ES307769A2 - A method for the preparation of a benzylguanidine. (Machine-translation by Google Translate, not legally binding) - Google Patents
A method for the preparation of a benzylguanidine. (Machine-translation by Google Translate, not legally binding)Info
- Publication number
- ES307769A2 ES307769A2 ES0307769A ES307769A ES307769A2 ES 307769 A2 ES307769 A2 ES 307769A2 ES 0307769 A ES0307769 A ES 0307769A ES 307769 A ES307769 A ES 307769A ES 307769 A2 ES307769 A2 ES 307769A2
- Authority
- ES
- Spain
- Prior art keywords
- formula
- benzylguanidine
- translation
- preparation
- machine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
- C07C275/70—Compounds containing any of the groups, e.g. isoureas
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Cardiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Heart & Thoracic Surgery (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
Improvements introduced in the object of the main patent no. 263,336, ie in a method for the preparation of a benzylguanidine, according to which a guanidine of formula (I) is prepared ** (See formula) ** wherein L is a phenyl group substituted at will in position 2 or 3 with a chlorine or bromine atom or a methyl group or L is a 2-thienyl group substituted at will in position 3 with a methyl group , and R1 and R2 are the same or different and each of them is a hydrogen atom or a methyl or ethyl group, characterized in that they comprise the reaction of a 0-alkylisourea of formula AOC (: NQ2) NHQ3 or a salt thereof with ammonia or a primary amine of formula Q1NH2 or a salt thereof, where Q1, Q2 and Q3 taken in any order represent LCH2-, R1, and R2 and A is a lower alkyl group of 1-6 carbon atoms. (Machine-translation by Google Translate, not legally binding)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB469/64A GB1084461A (en) | 1964-01-04 | 1964-01-04 | Preparation of guanidines |
| GB3191764 | 1964-08-05 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES307769A2 true ES307769A2 (en) | 1965-05-16 |
Family
ID=26235944
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES0307769A Expired ES307769A2 (en) | 1964-01-04 | 1965-01-02 | A method for the preparation of a benzylguanidine. (Machine-translation by Google Translate, not legally binding) |
Country Status (10)
| Country | Link |
|---|---|
| JP (2) | JPS4825174B1 (en) |
| AT (1) | AT264539B (en) |
| BR (1) | BR6466022D0 (en) |
| CH (1) | CH451113A (en) |
| DE (1) | DE1518215A1 (en) |
| DK (1) | DK115468B (en) |
| ES (1) | ES307769A2 (en) |
| FR (2) | FR1302943A (en) |
| GB (1) | GB1084461A (en) |
| NL (1) | NL6500013A (en) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1354513A (en) * | 1970-06-05 | 1974-06-05 | Wellcome Found | Substituted guanidine compounds |
| JPS57169809U (en) * | 1981-04-20 | 1982-10-26 |
-
1960
- 1960-12-21 FR FR847609A patent/FR1302943A/en not_active Expired
-
1964
- 1964-01-04 GB GB469/64A patent/GB1084461A/en not_active Expired
- 1964-12-31 DE DE19641518215 patent/DE1518215A1/en not_active Ceased
- 1964-12-31 BR BR166022/64A patent/BR6466022D0/en unknown
- 1964-12-31 CH CH1689564A patent/CH451113A/en unknown
-
1965
- 1965-01-02 ES ES0307769A patent/ES307769A2/en not_active Expired
- 1965-01-02 DK DK565AA patent/DK115468B/en unknown
- 1965-01-04 FR FR758A patent/FR87378E/en not_active Expired
- 1965-01-04 JP JP40000302A patent/JPS4825174B1/ja active Pending
- 1965-01-04 NL NL6500013A patent/NL6500013A/xx unknown
- 1965-01-04 AT AT2165A patent/AT264539B/en active
-
1970
- 1970-04-23 JP JP45034342A patent/JPS5138702B1/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| DE1518215A1 (en) | 1969-08-14 |
| FR87378E (en) | 1966-07-29 |
| BR6466022D0 (en) | 1973-08-02 |
| CH451113A (en) | 1968-05-15 |
| AT264539B (en) | 1968-09-10 |
| NL6500013A (en) | 1965-07-05 |
| JPS5138702B1 (en) | 1976-10-23 |
| GB1084461A (en) | 1967-09-20 |
| FR1302943A (en) | 1962-09-07 |
| JPS4825174B1 (en) | 1973-07-26 |
| DK115468B (en) | 1969-10-13 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD2A | Announcement of lapse in spain |
Effective date: 20170628 |