ES332516A1 - Procedure for the preparation of imidazole derivatives. (Machine-translation by Google Translate, not legally binding) - Google Patents

Abstract

Process for the preparation of imidazole derivatives of the general formula I, ** (See formula) ** and its tautomeric forms, in which R1 means an alkyl group of lower molecular weight, a lower molecular weight alkenyl group, a cycloalkyl group, a lower molecular weight cycloalkyl-alkyl group, a lower molecular weight dialkylamino-alkyl group, an alkoxy-alkyl group of molecular weight lower, a monocarbocyclic aryl group, a monocarbocyclic aralkyl group of lower molecular weight, a pyridyl group, a monocarbocyclic aryl group, substituted one, two or three times, independently of each other, by lower molecular weight alkyl groups, by weight alkoxy groups lower molecular weight, by halogen atoms or by trifluoromethyl groups, and R2 means a hydrogen atom or an alkyl group of lower molecular weight, and R3 means a hydrogen atom, a monocarbocyclic aryl group, substituted one, two or three times, independently of each other, by lower molecular weight alkyl groups, by lower molecular weight alkoxy groups, by trifluoromethyl groups or by halogen atoms, or in case R1 means a peridylic group, it can also be a lower molecular weight alkyl group, characterized in that a compound of the general formula II, ** (See formula) ** and its tautomeric forms in which R1, R2 and R3 have the meanings indicated above and C = X means a carbonyl group or a functional group, which can be transformed by hydrolysis or by oxidation in a carbonyl group, heated in solution as such, or prepared in situ. (Machine-translation by Google Translate, not legally binding)