Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
BASF Schweiz AG
Original Assignee
Ciba Geigy AG
Ciba AG
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Filing date
Publication date
Priority claimed from CH880565Aexternal-prioritypatent/CH484177A/en
Application filed by Ciba Geigy AG, Ciba AGfiledCriticalCiba Geigy AG
Publication of ES328271A1publicationCriticalpatent/ES328271A1/en
Pharmaceuticals Containing Other Organic And Inorganic Compounds
(AREA)
Abstract
"Procedure for obtaining oxacepin derivatives", which correspond to the general name 10-aminoalkyl-11-X-10,11-dihydro-dibenzo [b, f] [1,4] oxacepin, in which X means 2 hydrogen atoms or an oxo radical and the amino radical is separated from the ring nitrogen atom by at least 2 carbon atoms, and in which at least one of the benzene rings contains a nitro radical, or the salts of the same, characterized in that in the 10-Ro-11-X-10, 11-dihydro-dibenzo [b, f] [1,4] oxacepin, which in at least one of the benzene rings contain a radical nitro and in which Ro means a transformable moiety in an aminoalkyl radical, or salts thereof, the radical Ro is converted to an aminoalkyl residue in which the amino radical is separated from the ring nitrogen atom by at least 2 atoms carbon, or b) in an ether N- (aminoalkyl) -N-Xo-amino-o'-Xoa-diphenyl, in which the two amino radicals are separated at least at 2 carbon atoms and at least one of the phenyl residues contains a nitro radical, and in which Xo means a hydrogen atom or an acyl radical and Xoa a substituent which under the conditions of the ring closure forms the radical of formula -C (= X) -, the ring is closed and, if desired, in an obtained compound an aminoalkyl radical is transformed into another amino alkyl moiety, and/or, if desired, a compound obtained is transformed in a salt or a salt obtained in the free compound or in another salt, and/or, if desired, a mixture of isomers obtained is transformed into the different isomers. (Machine-translation by Google Translate, not legally binding)
ES0328271A1965-06-231966-06-22Procedure for obtaining oxacepine derivatives (Machine-translation by Google Translate, not legally binding)
ExpiredES328271A1
(en)
Procedure for the preparation of compounds of 2- (2º-hydroxy-3º-propenyl-phenyl) -benzotriazol (Machine-translation by Google Translate, not legally binding)
Procedure for the obtaining of derivatives of 5,6,7,9, 10,14b-hexahidro-isoquinolo- (2,1-d) benzo (1,4) -diacepin-6ona. (Machine-translation by Google Translate, not legally binding)