ES2968816T3 - Detergent composition - Google Patents

Abstract

The present invention is in the field of compositions for machine dishwashers. More particularly, it relates to dishwashing compositions comprising a carbohydrate oxidizing enzyme. The invention also relates to a method for washing kitchen utensils in a dishwasher with a dishwasher composition comprising a carbohydrate oxidizing enzyme and a process for preparing said composition. (Automatic translation with Google Translate, without legal value)

Description

DESCRIPTION

Detergent composition

Technical field of the invention

The present invention is in the field of compositions for machine dishwashing. More particularly, it relates to machine dishwashing compositions comprising carbohydrate oxidase enzymes and a surfactant system. The invention also relates to a method of washing household items in a dishwasher with a machine dishwashing composition comprising carbohydrate oxidase enzymes and to a process for preparing said composition.

Background of the invention

Machine dishwashing compositions comprising bleaching enzymes have been described in the prior art.

WO1999/002640 discloses cleaning compositions comprising oxidoreductase (non-heme haloperoxidase) with an a/p-hydrolase fold and a catalytic triad consisting of the amino acid residues serine, histidine and aspartic acid. Example 19 discloses a dishwashing composition comprising 0.002% by weight haloperoxidase, 1.2% by weight nonionic surfactant, pH 8. Enzymatic dishwashing compositions have poor stain removal power, particularly in the absence of percarbonate and/or perborate. WO94/23637 A1 discloses granular machine dishwashing compositions comprising 1.5% by weight of nonionic surfactant, 10% by weight of glucose and 250 units/gram of glucose oxidase enzyme, which form an enzymatic source of hydrogen peroxide, which have a pH of 10.7. The compositions bleach blackcurrant juice stains and require a bleaching catalyst. Notorious hard-to-remove stains include tea stains, which require substantial bleaching power to remove. There remains a need for dishwashing compositions that are free of metallic bleach catalysts and may be free of bleach precursors (e.g., percarbonate and/or perborate) and more preferably have reduced amounts of, preferably free of, bleach activators. and still provide (tea) stain removal power.

Summary of the invention

The inventors have developed a dishwasher composition which has an excellent (tea) stain removing powder, particularly percarbonate and/or perborate, and under some conditions even shows very good tea stain whitening when free of activator. bleaching and bleaching catalyst. Accordingly, the present invention relates to a dishwasher composition according to claim 1. It will be appreciated that the carbohydrate oxidase enzyme substrate b) is suitable for the carbohydrate oxidase enzyme a) used in the composition according to the invention to act on he. This is so that the system generates adequate amounts of H<2>O<2>. It was surprisingly found that a machine dishwashing composition according to the invention can effectively remove tea stains without the presence of bleach precursor, bleach activator and bleach catalyst at high temperatures. This is all the more surprising since, under such high temperature (and alkaline) conditions, the enzyme system cannot be expected to be able to efficiently generate sufficient H<2>O<2>. Typical optimal enzyme conditions are at low temperatures and/or neutral to slightly acidic pH levels. In fact, the optimal conditions for the enzyme used in the examples were a temperature of 35-40 °C and a pH of 5.2. However, under the conditions of pH 10.5 with a temperature of 80°C, it efficiently generated H<2>O<2>from available glucose and provided excellent removal of tea stains.

Furthermore, it was surprisingly found that a machine dishwashing composition according to the invention can effectively remove tea stains without the presence of bleach precursor and/or bleach activator at low-medium temperatures while using relatively small amounts. active enzyme and bleaching catalyst. The ability to employ relatively small amounts of active enzyme to provide good tea stain removal is highly beneficial from a stability standpoint, from a cost standpoint, as well as from a stability standpoint. of the product.

In a second aspect, the invention also relates to a unit dose comprising a composition defined herein, wherein the unit dose is a gel, powder, liquid or a combination thereof.

In a third aspect, the invention relates to a method of cleaning household items comprising the steps of contacting the composition defined herein with household items in the presence of water, preferably at a temperature in the range of 3° to 90°. c.

In a fourth aspect, the invention relates to a use of a composition according to claim 13.

In a fifth aspect, the invention refers to a process for preparing compositions according to any of the preceding claims that comprises the step of combining a carbohydrate oxidase enzyme, a substrate for said enzyme and a nonionic surfactant system.

Detailed description of the invention

The term "carbohydrate oxidase enzyme", as used herein, preferably refers to an enzyme of the class E.C.1.1.3 and E.C.1.1.3.4, but is otherwise used in the general sense of enzymes that can generate peroxide using a carbohydrate substrate.

