|
US4806529A
(en)
*
|
1982-11-18 |
1989-02-21 |
Trustees Of Tufts College, Tufts University |
Tetracycline activity enhancement
|
|
US5589470A
(en)
*
|
1990-02-26 |
1996-12-31 |
Trustees Of Tufts College |
Reducing tetracycline resistance in living cells
|
|
US5064821A
(en)
*
|
1982-11-18 |
1991-11-12 |
Trustees Of Tufts College |
Method and compositions for overcoming tetracycline resistance within living cells
|
|
WO1993008806A1
(en)
*
|
1991-11-06 |
1993-05-13 |
Trustees Of Tufts College |
Reducing tetracycline resistance in living cells
|
|
US6756365B2
(en)
|
1991-11-06 |
2004-06-29 |
Trustees Of Tufts College |
Reducing tetracycline resistance in living cells
|
|
US6849615B2
(en)
|
1999-09-14 |
2005-02-01 |
Paratek Pharmaceuticals, Inc. |
13-substituted methacycline compounds
|
|
US8106225B2
(en)
*
|
1999-09-14 |
2012-01-31 |
Trustees Of Tufts College |
Methods of preparing substituted tetracyclines with transition metal-based chemistries
|
|
CN1399627A
(zh)
|
1999-09-14 |
2003-02-26 |
塔夫茨大学信托人 |
用基于过渡金属的化学制备取代四环素的方法
|
|
US6500812B2
(en)
|
1999-09-14 |
2002-12-31 |
Paratek Pharmaceuticals, Inc. |
13-substituted methacycline compounds
|
|
WO2001052858A1
(en)
*
|
2000-01-24 |
2001-07-26 |
Trustees Of Tufts College |
Tetracycline compounds for treatment of cryptosporidium parvum related disorders
|
|
HUP0300082A2
(en)
|
2000-03-31 |
2003-05-28 |
Paratek Pharmaceuticals |
7- and 9-carbamate, urea, thiourea, thiocarbamate, and heteroaryl-amino substituted tetracycline derivatives, process for their preparation and use and pharmaceutical compositions containing them
|
|
US6642270B2
(en)
*
|
2000-05-15 |
2003-11-04 |
Paratek Pharmaceuticals, Inc. |
7-substituted fused ring tetracycline compounds
|
|
US20020132798A1
(en)
*
|
2000-06-16 |
2002-09-19 |
Nelson Mark L. |
7-phenyl-substituted tetracycline compounds
|
|
US20040224927A1
(en)
*
|
2000-06-16 |
2004-11-11 |
Trustees Of Tufts College |
7-N-substituted phenyl tetracycline compounds
|
|
WO2001098236A2
(en)
*
|
2000-06-16 |
2001-12-27 |
Trustees Of Tufts College |
7-phenyl-substituted tetracycline compounds
|
|
BR0112265A
(pt)
*
|
2000-07-07 |
2003-06-24 |
Tufts College |
Compostos de tetraciclina substituìda, e de sanciclina 7-substituìda, método para tratar um estado responsivo à tetraciclina em um indivìduo, e, composição farmacêutica
|
|
BRPI0112269B8
(pt)
|
2000-07-07 |
2021-05-25 |
Paratek Pharm Innc |
composto de minociclina 9-aminometila substituída, e, composição farmacêutica
|
|
WO2002004404A2
(en)
|
2000-07-07 |
2002-01-17 |
Trustees Of Tufts College |
7,8 and 9-substituted tetracycline compounds
|
|
US20050143353A1
(en)
*
|
2000-07-07 |
2005-06-30 |
Paratek Pharmaceuticals, Inc. |
13-Substituted methacycline compounds
|
|
JP2004502751A
(ja)
|
2000-07-07 |
2004-01-29 |
トラスティーズ・オブ・タフツ・カレッジ |
13−置換されたメタサイクリン化合物
|
|
US7094806B2
(en)
*
|
2000-07-07 |
2006-08-22 |
Trustees Of Tufts College |
7, 8 and 9-substituted tetracycline compounds
|
|
HRP20030743A2
(en)
*
|
2001-03-13 |
2005-06-30 |
