ES329130A1 - Procedimiento de preparacion de nuevos derivados de la isoindolino sulfonilurea. - Google Patents
Procedimiento de preparacion de nuevos derivados de la isoindolino sulfonilurea.Info
- Publication number
- ES329130A1 ES329130A1 ES0329130A ES329130A ES329130A1 ES 329130 A1 ES329130 A1 ES 329130A1 ES 0329130 A ES0329130 A ES 0329130A ES 329130 A ES329130 A ES 329130A ES 329130 A1 ES329130 A1 ES 329130A1
- Authority
- ES
- Spain
- Prior art keywords
- radical
- isoindoline
- translation
- aryl
- amino
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- GWVMLCQWXVFZCN-UHFFFAOYSA-N isoindoline Chemical compound C1=CC=C2CNCC2=C1 GWVMLCQWXVFZCN-UHFFFAOYSA-N 0.000 title abstract 2
- GQSFASWYVBMKSL-UHFFFAOYSA-N 1-methyl-3-methylsulfonylurea Chemical compound CNC(=O)NS(C)(=O)=O GQSFASWYVBMKSL-UHFFFAOYSA-N 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- -1 alkyl radical Chemical class 0.000 abstract 6
- 125000003118 aryl group Chemical group 0.000 abstract 2
- HGCIXCUEYOPUTN-UHFFFAOYSA-N cyclohexene Chemical compound C1CCC=CC1 HGCIXCUEYOPUTN-UHFFFAOYSA-N 0.000 abstract 2
- 125000005843 halogen group Chemical group 0.000 abstract 2
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 2
- NKWOXRUJRCMCBH-UHFFFAOYSA-N 1,3-dihydroisoindol-2-amine Chemical compound C1=CC=C2CN(N)CC2=C1 NKWOXRUJRCMCBH-UHFFFAOYSA-N 0.000 abstract 1
- 239000004215 Carbon black (E152) Substances 0.000 abstract 1
- XDTMQSROBMDMFD-UHFFFAOYSA-N Cyclohexane Chemical compound C1CCCCC1 XDTMQSROBMDMFD-UHFFFAOYSA-N 0.000 abstract 1
- 125000000738 acetamido group Chemical group [H]C([H])([H])C(=O)N([H])[*] 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 150000007513 acids Chemical class 0.000 abstract 1
- 125000004442 acylamino group Chemical group 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 1
- 229930195733 hydrocarbon Natural products 0.000 abstract 1
- 150000002430 hydrocarbons Chemical class 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 150000003254 radicals Chemical class 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 229920006395 saturated elastomer Polymers 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/56—Ring systems containing three or more rings
- C07D209/58—[b]- or [c]-condensed
- C07D209/72—4,7-Endo-alkylene-iso-indoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/44—Iso-indoles; Hydrogenated iso-indoles
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Indole Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB29841/65A GB1146979A (en) | 1965-07-14 | 1965-07-14 | New isoindolino-sulphonylurea derivatives and process for preparing them |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES329130A1 true ES329130A1 (es) | 1967-05-01 |
Family
ID=10298074
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES0329130A Expired ES329130A1 (es) | 1965-07-14 | 1966-07-14 | Procedimiento de preparacion de nuevos derivados de la isoindolino sulfonilurea. |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US3503962A (enEXAMPLES) |
| AT (1) | AT263800B (enEXAMPLES) |
| BE (1) | BE683614A (enEXAMPLES) |
| BR (1) | BR6681171D0 (enEXAMPLES) |
| CH (1) | CH461500A (enEXAMPLES) |
| DE (1) | DE1620393A1 (enEXAMPLES) |
| DK (1) | DK118505B (enEXAMPLES) |
| ES (1) | ES329130A1 (enEXAMPLES) |
| FR (1) | FR5836M (enEXAMPLES) |
| GB (1) | GB1146979A (enEXAMPLES) |
| NL (2) | NL6608786A (enEXAMPLES) |
| NO (1) | NO119800B (enEXAMPLES) |
| SE (1) | SE303294B (enEXAMPLES) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1113879B (it) * | 1979-03-15 | 1986-01-27 | Farmatis Spa | Derivato isoindolinico,processo per la sua preparazione e composizioni terapeutiche che lo comprendono come principio attivo |