The term “comprising,” as used herein, is intended to mean “including” but not necessarily “consisting of,” “composed of.” In other words, the steps or options listed need not be exhaustive.

Unless otherwise specified, numerical ranges expressed in the format “x to y” or “x-y” are intended to include x and y. When multiple preferred intervals are described for a specific characteristic in the format “from x to y” or “x-y”, it is understood that all intervals that combine the different endpoints are also contemplated. For the purpose of the invention, ambient temperature is defined as a temperature of approximately 20°C. Unless otherwise indicated, weight percentages (wt%) are based on the total weight of the composition.

The enzyme, selected from the group of carbohydrate oxidases, can generate hydrogen peroxide. Preferably, the carbohydrate oxidase enzyme is selected from the group consisting of alcohol oxidase, glucose oxidase, galactose oxidase, sorbose oxidase, hexose oxidase, aldose oxidase and mixtures thereof, more preferably glucose oxidase. Suitable oxidase enzymes are those classified under the enzyme classification E.C.1.1.3., specifically those that act on the CH-OH group of donors with oxygen as acceptor. Preferably, the oxidase enzymes are selected from those with the enzyme commission number E.C.1.1.3.4.

In a preferred embodiment, the carbohydrate oxidase enzyme is glucose oxidase, for example, a glucose oxidase available from Sigma Aldrich (UK) under catalog number G7141 (CAS Registry No. 9001-37-0), Roche (GOD) , Sorachim (GLO-202A), Sekisui (HPS300 or Maxapal®GO4 (DSM The Netherlands). Preferably, the glucose oxidase has at least 70%, preferably at least 80%, more preferably at least 90% homology of amino acid sequence with glucose oxidase with accession number P13006 (Uniprot).

Preferably, the enzyme of the invention has its optimal temperature condition in a temperature range of from 25 to 55, more preferably from 30 to 45 and even more preferably from 35 to 40 ° C. Advantageously, the enzyme of the invention has its optimal pH condition in the range of from 4.5 to 8.0, more preferably from 4.6 to 7.0, even more preferably from 4.8 to 6.0 and even more preferably from 5.0 to 5.5. Surprisingly, it was found that an enzyme that can generate peroxide and that has temperature and pH optima in these ranges was able to provide good bleaching of tea stains under MDW washing conditions, even under very alkaline conditions at high temperatures. Such conditions are quite far from the general optimal enzymatic conditions, although good carbohydrate oxidase-based bleaching of tea stains was observed. The amount of carbohydrate oxidase enzyme will depend on its specific activity, but preferably the machine dishwashing composition of the invention comprises from 10 to 5000, preferably from 60 to 2000, more preferably from 100 to 1500 and even more preferably from 200 to 1000 units of carbohydrate oxidase enzyme per 18 g of the composition. One unit of enzyme activity is defined as the amount required to convert 1 |imol of its substrate per minute under conventional conditions. The range of 200 to 1000 carbohydrate oxidase enzyme units was found to be optimal in view of providing good tea stain cleaning and minimizing the amounts of active components used. In fact, it was interestingly observed that very high levels of carbohydrate oxidase enzyme did not by themselves lead to better tea stain removal.

The machine dishwashing composition preferably comprises 0.01 to 0.4% by weight of active carbohydrate oxidase enzyme. More preferably, the machine dishwashing composition comprises from 0.02 to 0.3% by weight of active carbohydrate oxidase enzyme, even more preferably from 0.04 to 0.2% by weight and even more preferably from 0.045 to 0.08% by weight of active carbohydrate oxidase enzyme. Likewise, this latter range was found to provide an optimal balance between good tea stain cleaning and minimization of the amounts of detergent active components required. The amount of active enzyme can generally be equated with the amount of pure enzyme.

Preferably, the carbohydrate oxidase enzyme substrate is selected from the group consisting of allose, altrose, glucose, mannose, gulose, idose, galactose, thallose, sorbose and mixtures thereof, preferably the carbohydrate oxidase enzyme substrate is selected from the group consisting consists of D-(+)-allose, D-(+)-altrose, D-(+)-glucose, D-(+)-mannose, D-(-)-gulose, D-(+)-idose, D-(+)-galactose, D-(+)-thallose and mixtures thereof. More preferably, the carbohydrate oxidase enzyme substrate is selected from the group consisting of glucose, galactose, sorbose and mixtures thereof. In certain preferred embodiments, the carbohydrate oxidase enzyme substrate is selected from the group consisting of D-glucose, 2-deoxy-D-glucose, 4-O-methyl-D-glucose, 6-deoxy-D-glucose, 4- deoxy-D-glucose, 3-deoxy-D-glucose, 3-O-methyl-D-glucose and mixtures thereof.

