ES320424A1 - Procedure for the obtaining of bencimidazoles. (Machine-translation by Google Translate, not legally binding) - Google Patents
Procedure for the obtaining of bencimidazoles. (Machine-translation by Google Translate, not legally binding)Info
- Publication number
- ES320424A1 ES320424A1 ES0320424A ES320424A ES320424A1 ES 320424 A1 ES320424 A1 ES 320424A1 ES 0320424 A ES0320424 A ES 0320424A ES 320424 A ES320424 A ES 320424A ES 320424 A1 ES320424 A1 ES 320424A1
- Authority
- ES
- Spain
- Prior art keywords
- formula
- moiety
- compound
- translation
- obtaining
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/22—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms directly attached to ring nitrogen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
Process for obtaining benzimidazoles of general formula I ** (See formula) ** wherein Ph means a 1,2-phenylene radical, R an aliphatic moiety, an araliphatic moiety, an aryl moiety or a heterocyclic moiety of an aromatic nature, A means a moiety, and an amino radical, its N-oxides and the salts of these compounds, or the quaternary derivatives thereof, characterized in that a compound of formula IV ** (See formula) ** or an N-oxide thereof, or a salt of these compounds, is reacted with an ester capable of reacting a compound of formula HO-A-Am, or a compound of formula V ** (See formula) ** wherein X means an esterified hydroxy radical, capable of reaction, or an N-oxide thereof, is reacted with a compound of formula H-Am, or in a compound of formula VI ** (See formula) ** wherein Ac represents an alkanoyl moiety, or an N-oxide thereof, the alkanoylene moiety is transformed to the alkylene moiety A by treatment with a light metal complex hydride. (Machine-translation by Google Translate, not legally binding)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US41664764A | 1964-12-07 | 1964-12-07 | |
| US484433A US3300505A (en) | 1964-12-07 | 1965-09-01 | Ether-2-r-substituted benzimidazoles and derivatives and acid addition salts thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES320424A1 true ES320424A1 (en) | 1966-10-16 |
Family
ID=27023435
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES0320424A Expired ES320424A1 (en) | 1964-12-07 | 1965-12-06 | Procedure for the obtaining of bencimidazoles. (Machine-translation by Google Translate, not legally binding) |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US3300505A (en) |
| AT (3) | AT257592B (en) |
| BE (1) | BE673339A (en) |
| CH (1) | CH480346A (en) |
| DE (1) | DE1545718A1 (en) |
| ES (1) | ES320424A1 (en) |
| FR (1) | FR1481945A (en) |
| GB (1) | GB1101149A (en) |
| NL (1) | NL6515833A (en) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3449498A (en) * | 1965-11-18 | 1969-06-10 | Ciba Geigy Corp | Analgesic compositions of a 4-aminoal-kylamino-quinazoline and 1-amino-alkoxybenzimidazole |
| GB1141936A (en) * | 1966-03-26 | 1969-02-05 | Shionogi & Co | Improvements in or relating to benzimidazole derivatives |
| US7405235B2 (en) * | 2001-05-04 | 2008-07-29 | Paratek Pharmaceuticals, Inc. | Transcription factor modulating compounds and methods of use thereof |
| CA2504448C (en) * | 2002-11-01 | 2012-06-19 | Paratek Pharmaceuticals, Inc. | Transcription factor modulating compounds and methods of use thereof |
| CA2562763A1 (en) | 2004-04-23 | 2006-07-20 | Paratek Pharmaceuticals, Inc. | Transcription factor modulating compounds and methods of use thereof |
| WO2008130368A2 (en) * | 2006-06-23 | 2008-10-30 | Paratek Pharmaceuticals, Inc. | Transcription factor modulating compounds and methods of use thereof |
| WO2009005551A2 (en) * | 2007-03-27 | 2009-01-08 | Paratek Pharmaceuticals, Inc. | Transcription factor modulating compounds and methods of use thereof |
| US20110059962A1 (en) * | 2009-04-22 | 2011-03-10 | Alekshun Michael N | Transcription factor modulating compounds and methods of use thereof |
| CN102414195B (en) * | 2009-04-28 | 2014-11-12 | 住友化学株式会社 | Fused heterocyclic compound and use thereof |
-
1965
- 1965-09-01 US US484433A patent/US3300505A/en not_active Expired - Lifetime
- 1965-12-02 CH CH1661965A patent/CH480346A/en not_active IP Right Cessation
