ES329462A1 - Un procedimiento para la preparacion de bencenosulfonilureas - Google Patents

Un procedimiento para la preparacion de bencenosulfonilureas

Info

Publication number
ES329462A1
ES329462A1 ES0329462A ES329462A ES329462A1 ES 329462 A1 ES329462 A1 ES 329462A1 ES 0329462 A ES0329462 A ES 0329462A ES 329462 A ES329462 A ES 329462A ES 329462 A1 ES329462 A1 ES 329462A1
Authority
ES
Spain
Prior art keywords
substituted
formula
salts
ethers
see formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES0329462A
Other languages
English (en)
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hoechst AG
Original Assignee
Farbwerke Hoechst AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=7101195&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES329462(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Farbwerke Hoechst AG filed Critical Farbwerke Hoechst AG
Publication of ES329462A1 publication Critical patent/ES329462A1/es
Expired legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/64Sulfonylureas, e.g. glibenclamide, tolbutamide, chlorpropamide
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C303/00Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides
    • C07C303/36Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides of amides of sulfonic acids
    • C07C303/40Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides of amides of sulfonic acids by reactions not involving the formation of sulfonamide groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C311/00Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/50Compounds containing any of the groups, X being a hetero atom, Y being any atom
    • C07C311/52Y being a hetero atom
    • C07C311/54Y being a hetero atom either X or Y, but not both, being nitrogen atoms, e.g. N-sulfonylurea
    • C07C311/57Y being a hetero atom either X or Y, but not both, being nitrogen atoms, e.g. N-sulfonylurea having sulfur atoms of the sulfonylurea groups bound to carbon atoms of six-membered aromatic rings
    • C07C311/58Y being a hetero atom either X or Y, but not both, being nitrogen atoms, e.g. N-sulfonylurea having sulfur atoms of the sulfonylurea groups bound to carbon atoms of six-membered aromatic rings having nitrogen atoms of the sulfonylurea groups bound to hydrogen atoms or to acyclic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D309/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/02Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D309/08Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D309/14Nitrogen atoms not forming part of a nitro radical
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00Systems containing only non-condensed rings
    • C07C2601/12Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14The ring being saturated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Macromonomer-Based Addition Polymer (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
ES0329462A 1965-07-27 1966-07-23 Un procedimiento para la preparacion de bencenosulfonilureas Expired ES329462A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DEF46721A DE1301812B (de) 1965-07-27 1965-07-27 Verfahren zur Herstellung von Benzolsulfonylharnstoffen

Publications (1)

Publication Number Publication Date
ES329462A1 true ES329462A1 (es) 1967-12-01

Family

ID=7101195

Family Applications (15)

Application Number Title Priority Date Filing Date
ES0329462A Expired ES329462A1 (es) 1965-07-27 1966-07-23 Un procedimiento para la preparacion de bencenosulfonilureas
ES344046A Expired ES344046A1 (es) 1965-07-27 1967-08-11 Procedimiento para la obtencion de n-(4- (beta-<2-metoxi-5-clorobenzamido>-etil) -bencenosulfonil)-n'- (4-metil-ciclo- hexil) -urea.
ES344049A Expired ES344049A1 (es) 1965-07-27 1967-08-11 Procedimiento para la obtencion de n-(4-(beta-2-metoxi-4- cloro-benzamido>-etil)-bencenosulfonil)-n'-(4-metil-ciclohe-xil)-urea.
ES344048A Expired ES344048A1 (es) 1965-07-27 1967-08-11 Procedimiento para la obtencion de n-(4-(beta-2-metoxi-5- metil-benzamido - etil)-benzolsulfonil) - n' - (4 metil-ci- clohexil)-urea.
ES344044A Expired ES344044A1 (es) 1965-07-27 1967-08-11 Procedimiento para la obtencion de bencenosulfonilureas.
ES344047A Expired ES344047A1 (es) 1965-07-27 1967-08-11 Procedimiento para la obtencion de n-(4-(beta- <2-metoxi- 5-bromobenzamido>-etil) - bencenosulfonil) -n'-(4-metilciclo-hexil)-urea.
ES344045A Expired ES344045A1 (es) 1965-07-27 1967-08-11 Procedimiento para la obtencion de n-(4 - (beta-<2-metoxi- 5 -cloro-benzamido>-etil)-bencenosulfonil)-n'-ciclohexil - urea.
ES355479A Expired ES355479A1 (es) 1965-07-27 1968-06-26 Procedimiento para la obtencion de n-(4-(beta-<2-metoxi-5- cloro-benzamido>-etil) -bencenosulfonil)-n'-ciclohexil-urea.
ES355480A Expired ES355480A1 (es) 1965-07-27 1968-06-26 Procedimiento para la obtencion de n-(4-(beta-<2-metoxi-5- clorobenzamido>-etil)-bencenosulfonil)-n'-ciclohexilurea.
ES355477A Expired ES355477A1 (es) 1965-07-27 1968-06-26 Procedimiento para la obtencion de n-(4-(beta-<2-metoxi-5- clorobenzamido>-etil)-bencenosulfonil)-n'-ciclohexilurea.
ES355474A Expired ES355474A1 (es) 1965-07-27 1968-06-26 Procedimiento para la obtencion de n-(4-(beta-<2-metoxi-5- clorobenzamido>-etil)-bencenosulfonil)-n'-ciclohexilurea.
ES355478A Expired ES355478A1 (es) 1965-07-27 1968-06-26 Procedimiento para la obtencion de n-(4-(beta-<2-metoxi-5- clorobenzamido>-etil)-bencenosulfonil)-n'-ciclohexilurea.
ES355481A Expired ES355481A1 (es) 1965-07-27 1968-06-26 Procedimiento para la obtencion de n-(4-(beta-<2-metoxi-5- cloro-benzamido>-etil)-bencenosulfonil)-n'-ciclohexil-urea.
ES355475A Expired ES355475A1 (es) 1965-07-27 1968-06-26 Procedimiento para la obtencion de n-(4-(beta-<2-metoxi-5- clorobenzamido>-etil)-bencenosulfonil)-n'-ciclohexilurea.
ES355476A Expired ES355476A1 (es) 1965-07-27 1968-06-26 Procedimiento para la obtencion de n-(4-(beta-<2-metoxi-5- clorobenzamido>-etil)-bencenosulfonil)-n'-ciclohexilurea.