The composition of the invention preferably comprises from 2 to 35% by weight, more preferably from 5 to 33% by weight, even more preferably from 10 to 30% by weight and even more preferably from 11 to 30% by weight. 25% by weight of the carbohydrate substrate. Such carbohydrate substrate levels were found to be more optimal for tea stain removal, especially at low-medium temperatures.

The surfactant system comprises nonionic surfactant. Preferably, the composition comprises anionic surfactants, cationic surfactants and amphoteric/zwitterionic surfactants, and mixtures thereof.

In general, the nonionic and/or anionic surfactants of the surfactant system can be chosen from the surfactants described in “Surface Active Agents”, vol. 1 of Schwartz and Perry, Interscience 1949, vol. 2 of Schwartz, Perry and Berch, InterScience 1958, in the current edition of “McCutcheon's Emulsifiers and Detergents” published by Manufacturing Confectioners Company or in “Tenside-Taschenbuch”, H. Stache, 2nd ed., Carl Hauser Verlag, 1981. Suitable nonionic detergent compounds that can be used include, in particular, the reaction products of compounds having a hydrophobic group and a reactive hydrogen atom, for example, aliphatic alcohols, acids, amides or alkylphenols with alkylene oxides, especially carbon dioxide. ethylene either alone or with propylene oxide. Specific nonionic detergent compounds are ethylene oxide-alkylphenol C-C condensates, generally 5 to 25 EO, that is, 5 to 25 ethylene oxide units per molecule, and the condensation products of linear or branched aliphatic alcohols Cs- Primary or secondary Cs with ethylene oxide, generally 5 to 40 OE.

In a preferred embodiment, the machine dishwashing composition comprises a system of nonionic surfactants selected from a C10-20 fatty acid, an alkoxylated fatty alcohol, an alkoxylated fatty acid, alkylphenol alkoxylates, alkoxylated amines, fatty acid amides alkoxylates, terminally blocked alkoxylates, glycerol fatty acid esters, sorbitol fatty acid esters, sucrose fatty acid esters, alkylpolyglucosides, amine oxides, sulfoxides, phosphine oxides, more preferably selected from a C10-20 fatty acid, an ethoxylated fatty alcohol, an ethoxylated fatty acid, alkylphenol ethoxylates, ethoxylated amines, ethoxylated fatty acid amides, terminally blocked ethoxylates, glycerol fatty acid esters, sorbitol fatty acid esters, sucrose fatty acid esters, alkylpolyglucosides, amine oxides, sulfoxides, phosphine oxides.

Preferably, the machine dishwashing composition comprises from 0.1 to 15% by weight of nonionic surfactant, preferably from 1.0 to 12.0% by weight of nonionic surfactant, more preferably from 2.0 8% by weight of nonionic surfactant, most preferably 2.5 to 5% by weight of nonionic surfactant.

Preferably, the machine dishwashing composition comprises at most 5.0% by weight, more preferably at most 4.0% by weight, even more preferably at most 3.0% by weight, even more preferably at most 2.0% by weight and even more preferably at most 1.0% by weight of anionic surfactant.

The machine dishwashing composition preferably comprises 10 to 50% by weight of carbonate salts, preferably selected from Na<2>CO<3>, K<2>CO<3>, CaCO<3>or a combination thereof, preferably 15 to 40% by weight of carbonate salts selected from Na<2>CO<3>and CaCO<3>or a combination of both, most preferably 20 to 30% by weight of carbonate, selected from Na<2>CO<3>, CaCO<3>or a combination of both. In a preferred embodiment, the carbonate salt is Na<2>CO<3>.