| RU2006106920A (ru) | 2003-08-06 | 2007-09-20 | Синомикс Инк. (Us) | Гетеро-олигомерные вкусовые рецепторы t1r, клеточные линии, которые экспрессируют указанные рецепторы и вкусовые соединения |
| US20060045953A1 (en) * | 2004-08-06 | 2006-03-02 | Catherine Tachdjian | Aromatic amides and ureas and their uses as sweet and/or umami flavor modifiers, tastants and taste enhancers |
| JP2008530017A (ja) * | 2005-02-04 | 2008-08-07 | セノミックス インコーポレイテッド | 食料用組成物のための風味調整剤として連結された有機部分を含む分子 |
| JP4734346B2 (ja) | 2005-02-04 | 2011-07-27 | セノミックス インコーポレイテッド | 連結ヘテロアリール部分を含む化合物、ならびに食用組成物のための新規なうまみフレーバー改変剤、味物質および味覚増強剤としての使用 |
| AR055329A1 (es) * | 2005-06-15 | 2007-08-15 | Senomyx Inc | Amidas bis-aromaticas y sus usos como modificadores de sabor dulce, saborizantes, y realzadores de sabor |
| TWI674069B (zh) | 2006-04-21 | 2019-10-11 | 美商賽諾米克斯公司 | 包含高度鮮味風味劑之可食用組合物及其製造方法 |
| MX2017010528A (es) | 2015-02-16 | 2018-11-12 | Univ Queensland | Sulfonilureas y compuestos relacionados y uso de estos. |
| EP3978489A1 (en) | 2017-07-07 | 2022-04-06 | Inflazome Limited | Novel sulfonamide carboxamide compounds |
| WO2019008029A1 (en) | 2017-07-07 | 2019-01-10 | Inflazome Limited | SULFONYLURATES AND SULFONYLTHIOURES AS INHIBITORS OF NLRP3 |
| JP2020531453A (ja) | 2017-08-15 | 2020-11-05 | インフレイゾーム リミテッド | Ｎｌｒｐ３阻害剤としてのスルホニルウレアおよびスルホニルチオウレア |
| EP3668843A1 (en) | 2017-08-15 | 2020-06-24 | Inflazome Limited | Sulfonylureas and sulfonylthioureas as nlrp3 inhibitors |
| BR112020002948A2 (pt) * | 2017-08-15 | 2020-08-11 | Inflazome Limited | novos compostos de sulfonamida-carboxamida |
| WO2019034692A1 (en) | 2017-08-15 | 2019-02-21 | Inflazome Limited | SULFONYLURATES AND SULFONYLTHIOURES AS INHIBITORS OF NLRP3 |
| WO2019092171A1 (en) | 2017-11-09 | 2019-05-16 | Inflazome Limited | Novel sulfonamide carboxamide compounds |
| EP3707134A1 (en) | 2017-11-09 | 2020-09-16 | Inflazome Limited | Novel sulfonamide carboxamide compounds |
| WO2019166619A1 (en) | 2018-03-02 | 2019-09-06 | Inflazome Limited | Novel compounds |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2408066A (en) * | 1938-05-05 | 1946-09-24 | Hentrich Winfried | P-amino-benzene-sulphamide derivatives |
-
0
- NL NL129208D patent/NL129208C/xx active
-
1965
- 1965-07-14 GB GB29841/65A patent/GB1146979A/en not_active Expired
-
1966
- 1966-06-24 NL NL6608786A patent/NL6608786A/xx unknown
- 1966-06-27 US US560809A patent/US3503962A/en not_active Expired - Lifetime
- 1966-07-04 BE BE683614D patent/BE683614A/xx unknown
- 1966-07-11 BR BR181171/66A patent/BR6681171D0/pt unknown
- 1966-07-12 CH CH1008966A patent/CH461500A/fr unknown
- 1966-07-12 NO NO163890A patent/NO119800B/no unknown
- 1966-07-13 AT AT675266A patent/AT263800B/de active
- 1966-07-14 DK DK365766AA patent/DK118505B/da unknown
- 1966-07-14 DE DE19661620393 patent/DE1620393A1/de not_active Withdrawn
- 1966-07-14 SE SE9672/66A patent/SE303294B/xx unknown
- 1966-07-14 ES ES0329130A patent/ES329130A1/es not_active Expired
- 1966-10-10 FR FR79316A patent/FR5836M/fr not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| BR6681171D0 (pt) | 1973-12-26 |
| US3503962A (en) | 1970-03-31 |
| NO119800B (enEXAMPLES) | 1970-07-06 |
| DE1620393A1 (de) | 1970-04-02 |
| DK118505B (da) | 1970-08-31 |
| FR5836M (enEXAMPLES) | 1968-03-04 |
| AT263800B (de) | 1968-08-12 |
| CH461500A (fr) | 1968-08-31 |
| BE683614A (enEXAMPLES) | 1967-01-04 |
| NL129208C (enEXAMPLES) | |
| GB1146979A (en) | 1969-03-26 |
| NL6608786A (enEXAMPLES) | 1967-01-16 |
| SE303294B (enEXAMPLES) | 1968-08-26 |
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