Family Applications After (14)

Application Number Title Priority Date Filing Date
ES344046A Expired ES344046A1 (es) 1965-07-27 1967-08-11 Procedimiento para la obtencion de n-(4- (beta-<2-metoxi-5-clorobenzamido>-etil) -bencenosulfonil)-n'- (4-metil-ciclo- hexil) -urea.
ES344049A Expired ES344049A1 (es) 1965-07-27 1967-08-11 Procedimiento para la obtencion de n-(4-(beta-2-metoxi-4- cloro-benzamido>-etil)-bencenosulfonil)-n'-(4-metil-ciclohe-xil)-urea.
ES344048A Expired ES344048A1 (es) 1965-07-27 1967-08-11 Procedimiento para la obtencion de n-(4-(beta-2-metoxi-5- metil-benzamido - etil)-benzolsulfonil) - n' - (4 metil-ci- clohexil)-urea.
ES344044A Expired ES344044A1 (es) 1965-07-27 1967-08-11 Procedimiento para la obtencion de bencenosulfonilureas.
ES344047A Expired ES344047A1 (es) 1965-07-27 1967-08-11 Procedimiento para la obtencion de n-(4-(beta- <2-metoxi- 5-bromobenzamido>-etil) - bencenosulfonil) -n'-(4-metilciclo-hexil)-urea.
ES344045A Expired ES344045A1 (es) 1965-07-27 1967-08-11 Procedimiento para la obtencion de n-(4 - (beta-<2-metoxi- 5 -cloro-benzamido>-etil)-bencenosulfonil)-n'-ciclohexil - urea.
ES355479A Expired ES355479A1 (es) 1965-07-27 1968-06-26 Procedimiento para la obtencion de n-(4-(beta-<2-metoxi-5- cloro-benzamido>-etil) -bencenosulfonil)-n'-ciclohexil-urea.
ES355480A Expired ES355480A1 (es) 1965-07-27 1968-06-26 Procedimiento para la obtencion de n-(4-(beta-<2-metoxi-5- clorobenzamido>-etil)-bencenosulfonil)-n'-ciclohexilurea.
ES355477A Expired ES355477A1 (es) 1965-07-27 1968-06-26 Procedimiento para la obtencion de n-(4-(beta-<2-metoxi-5- clorobenzamido>-etil)-bencenosulfonil)-n'-ciclohexilurea.
ES355474A Expired ES355474A1 (es) 1965-07-27 1968-06-26 Procedimiento para la obtencion de n-(4-(beta-<2-metoxi-5- clorobenzamido>-etil)-bencenosulfonil)-n'-ciclohexilurea.
ES355478A Expired ES355478A1 (es) 1965-07-27 1968-06-26 Procedimiento para la obtencion de n-(4-(beta-<2-metoxi-5- clorobenzamido>-etil)-bencenosulfonil)-n'-ciclohexilurea.
ES355481A Expired ES355481A1 (es) 1965-07-27 1968-06-26 Procedimiento para la obtencion de n-(4-(beta-<2-metoxi-5- cloro-benzamido>-etil)-bencenosulfonil)-n'-ciclohexil-urea.
ES355475A Expired ES355475A1 (es) 1965-07-27 1968-06-26 Procedimiento para la obtencion de n-(4-(beta-<2-metoxi-5- clorobenzamido>-etil)-bencenosulfonil)-n'-ciclohexilurea.
ES355476A Expired ES355476A1 (es) 1965-07-27 1968-06-26 Procedimiento para la obtencion de n-(4-(beta-<2-metoxi-5- clorobenzamido>-etil)-bencenosulfonil)-n'-ciclohexilurea.