The term "adjuvant", as used herein, refers to a material that can remove calcium and/or magnesium ions from an aqueous solution by ion exchange, complexation, sequestration and/or precipitation. Preferably, the adjuvant or sequestering material is completely soluble in water to eliminate the possibility of unwanted and unsightly residues on the substrates. For this reason, alkali metal aluminosilicates are not preferred. Typical examples of inorganic phosphorus-containing adjuvants, when present, include water-soluble salts, especially alkali metal pyrophosphates, orthophosphates and polyphosphates. Specific examples of inorganic phosphate builders include sodium and potassium tripolyphosphates, pyrophosphates, and hexametaphosphates. Examples of suitable non-phosphorus water-soluble detergency builders, when present, include carbonate, citrate, zeolite, silicate and aminopolycarboxylic compounds, such as glutamatediacetic acid (GLDA), methylglycinodiacetic acid (MGDA) and trisodium citrate. Other non-phosphorus water-soluble builders may include inorganic builders such as alkali metal carbonates, bicarbonates, sesquicarbonates, borates, silicates, metasilicates and amorphous alkali metal aluminosilicates, and organic builders such as polycarboxylate polymers, such as polyacrylates, acrylic copolymers /maleic and acrylic phosphonates, monomeric polycarboxylates such as citrates, gluconates, oxydisuccinates, glycerol mono, di and trisuccinates, carboxymethyloxysuccinates, carboxymethyloxymalonates, dipicolinates and hydroxyethyliminodiacetates.

bleaching activator

The term “bleach activator,” as used herein, refers to compounds used in cleaning compositions to activate the bleaching agent, or bleach component, especially at lower temperatures. Examples of bleach activators suitable for use in the cleaning compositions of this invention include one or more activators such as peroxyacid bleach precursors. Peroxyacid bleach precursors are well known in the art. Non-limiting examples include tetraacetylethylenediamine (TAED), sodium nonanoyloxybenzenesulfonate (SNOBS), sodium benzoyloxybenzenesulfonate (SBOBS) and the precursor of cationic peroxyacid (SPCC). These and other related compounds are described in more detail by Grime and Clauss in Chemistry & Industry (October 15, 1990) 647 653. The detergent composition of the invention may comprise from 0.01 to 15% by weight of activator bleach, more preferably from 0.2 to 10% by weight and even more preferably from 1.0 to 6% by weight, but more preferably it does not comprise bleach activator.

bleaching catalyst

Bleaching catalysts typically work by oxidation through peroxide or a peracid to form a bleaching species. They require the presence of an oxidizable soil so that they can be reduced back to the starting bleach activator state.

The bleaching catalyst may be a manganese complex of formula (A):

[L<n>Mn<m>X<p>]<z>Yq,

wherein Mn is manganese, which may be in oxidation state II, III, IV or V, or mixtures thereof; n and m are independent integers 1-4; X represents a kind of coordination or bridge; p is an integer from 0-12; Y is a counterion, whose type depends on the z charge of the complex, which can be positive, zero or negative; q = z/[charge Y]; and L is a ligand that is a macrocyclic organic molecule of the general formula:

wherein each of R1 and R2 may be zero, H, alkyl or optionally substituted aryl; each of t and t' are independent integers of 2-3; each D may independently be N, NR, PR, O or S, where R is H, alkyl or optionally substituted aryl; and s is an integer from 2-5.

Such bleaching catalysts are described in EP0458397A2.

Bleaching catalysts may be one or more of:

• [Mn<III2>(^-O)1 (^-OAc)<2>(TACN)<2>] (ClO4)2;

• [MnIIIMnIV (^-O)<2>^-OAc<)1>(TACN)<2>] (BPh4)2;

• [MnIV4 (^-O)6 (TACN)4] (ClO4)4;

• [Mn<m2>(|i-O), (|i-OAc<)2>(Me-TACN)<2>] (ClO4)2;

• [MnmMnIV (|i-O<)1>(|i-OAc<)2>(Me-TACN)<2>] (PF<6>)<2>;

• [Mn<IV2>(|i-O)a (Me/Me-TACN)<2>] (PF<6)2>;

• [MnmMnIV(|i-O)<2>(|i-OAc)i (Me-TACN)<2>] (BPh4)2;

• [MnIV<2>(^-O)a(Me-TACN)<2>] (PF<6>)<2>;

• [Mnm<2>(^-O)i(u-OAc)<2>(Me-TACN)<2>] (ClO4)2; and

• [MnmMnIV4(|i-O)i(|i-OAc)2(Me-TACN)2] (ClO4)3.

wherein 1,4,7-trimethyl-1,4,7-triazacyclononane is encoded as Me-TACN; 1,4,7-triazacidononane is encoded as TACN; 1,5,9-trimethyl-1,5,9-triazacidododecane is encoded as Me-TACD; 2-methyl-1,4,7-trimethyl-1,4,7-triazacyclononane is encoded as Me/Me-TACN; and 2-methyl-1,4,7-triazacyclononane is encoded as Me/TACN. The bleach catalyst may be part of a bleach catalyst granule comprising less than 5% by weight of active bleach catalyst. The use of such granules improves the precise dosage of the bleaching catalyst.

