GB1116196A (en) | 1968-06-06 |
| US3453366A (en) | 1969-07-01 |
| BE697096A (oth) | 1967-10-02 |
| MC614A1 (fr) | 1967-05-31 |
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