ES2973524T3 - Métodos para mejorar la eficacia de la transducción de vectores en los linfocitos T - Google Patents
Métodos para mejorar la eficacia de la transducción de vectores en los linfocitos T Download PDFInfo
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- ES2973524T3 ES2973524T3 ES20176483T ES20176483T ES2973524T3 ES 2973524 T3 ES2973524 T3 ES 2973524T3 ES 20176483 T ES20176483 T ES 20176483T ES 20176483 T ES20176483 T ES 20176483T ES 2973524 T3 ES2973524 T3 ES 2973524T3
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- C12N2740/15041—Use of virus, viral particle or viral elements as a vector
- C12N2740/15042—Use of virus, viral particle or viral elements as a vector virus or viral particle as vehicle, e.g. encapsulating small organic molecule
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| CN105247042B (zh) | 2013-03-15 | 2021-06-11 | 普林斯顿大学理事会 | 用于高通量纯化的方法和设备 |
| US11493428B2 (en) | 2013-03-15 | 2022-11-08 | Gpb Scientific, Inc. | On-chip microfluidic processing of particles |
| EP3167058B1 (en) * | 2014-07-11 | 2020-05-27 | Celgene Corporation | Methods of improving vector transduction efficiency into t lymphocytes |
| US10976232B2 (en) | 2015-08-24 | 2021-04-13 | Gpb Scientific, Inc. | Methods and devices for multi-step cell purification and concentration |
| CN111065399B (zh) | 2017-09-01 | 2023-11-28 | Gpb科学有限公司 | 使用微流体制备治疗活性细胞的方法 |
| DE102018010282A1 (de) | 2018-01-17 | 2019-07-18 | Immatics US, Inc. | Verfahren zur Feststellung der Wirksamkeit von viralen Vektoren |
| DE102018100967B4 (de) | 2018-01-17 | 2019-08-14 | Immatics US, Inc. | Verfahren zur feststellung der wirksamkeit von viralen vektoren |
| CN108715865B (zh) * | 2018-05-28 | 2021-09-21 | 福建师范大学 | 用于提高细胞转染效率的试剂组合物 |
| WO2021011907A1 (en) | 2019-07-18 | 2021-01-21 | Gpb Scientific, Inc. | Ordered processing of blood products to produce therapeutically active cells |
| JP2023508465A (ja) | 2019-12-28 | 2023-03-02 | ジーピービー・サイエンティフィック・インコーポレイテッド | 粒子および細胞を処理するためのマイクロ流体カートリッジ |
| CN117120597A (zh) * | 2021-04-06 | 2023-11-24 | 北京清辉联诺生物科技有限责任公司 | 提高γδ T细胞病毒转导稳定性的方法及其应用 |
| WO2023286088A1 (en) * | 2021-07-16 | 2023-01-19 | Indian Institute Of Science Education And Research Bhopal | Methods and compositions for viral vector transduction |
| WO2025180499A1 (zh) * | 2024-02-28 | 2025-09-04 | 南京因领生物科技有限公司 | 一种提高细胞中病毒包装产量或质量的方法 |
| CN119530302B (zh) * | 2025-01-22 | 2025-06-27 | 青岛华赛伯曼医学细胞生物有限公司 | 提高til细胞的慢病毒转导效率及转导稳定性的方法及试剂盒 |
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| US6534055B1 (en) | 1988-11-23 | 2003-03-18 | Genetics Institute, Inc. | Methods for selectively stimulating proliferation of T cells |
| US6352694B1 (en) | 1994-06-03 | 2002-03-05 | Genetics Institute, Inc. | Methods for inducing a population of T cells to proliferate using agents which recognize TCR/CD3 and ligands which stimulate an accessory molecule on the surface of the T cells |
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| IL104570A0 (en) | 1992-03-18 | 1993-05-13 | Yeda Res & Dev | Chimeric genes and cells transformed therewith |
| US8211422B2 (en) | 1992-03-18 | 2012-07-03 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Chimeric receptor genes and cells transformed therewith |
| US6692964B1 (en) | 1995-05-04 | 2004-02-17 | The United States Of America As Represented By The Secretary Of The Navy | Methods for transfecting T cells |
| DE69634563T2 (de) * | 1995-05-04 | 2006-02-16 | The United States Of America As Representend By The Secretary Of The Navy | Verbesserte verfahren zur transfektion der t-zellen |
| US5948893A (en) | 1996-01-17 | 1999-09-07 | The United States Of America As Represented By The Secretary Of The Navy | Murine hybridoma and antibody binding to CD28 receptor secreted by the hybridoma and method of using the antibody |
| US5994136A (en) | 1997-12-12 | 1999-11-30 | Cell Genesys, Inc. | Method and means for producing high titer, safe, recombinant lentivirus vectors |
| ATE528406T1 (de) | 1999-04-29 | 2011-10-15 | Gbp Ip Llc | Verfahren und mittel zur herstellung von sicheren,rekombinanten lentivirusvektoren mit hohem titer |
| AU2002251935B2 (en) | 2001-02-14 | 2007-11-29 | Celularity Inc. | Post-partum mammalian placenta, its use and placental stem cells therefrom |
| US20060210536A1 (en) * | 2003-04-17 | 2006-09-21 | Curt Horvath | Methods and compositions for inhibiting stat signaling pathways |
| EP1624899B1 (en) * | 2003-05-05 | 2010-11-17 | VIRxSYS Corporation | INCREASED TRANSDUCTION USING ABC TRANSPORTER SUBSTRATES that are INHIBITORS |
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| WO2008153742A2 (en) | 2007-05-23 | 2008-12-18 | Sangamo Biosciences, Inc. | Methods and compositions for increased transgene expression |
| ES2530995T3 (es) | 2007-09-28 | 2015-03-09 | Anthrogenesis Corp | Supresión de tumor usando perfusato placentario humano y células asesinas naturales intermediarias que provienen de placenta humana |
| ES2749500T3 (es) | 2008-11-19 | 2020-03-20 | Celularity Inc | Células adherentes derivadas del amnios |
| KR20190108599A (ko) | 2010-07-13 | 2019-09-24 | 안트로제네시스 코포레이션 | 천연 킬러 세포의 생성 방법 |
| WO2012072096A1 (en) | 2010-12-03 | 2012-06-07 | Biontech Ag | Method for cellular rna expression |
| PL2820138T3 (pl) * | 2012-02-29 | 2021-04-06 | Helmholtz Zentrum München - Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH) | Retrowirusowa transdukcja z zastosowaniem poloksamerów |
| EA201990959A1 (ru) * | 2012-04-11 | 2020-02-10 | Дзе Юнайтед Стейтс Оф Америка, Эз Репрезентед Бай Дзе Секретари, Департмент Оф Хелс Энд Хьюман Сёрвисез | Химерные антигенные рецепторы, нацеленные на антиген созревания b-клеток |
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| EP3167058B1 (en) * | 2014-07-11 | 2020-05-27 | Celgene Corporation | Methods of improving vector transduction efficiency into t lymphocytes |
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