ES332322A1 - Procedure for preparing pteridine compounds. (Machine-translation by Google Translate, not legally binding) - Google Patents
Procedure for preparing pteridine compounds. (Machine-translation by Google Translate, not legally binding)Info
- Publication number
- ES332322A1 ES332322A1 ES0332322A ES332322A ES332322A1 ES 332322 A1 ES332322 A1 ES 332322A1 ES 0332322 A ES0332322 A ES 0332322A ES 332322 A ES332322 A ES 332322A ES 332322 A1 ES332322 A1 ES 332322A1
- Authority
- ES
- Spain
- Prior art keywords
- aryl
- mononuclear
- lower alkyl
- aliphatic
- translation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
- C07D241/10—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D241/14—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D241/24—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D241/26—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with nitrogen atoms directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D475/00—Heterocyclic compounds containing pteridine ring systems
- C07D475/06—Heterocyclic compounds containing pteridine ring systems with a nitrogen atom directly attached in position 4
- C07D475/08—Heterocyclic compounds containing pteridine ring systems with a nitrogen atom directly attached in position 4 with a nitrogen atom directly attached in position 2
Abstract
Process for preparing pteridine compounds, which consists of reacting 3-amino-5-X-6-halopyrazinonitrile and guanidine to form 2,4-diamino-6-halo-7-X-pteridine, according to which, in each case one of the foregoing products, halo is selected from chlorine, bromine and iodine, and X is selected from hydrogen, lower aliphatic oxide, lower aryl-aliphatic mononuclear oxime, lower aliphatic thio, aryl-aliphatic lower mononuclear thio, lower aliphatic, mononuclear aryl Y (see formula) in which R and R1 are chosen separately from hydrogen, alkoxy, lower alkyl, lower haloalkyl, lower hydroxyalkyl, lower cycloalkyl, lower alkyl, aryl-mononuclear lower alkyl, (lower alkyl substituted aryl) -lower alkyl, (halo) mononuclear aryl) -lower alkyl, lower aminoalkyl, furyl lower alkyl, pyrridylalkyl lower, mononuclear aryl and in that (see formula) where n is a number from 4 to 6. (Machine-translation by Google Translate, not legally binding)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US49289865A | 1965-10-04 | 1965-10-04 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES332322A1 true ES332322A1 (en) | 1967-07-16 |
Family
ID=23958060
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES0332322A Expired ES332322A1 (en) | 1965-10-04 | 1966-09-29 | Procedure for preparing pteridine compounds. (Machine-translation by Google Translate, not legally binding) |
Country Status (9)
| Country | Link |
|---|---|
| BE (1) | BE687730A (en) |
| BR (1) | BR6683209D0 (en) |
| CH (1) | CH479601A (en) |
| DE (1) | DE1620034A1 (en) |
| ES (1) | ES332322A1 (en) |
| FR (1) | FR6028M (en) |
| GB (1) | GB1149640A (en) |
| IL (1) | IL26578A (en) |
| NL (1) | NL6613936A (en) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2005231507B2 (en) | 2004-04-08 | 2012-03-01 | Targegen, Inc. | Benzotriazine inhibitors of kinases |
| JP5275628B2 (en) | 2004-08-25 | 2013-08-28 | ターゲジェン インコーポレーティッド | Heterocyclic compounds and methods of use |
| US7691858B2 (en) | 2006-04-25 | 2010-04-06 | Targegen, Inc. | Kinase inhibitors and methods of use thereof |
-
1966
- 1966-09-26 IL IL2657866A patent/IL26578A/en unknown
- 1966-09-27 BR BR18320966A patent/BR6683209D0/en unknown
- 1966-09-28 GB GB4340166A patent/GB1149640A/en not_active Expired
- 1966-09-28 CH CH1397766A patent/CH479601A/en not_active IP Right Cessation
- 1966-09-29 ES ES0332322A patent/ES332322A1/en not_active Expired
- 1966-10-03 NL NL6613936A patent/NL6613936A/xx unknown
- 1966-10-03 BE BE687730D patent/BE687730A/xx unknown
- 1966-10-03 DE DE19661620034 patent/DE1620034A1/en active Pending
- 1966-12-23 FR FR88769A patent/FR6028M/fr not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| BR6683209D0 (en) | 1973-12-26 |
| DE1620034A1 (en) | 1970-02-05 |
| NL6613936A (en) | 1967-04-05 |
| BE687730A (en) | 1967-04-03 |
| GB1149640A (en) | 1969-04-23 |
| CH479601A (en) | 1969-10-15 |
| IL26578A (en) | 1970-11-30 |
| FR6028M (en) | 1968-05-13 |
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