Paratek Pharmaceuticals |
7,9-substituted tetracycline compounds
|
|
EP1241160A1
(en)
*
|
2001-03-13 |
2002-09-18 |
Glaxo Group Limited |
Tetracycline derivatives and their use as antibiotic agents
|
|
US7553828B2
(en)
*
|
2001-03-13 |
2009-06-30 |
Paratek Pharmaceuticals, Inc. |
9-aminomethyl substituted minocycline compounds
|
|
AU2002250331A1
(en)
*
|
2001-03-13 |
2002-09-24 |
Paratek Pharmaceuticals, Inc. |
7-pyrollyl tetracycline compounds and methods of use thereof
|
|
EP1381372A2
(en)
|
2001-03-14 |
2004-01-21 |
Paratek Pharmaceuticals, Inc. |
Substituted tetracycline compounds as synergistic antifungal agents
|
|
JP2004530661A
(ja)
|
2001-03-14 |
2004-10-07 |
パラテック ファーマシューティカルズ インコーポレイテッド |
抗真菌剤としての置換テトラサイクリン化合物
|
|
US8088820B2
(en)
*
|
2001-04-24 |
2012-01-03 |
Paratek Pharmaceuticals, Inc. |
Substituted tetracycline compounds for the treatment of malaria
|
|
CA2444899C
(en)
|
2001-04-24 |
2011-06-21 |
Paratek Pharmaceuticals, Inc. |
Substituted tetracycline compounds for the treatment of malaria
|
|
EP2311798A1
(en)
|
2002-01-08 |
2011-04-20 |
Paratek Pharmaceuticals, Inc. |
4-dedimethylamino tetracycline compounds
|
|
AU2003214876B2
(en)
|
2002-01-23 |
2008-06-12 |
Dentsply International Inc. |
Irrigation solution and methods for use
|
|
EP1482926A4
(en)
|
2002-03-08 |
2006-04-12 |
Paratek Pharm Innc |
AMINO METHYL SUBSTITUTED TETRACYCLINE COMPOUNDS
|
|
WO2003079984A2
(en)
|
2002-03-21 |
2003-10-02 |
Paratek Pharmaceuticals, Inc. |
Substituted tetracycline compounds
|
|
WO2004006850A2
(en)
|
2002-07-12 |
2004-01-22 |
Paratek Pharmaceuticals, Inc |
3, 10, AND 12a SUBSTITUTED TETRACYCLINE COMPOUNDS
|
|
JP2006503898A
(ja)
|
2002-10-24 |
2006-02-02 |
パラテック ファーマシューティカルズ, インク. |
マラリア治療のための置換テトラサイクリン化合物
|
|
US20060287283A1
(en)
*
|
2003-07-09 |
2006-12-21 |
Paratek Pharmaceuticals, Inc. |
Prodrugs of 9-aminomethyl tetracycline compounds
|
|
CN1845897A
(zh)
|
2003-07-09 |
2006-10-11 |
帕拉特克药品公司 |
取代的四环素化合物
|
|
AU2004259661B2
(en)
|
2003-07-09 |
2011-11-10 |
Paratek Pharmaceuticals, Inc. |
Prodrugs of 9-aminomethyl tetracycline compounds
|
|
EP1716101A1
(en)
*
|
2004-01-15 |
2006-11-02 |
Paratek Pharmaceuticals, Inc. |
Aromatic a-ring derivatives of tetracycline compounds
|
|
TWI261038B
(en)
*
|
2004-08-11 |
2006-09-01 |
Bo-Cheng Chen |
Bicycle gear-shifting handgrip
|
|
US9993558B2
(en)
*
|
2004-10-01 |
2018-06-12 |
Ramscor, Inc. |
Sustained release eye drop formulations
|
|
WO2006047671A2
(en)
|
2004-10-25 |
2006-05-04 |
Paratek Pharmaceuticals, Inc. |
4-aminotetracyclines and methods of use thereof
|
|
US8466132B2
(en)
|
2004-10-25 |
2013-06-18 |
Paratek Pharmaceuticals, Inc. |
Substituted tetracycline compounds
|
|
AU2006210406C1
(en)
*
|
2005-02-04 |
2013-03-07 |
Paratek Pharmaceuticals, Inc. |
11a, 12-derivatives of tetracycline compounds
|
|
EP1910273A2
(en)
*
|
2005-07-21 |
2008-04-16 |
Paratek Pharmaceuticals, Inc. |
10-substituted tetracyclines and methods of use thereof
|
|
WO2007087416A2
(en)
|
2006-01-24 |
2007-08-02 |