Country Status (22)

Country Link
JP (1) JPS526985B1 (pt)
AT (11) AT278032B (pt)
BE (2) BE684654A (pt)
BR (2) BR6681115D0 (pt)
CH (1) CH478103A (pt)
CY (2) CY534A (pt)
DE (1) DE1301812B (pt)
DK (2) DK117419B (pt)
ES (15) ES329462A1 (pt)
FI (1) FI45959C (pt)
FR (1) FR5943M (pt)
GB (2) GB1149391A (pt)
IL (2) IL26016A (pt)
IN (3) IN139506B (pt)
IS (2) IS756B6 (pt)
IT (2) IT1043760B (pt)
LU (2) LU51617A1 (pt)
MC (1) MC601A1 (pt)
MY (2) MY7000111A (pt)
NL (1) NL6610580A (pt)
NO (2) NO121834B (pt)
SE (1) SE328566B (pt)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1670901A1 (de) * 1967-08-09 1971-03-18 Hoechst Ag Verfahren zur Herstellung von Benzolsulfonylharnstoffen
DE3833439A1 (de) * 1988-10-01 1991-09-12 Hoechst Ag Verfahren zur mikronisierung von glibenclamid

Also Published As

Publication number Publication date
ES344044A1 (es) 1968-12-16
ES344049A1 (es) 1969-05-16
NO121834B (pt) 1971-04-19
AT274839B (de) 1969-10-10
AT278031B (de) 1970-01-26
BR6681115D0 (pt) 1973-12-26
ES355474A1 (es) 1969-12-01
CY540A (en) 1970-05-22
FI45959C (fi) 1972-11-10
GB1153272A (en) 1969-05-29
ES355476A1 (es) 1969-12-01
IS756B6 (is) 1970-11-23
ES355477A1 (es) 1969-12-01
IL26016A (en) 1970-08-19
GB1149391A (en) 1969-04-23
MC601A1 (fr) 1967-03-21
MY7000086A (en) 1970-12-31
MY7000111A (en) 1970-12-31
NO123569B (pt) 1971-12-13
DK117419B (da) 1970-04-27
IS822B6 (is) 1972-12-29
IN139506B (pt) 1976-06-26
JPS526985B1 (pt) 1977-02-26
NL6610580A (pt) 1967-01-30
LU51616A1 (pt) 1968-03-14
AT275541B (de) 1969-10-27
AT274842B (de) 1969-10-10
FR5943M (pt) 1968-04-08
BR6681609D0 (pt) 1973-12-27
AT278032B (de) 1970-01-26
ES355475A1 (es) 1969-12-01
FI45959B (pt) 1972-07-31
BE684654A (pt) 1967-01-27
IT1043760B (it) 1980-02-29
AT279638B (pt) 1970-03-10
AT274830B (de) 1969-10-10
AT279637B (de) 1970-03-10
ES344045A1 (es) 1968-11-16
ES355480A1 (es) 1969-12-01
IN139503B (pt) 1976-06-26
IS1582A7 (is) 1967-01-28
ES355479A1 (es) 1970-03-01
CH478103A (de) 1969-09-15
ES344048A1 (es) 1970-02-01
AT274841B (de) 1969-10-10
ES355481A1 (es) 1970-03-01
ES344047A1 (es) 1968-12-16
IS1581A7 (is) 1967-01-28
LU51617A1 (pt) 1968-03-14
IT1043761B (it) 1980-02-29
BE684652A (pt) 1967-01-27
DK123652B (da) 1972-07-17
IN139501B (pt) 1976-06-26
ES344046A1 (es) 1969-05-01
DE1301812B (de) 1969-08-28
CY534A (en) 1970-04-07
SE328566B (pt) 1970-09-21
ES355478A1 (es) 1969-12-01
IL26194A (en) 1970-05-21
AT274840B (de) 1969-10-10
AT274838B (de) 1969-10-10

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19870926