ES338059A1 - Procedimiento para preparacion de nuevos derivados de mor- folina. - Google Patents
Procedimiento para preparacion de nuevos derivados de mor- folina.Info
- Publication number
- ES338059A1 ES338059A1 ES338059A ES338059A ES338059A1 ES 338059 A1 ES338059 A1 ES 338059A1 ES 338059 A ES338059 A ES 338059A ES 338059 A ES338059 A ES 338059A ES 338059 A1 ES338059 A1 ES 338059A1
- Authority
- ES
- Spain
- Prior art keywords
- benzyl
- morpholine
- cis
- diequat
- alpha
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 125000000325 methylidene group Chemical group [H]C([H])=* 0.000 title 1
- WVDDGKGOMKODPV-UHFFFAOYSA-N hydroxymethyl benzene Natural products OCC1=CC=CC=C1 WVDDGKGOMKODPV-UHFFFAOYSA-N 0.000 abstract 14
- -1 polymethyleneimino group Polymers 0.000 abstract 14
- YNAVUWVOSKDBBP-UHFFFAOYSA-N Morpholine Chemical group C1COCCN1 YNAVUWVOSKDBBP-UHFFFAOYSA-N 0.000 abstract 7
- 235000019445 benzyl alcohol Nutrition 0.000 abstract 7
- LZCLXQDLBQLTDK-UHFFFAOYSA-N ethyl 2-hydroxypropanoate Chemical compound CCOC(=O)C(C)O LZCLXQDLBQLTDK-UHFFFAOYSA-N 0.000 abstract 6
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 6
- 239000002253 acid Substances 0.000 abstract 4
- 150000001875 compounds Chemical class 0.000 abstract 4
- 150000002431 hydrogen Chemical group 0.000 abstract 4
- 229910052739 hydrogen Inorganic materials 0.000 abstract 4
- 239000001257 hydrogen Substances 0.000 abstract 4
- 150000003839 salts Chemical class 0.000 abstract 4
- WFDIJRYMOXRFFG-UHFFFAOYSA-N Acetic anhydride Chemical compound CC(=O)OC(C)=O WFDIJRYMOXRFFG-UHFFFAOYSA-N 0.000 abstract 3
- 125000005002 aryl methyl group Chemical group 0.000 abstract 3
- SXQFCVDSOLSHOQ-UHFFFAOYSA-N lactamide Chemical compound CC(O)C(N)=O SXQFCVDSOLSHOQ-UHFFFAOYSA-N 0.000 abstract 3
- 125000001570 methylene group Chemical group [H]C([H])([*:1])[*:2] 0.000 abstract 3
- LCTONWCANYUPML-UHFFFAOYSA-N Pyruvic acid Chemical compound CC(=O)C(O)=O LCTONWCANYUPML-UHFFFAOYSA-N 0.000 abstract 2
- 125000004423 acyloxy group Chemical group 0.000 abstract 2
- 150000001299 aldehydes Chemical class 0.000 abstract 2
- 125000005236 alkanoylamino group Chemical group 0.000 abstract 2
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 abstract 2
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 2
- DTYGMEIVDDVIAU-UHFFFAOYSA-N 2-[2,3-bis(phenylmethoxy)phenyl]-2-hydroxyacetonitrile Chemical compound C(C1=CC=CC=C1)OC1=C(C(C#N)O)C=CC=C1OCC1=CC=CC=C1 DTYGMEIVDDVIAU-UHFFFAOYSA-N 0.000 abstract 1
- YNJSNEKCXVFDKW-UHFFFAOYSA-N 3-(5-amino-1h-indol-3-yl)-2-azaniumylpropanoate Chemical compound C1=C(N)C=C2C(CC(N)C(O)=O)=CNC2=C1 YNJSNEKCXVFDKW-UHFFFAOYSA-N 0.000 abstract 1
- PTVSRINJXWDIKP-UHFFFAOYSA-N Ethyl 4-pentenoate Chemical compound CCOC(=O)CCC=C PTVSRINJXWDIKP-UHFFFAOYSA-N 0.000 abstract 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- HQMLIDZJXVVKCW-REOHCLBHSA-N L-alaninamide Chemical compound C[C@H](N)C(N)=O HQMLIDZJXVVKCW-REOHCLBHSA-N 0.000 abstract 1
- GOPYZMJAIPBUGX-UHFFFAOYSA-N [O-2].[O-2].[Mn+4] Chemical class [O-2].[O-2].[Mn+4] GOPYZMJAIPBUGX-UHFFFAOYSA-N 0.000 abstract 1
- 125000003282 alkyl amino group Chemical group 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 150000001412 amines Chemical class 0.000 abstract 1
- ROBXZHNBBCHEIQ-BYPYZUCNSA-N ethyl (2s)-2-aminopropanoate Chemical compound CCOC(=O)[C@H](C)N ROBXZHNBBCHEIQ-BYPYZUCNSA-N 0.000 abstract 1
- MFZSRRBSNGQXRR-UHFFFAOYSA-N ethyl 3-(oxiran-2-yl)propanoate Chemical compound CCOC(=O)CCC1CO1 MFZSRRBSNGQXRR-UHFFFAOYSA-N 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- WOFDVDFSGLBFAC-UHFFFAOYSA-N lactonitrile Chemical compound CC(O)C#N WOFDVDFSGLBFAC-UHFFFAOYSA-N 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 150000002780 morpholines Chemical class 0.000 abstract 1
- 230000001590 oxidative effect Effects 0.000 abstract 1
- 229940107700 pyruvic acid Drugs 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
- C07D265/28—1,4-Oxazines; Hydrogenated 1,4-oxazines
- C07D265/30—1,4-Oxazines; Hydrogenated 1,4-oxazines not condensed with other rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