Paratek Pharaceuticals, Inc. |
Methods of increasing oral bioavailability of tetracyclines
|
|
WO2007120913A2
(en)
*
|
2006-04-17 |
2007-10-25 |
Teva Pharmaceutical Industries Ltd. |
Isolation of tetracycline derivatives
|
|
US8198470B2
(en)
*
|
2006-04-24 |
2012-06-12 |
Teva Pharmaceutical Industries Ltd. |
Crystalline form II of tigecycline and processes for preparation thereof
|
|
SI2016045T1
(sl)
*
|
2006-04-24 |
2015-03-31 |
Teva Pharmaceutical Industries, Ltd. 5 Basel Street |
Kristalinična oblika tigeciklina in postopek za njegovo pripravo
|
|
EP2431469A3
(en)
*
|
2006-05-15 |
2012-05-30 |
Paratek Pharmaceuticals, Inc. |
Methods of regulating expression of genes or of gene products using substituted tetracycline compounds
|
|
US8440646B1
(en)
|
2006-10-11 |
2013-05-14 |
Paratek Pharmaceuticals, Inc. |
Substituted tetracycline compounds for treatment of Bacillus anthracis infections
|
|
PL2109602T3
(pl)
|
2006-12-21 |
2014-09-30 |
Paratek Pharm Innc |
Pochodne tetracyliny do leczenia zakażeń bakteryjnych, wirusowych i pasożytniczych
|
|
SI2120963T1
(sl)
|
2006-12-21 |
2019-02-28 |
Paratek Pharmaceuticals, Inc. |
Substituirane spojine tetraciklina za zdravljenje vnetnih kožnih motenj
|
|
EP2144614A1
(en)
|
2007-04-12 |
2010-01-20 |
Paratek Pharmaceuticals, Inc. |
Methods for treating spinal muscular atrophy using tetracycline compounds
|
|
EP2144870A2
(en)
|
2007-04-27 |
2010-01-20 |
Paratek Pharmaceuticals, Inc. |
Methods for synthesizing and purifying aminoalkyl tetracycline compounds
|
|
KR20100042276A
(ko)
|
2007-07-06 |
2010-04-23 |
파라테크 파마슈티컬스, 인크. |
치환 테트라사이클린 화합물의 합성방법
|
|
WO2009111064A2
(en)
|
2008-03-05 |
2009-09-11 |
Paratek Pharmaceuticals, Inc. |
Minocycline compounds and methods of use thereof
|
|
PT2271348T
(pt)
|
2008-03-28 |
2018-04-16 |
Paratek Pharm Innc |
Formulação de comprimido oral de composto de tetraciclina
|
|
EP2276342A4
(en)
*
|
2008-04-14 |
2012-02-22 |
Paratek Pharm Innc |
SUBSTITUTED TETRACYCLIN COMPOUNDS
|
|
TWI680117B
(zh)
|
2008-05-19 |
2019-12-21 |
派洛泰克藥物股份有限公司 |
四環素化合物之甲苯磺酸鹽及同素異形體
|
|
CN102215681A
(zh)
*
|
2008-09-19 |
2011-10-12 |
帕拉特克药品公司 |
用于治疗类风湿性关节炎的四环素化合物和相关的治疗方法
|
|
EP2990051B1
(en)
|
2009-04-10 |
2016-10-26 |
Tufts Medical Center, Inc. |
Par-1 activation by metalloproteinase-1 (mmp-1)
|
|
ES2985493T3
(es)
|
2011-05-12 |
2024-11-06 |
Almirall Llc |
Composición farmacéutica para administración oral que comprende sales cristalinas de amida del ácido (4S,4aS,5aR,12aS)-4-dimetilamino-3,10,12,12a-tetrahidroxi-7-[(metoxi(metil)amino)-metil]-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahidro-naftacen-2-carboxílico
|
|
US20210220238A1
(en)
*
|
2015-09-15 |
2021-07-22 |
Brian Morrow |
Single-serve oral rinse systems
|
|
AU2017353588B2
(en)
|
2016-11-01 |
2022-07-14 |
Paratek Pharmaceuticals, Inc. |
9-aminomethyl minocycline compounds and use thereof in treating Community-Acquired Bacterial Pneumonia (CABP)
|
|
CA3070663A1
(en)
|
2017-07-21 |
2019-01-24 |
Almirall, Llc |
Treatment of non-inflammatory lesions
|