ES3024357T3 - Targeted ligand-payload based drug delivery for cell therapy - Google Patents

Targeted ligand-payload based drug delivery for cell therapy Download PDF

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Publication number
ES3024357T3
ES3024357T3 ES18754879T ES18754879T ES3024357T3 ES 3024357 T3 ES3024357 T3 ES 3024357T3 ES 18754879 T ES18754879 T ES 18754879T ES 18754879 T ES18754879 T ES 18754879T ES 3024357 T3 ES3024357 T3 ES 3024357T3
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cell
cells
drug delivery
delivery platform
drug
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ES18754879T
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Spanish (es)
Inventor
Philip S Low
Madduri Srinivasarao
Boning Zhang
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Purdue Research Foundation
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Purdue Research Foundation
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    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7088—Compounds having three or more nucleosides or nucleotides
    • A61K31/713—Double-stranded nucleic acids or oligonucleotides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14—Blood; Artificial blood
    • A61K35/17—Lymphocytes; B-cells; T-cells; Natural killer cells; Interferon-activated or cytokine-activated lymphocytes
    • A—HUMAN NECESSITIES
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    • A61K40/00—Cellular immunotherapy
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    • A61K40/11—T-cells, e.g. tumour infiltrating lymphocytes [TIL] or regulatory T [Treg] cells; Lymphokine-activated killer [LAK] cells
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    • A61K47/6901—Conjugates being cells, cell fragments, viruses, ghosts, red blood cells or viral vectors
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  • Proteomics, Peptides & Aminoacids (AREA)
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  • Biomedical Technology (AREA)
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  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
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  • Gastroenterology & Hepatology (AREA)
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  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
ES18754879T 2017-02-17 2018-02-17 Targeted ligand-payload based drug delivery for cell therapy Active ES3024357T3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201762460118P 2017-02-17 2017-02-17
PCT/US2018/018557 WO2018152451A1 (en) 2017-02-17 2018-02-17 Targeted ligand-payload based drug delivery for cell therapy

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ES3024357T3 true ES3024357T3 (en) 2025-06-04

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US (2) US12343403B2 (https=)
EP (2) EP3583218B1 (https=)
JP (2) JP7288402B2 (https=)
KR (1) KR102595249B1 (https=)
CN (2) CN118634339B (https=)
AU (1) AU2018221171B2 (https=)
CA (1) CA3053534A1 (https=)
ES (1) ES3024357T3 (https=)
WO (1) WO2018152451A1 (https=)

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JP2019508036A (ja) 2016-02-16 2019-03-28 ダナ−ファーバー キャンサー インスティテュート，インコーポレイテッド 免疫療法組成物及び方法
EP3439675A4 (en) 2016-04-08 2019-12-18 Purdue Research Foundation METHOD AND COMPOSITIONS FOR CAR-T CELL THERAPY
US11649288B2 (en) 2017-02-07 2023-05-16 Seattle Children's Hospital Phospholipid ether (PLE) CAR T cell tumor targeting (CTCT) agents
CA3053534A1 (en) * 2017-02-17 2018-08-23 Purdue Research Foundation Targeted ligand-payload based drug delivery for cell therapy
WO2018160622A1 (en) 2017-02-28 2018-09-07 Endocyte, Inc. Compositions and methods for car t cell therapy
US11311576B2 (en) 2018-01-22 2022-04-26 Seattle Children's Hospital Methods of use for CAR T cells
US12312416B2 (en) 2018-02-06 2025-05-27 Seattle Children's Hospital Fluorescein-specific cars exhibiting optimal t cell function against FL-PLE labelled tumors
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