- 1965-12-03 FR FR40811A patent/FR1481945A/en not_active Expired
- 1965-12-06 AT AT363666A patent/AT257592B/en active
- 1965-12-06 AT AT363566A patent/AT257591B/en active
- 1965-12-06 GB GB51657/65A patent/GB1101149A/en not_active Expired
- 1965-12-06 NL NL6515833A patent/NL6515833A/xx unknown
- 1965-12-06 BE BE673339A patent/BE673339A/xx unknown
- 1965-12-06 AT AT1094165A patent/AT256100B/en active
- 1965-12-06 ES ES0320424A patent/ES320424A1/en not_active Expired
- 1965-12-07 DE DE19651545718 patent/DE1545718A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| AT256100B (en) | 1967-08-10 |
| NL6515833A (en) | 1966-06-08 |
| DE1545718A1 (en) | 1969-07-10 |
| AT257591B (en) | 1967-10-10 |
| BE673339A (en) | 1966-06-06 |
| FR1481945A (en) | 1967-05-26 |
| CH480346A (en) | 1969-10-31 |
| GB1101149A (en) | 1968-01-31 |
| AT257592B (en) | 1967-10-10 |
| US3300505A (en) | 1967-01-24 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ES413188A1 (en) | 2-alkyl-3-acylpyrazolo(1,5-a)pyridines | |
| ES320424A1 (en) | Procedure for the obtaining of bencimidazoles. (Machine-translation by Google Translate, not legally binding) | |
| ES401623A1 (en) | Adenosine derivatives | |
| ES414956A1 (en) | Halogenated 4-(4'-bisphenylyl)-butanols | |
| ES381580A1 (en) | Hexahydro-fluoren-2-yloxy alkanoic acids and esters thereof | |
| ES317454A1 (en) | Procedure for the preparation of amidas of derivatives of lysergic acid. (Machine-translation by Google Translate, not legally binding) | |
| ES327297A1 (en) | Procedure for the obtaining of compounds derived from quinazoline. (Machine-translation by Google Translate, not legally binding) | |
| ES296634A1 (en) | Procedure for the production of new heterocyclic compounds (Machine-translation by Google Translate, not legally binding) | |
| ES360860A1 (en) | Procedure for the preparation of new derivatives of tiazepine. (Machine-translation by Google Translate, not legally binding) | |
| ES332163A1 (en) | Procedure for preparing a 1H-2,3-benzoxyacin - 4 (3h) ona. (Machine-translation by Google Translate, not legally binding) | |
| ES332381A1 (en) | Procedure for the preparation of steroids. (Machine-translation by Google Translate, not legally binding) | |
| ES461157A1 (en) | Bicyclomycin derivatives | |
| ES300057A1 (en) | Procedure for the production of compounds of the lignan series (Machine-translation by Google Translate, not legally binding) | |
| ES382147A1 (en) | A procedure for preparing N-substituted morpholine compounds. (Machine-translation by Google Translate, not legally binding) | |
| ES311820A1 (en) | Procedure for the production of indollic derivatives. (Machine-translation by Google Translate, not legally binding) | |
| ES384602A1 (en) | Procedure for the preparation of new basic pirrol derivatives. (Machine-translation by Google Translate, not legally binding) | |
| ES323792A1 (en) | Procedure for the synthesis of replaced hydrainic derivatives. (Machine-translation by Google Translate, not legally binding) | |
| ES328955A2 (en) | Procedure for the production of phenotyacin derivatives (Machine-translation by Google Translate, not legally binding) | |
| ES314065A2 (en) | Procedure for the preparation of new derivatives of imidazol. (Machine-translation by Google Translate, not legally binding) | |
| GB1056475A (en) | Process for preparing 4-amino-pyrazolone derivatives | |
| ES315038A1 (en) | Procedure for the preparation of 3-fenilpirrol derivatives. (Machine-translation by Google Translate, not legally binding) | |
| ES363845A1 (en) | Procedure for the preparation of new derivatives of imidazolidinone. (Machine-translation by Google Translate, not legally binding) | |
| ES313971A1 (en) | Procedure for the preparation of new derivatives of imidazol. (Machine-translation by Google Translate, not legally binding) | |
| ES267802A1 (en) | Procedure for obtaining derivatives of dihydrolyseric acid and its acidal salts of addition (Machine-translation by Google Translate, not legally binding) | |
| ES417353A1 (en) | Procedure for preparing quinoleine derivatives. (Machine-translation by Google Translate, not legally binding) |