- C07D303/02—Compounds containing oxirane rings
- C07D303/38—Compounds containing oxirane rings with hydrocarbon radicals, substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D303/40—Compounds containing oxirane rings with hydrocarbon radicals, substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals by ester radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/10—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
- C07D317/14—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D317/28—Radicals substituted by nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D317/46—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
- C07D317/48—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
- C07D317/50—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to atoms of the carbocyclic ring
- C07D317/58—Radicals substituted by nitrogen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Motorcycle And Bicycle Frame (AREA)
- Testing Of Balance (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH381666A CH471146A (de) | 1966-03-16 | 1966-03-16 | Verfahren zur Herstellung von neuen Morpholinderivaten |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES338059A1 true ES338059A1 (es) | 1968-06-16 |
Family
ID=4264074
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES338059A Expired ES338059A1 (es) | 1966-03-16 | 1967-03-15 | Procedimiento para preparacion de nuevos derivados de mor- folina. |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US3658806A (en:Method) |
| AT (1) | AT265300B (en:Method) |
| BE (1) | BE695539A (en:Method) |
| CH (1) | CH471146A (en:Method) |
| DE (1) | DE1695011A1 (en:Method) |
| DK (1) | DK115182B (en:Method) |
| ES (1) | ES338059A1 (en:Method) |
| FR (2) | FR1514737A (en:Method) |
| GB (1) | GB1185987A (en:Method) |
| GR (1) | GR36361B (en:Method) |
| IL (1) | IL27611A (en:Method) |
| NL (1) | NL6703912A (en:Method) |
| NO (1) | NO122924B (en:Method) |
| SE (1) | SE329849B (en:Method) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2325379A1 (fr) * | 1975-09-29 | 1977-04-22 | Cerm Cent Europ Rech Mauvernay | Nouveaux derives de 2-(2-hydroxyethyl)tetrahydro-1,4 oxazines substituees et leur application comme medicaments antispasmodique |
| US4252801A (en) * | 1980-01-04 | 1981-02-24 | E. R. Squibb & Sons, Inc. | Morpholinyl acetamide derivatives and use thereof |
| ES2684821T3 (es) | 2005-12-29 | 2018-10-04 | Lexicon Pharmaceuticals, Inc. | Derivados de aminoácidos multicíclicos y métodos de su uso |
-
1966
- 1966-03-16 CH CH381666A patent/CH471146A/de not_active IP Right Cessation
-
1967
- 1967-03-15 IL IL27611A patent/IL27611A/xx unknown
- 1967-03-15 SE SE03580/67A patent/SE329849B/xx unknown
- 1967-03-15 DK DK134567AA patent/DK115182B/da unknown
- 1967-03-15 ES ES338059A patent/ES338059A1/es not_active Expired
- 1967-03-15 NO NO167302A patent/NO122924B/no unknown
- 1967-03-15 AT AT249767A patent/AT265300B/de active
- 1967-03-15 BE BE695539D patent/BE695539A/xx unknown
- 1967-03-15 GR GR670136361A patent/GR36361B/el unknown
- 1967-03-15 GB GB02107/67A patent/GB1185987A/en not_active Expired
- 1967-03-15 DE DE19671695011 patent/DE1695011A1/de active Pending
- 1967-03-15 NL NL6703912A patent/NL6703912A/xx unknown
- 1967-03-16 FR FR99069A patent/FR1514737A/fr not_active Expired
- 1967-06-15 FR FR110528A patent/FR6511M/fr not_active Expired
-
1969
- 1969-01-30 US US795349*A patent/US3658806A/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| DE1695011A1 (de) | 1972-03-30 |
| US3658806A (en) | 1972-04-25 |
| SE329849B (en:Method) | 1970-10-26 |
| NL6703912A (en:Method) | 1967-09-18 |
| NO122924B (en:Method) | 1971-09-06 |
| GB1185987A (en) | 1970-04-02 |
| FR6511M (en:Method) | 1968-12-02 |
| CH471146A (de) | 1969-04-15 |
| GR36361B (el) | 1969-02-04 |
| DK115182B (da) | 1969-09-15 |
| BE695539A (en:Method) | 1967-09-15 |
| FR1514737A (fr) | 1968-02-23 |
| AT265300B (de) | 1968-10-10 |
| IL27611A (en) | 1970-12-24 |
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