The detergent composition is preferably a powder, a tablet, an aqueous or non-aqueous liquid, a loose fluid powder, a paste, a capsule or a gel. Preferably, the composition is in the form of a gel, a capsule or a tablet, more preferably a capsule.

The carbohydrate oxidase enzyme used in the present invention can usefully be added to the detergent composition in any suitable form, that is, in the form of a granular composition, a liquid or a suspension of the enzyme, or with carrier material. For example, the addition of the enzyme to a liquid detergent product is in the form of a suspension containing 0.5 to 50% by weight of the enzyme in an ethoxylated alcohol nonionic surfactant, as described in the document EP-A-450702 (Unilever).

In a preferred embodiment wherein the machine dishwashing composition is a fluid or solid powder, the machine dishwashing composition preferably has a water content of less than 5% by weight. An even more preferred embodiment is one in which the machine dishwashing composition is a tablet with a water content of less than 5% by weight.

Preferably, a 1% by weight solution of the detergent composition in deionized water has a pH in the range of 8.5 - 11.0, more preferably 9.0 - 10.75 and most preferably 9.5 - 10.5. The pH is measured at 25 °C, under otherwise conventional conditions.

The composition may be in the form of a unit dose, wherein the unit dose is a gel, powder, liquid or a combination thereof.

Given the above, a preferred machine dishwashing composition according to the invention comprises: a) from 0.02 to 0.3% by weight of active carbohydrate oxidase enzyme, preferably selected from the group consisting of alcohol oxidase, glucose oxidase, galactose oxidase, sorbose oxidase, hexose oxidase, aldose oxidase and mixtures thereof, more preferably glucose oxidase;

b) from 10 to 30% by weight of the carbohydrate oxidase enzyme substrate and

c) a surfactant system comprising nonionic surfactant,

wherein the pH of a 1% by weight solution of the composition in deionized water is in the range of from 8.5 to 11.0, as measured at 25 ° C and under otherwise conventional conditions, in which the composition is free of metallic bleaching catalyst.

Given the above, an even more preferred machine dishwashing composition according to the invention for use at a washing temperature greater than 65 ° C comprises:

a) from 0.04 to 0.2% by weight of active carbohydrate oxidase enzyme, preferably selected from the group consisting of alcohol oxidase, glucose oxidase, galactose oxidase, sorbose oxidase, hexose oxidase, aldose oxidase and mixtures thereof , more preferably glucose oxidase;

b) from 10 to 25% by weight of the carbohydrate oxidase enzyme substrate and

c) a surfactant system comprising nonionic surfactant,

wherein the pH of a 1% by weight solution of the composition in deionized water is in the range of from 8.5 to 11.0, as measured at 25 ° C and under otherwise conventional conditions; wherein little or no bleach activator and bleach catalyst is present, wherein the composition is free of metallic bleach catalyst.

The machine dishwashing compositions of the invention preferably do not comprise bleach precursor, although the presence thereof does not negatively affect the cleaning of tea stains.

In a second aspect, a method of cleaning household items is provided comprising the steps of contacting a detergent composition as defined herein with household items in the presence of water. Preferably, the method is carried out at a temperature in the range of 30 to 90°C, more preferably 40 to 85°C, even more preferably 50 to 80°C. High temperature washing conditions are defined as using a temperature above 65°C; Low-medium temperature washing conditions such as a maximum temperature of 65 °C.

The components and quantities of components described herein are applied with necessary changes to the second aspect.

The components and quantities of components described herein are applied with necessary changes to the third aspect.

Preferably, the stain remover is active at a temperature in the range of 40 to 90°C, more preferably 40 to 85°C, even more preferably 50 to 80°C.

In a fourth aspect, there is provided a method of preparing compositions as described herein comprising the step of combining a carbohydrate oxidase enzyme, a substrate for said enzyme and a nonionic surfactant system.

In a fifth aspect, a procedure for preparing a unit dose according to any of the preceding claims is provided, comprising the step of:

Yo. providing a carbohydrate oxidase enzyme, a substrate for said enzyme and a nonionic surfactant system to provide a mixture,

ii. conform the mixture of step (i) to give a unit dose.

The components and quantities of components described herein are applied with necessary changes to the fourth and fifth aspects.

Examples

General methods/reagents used

Compositions 1-3, 6, 7 and A are not according to the claims and are for illustrative purposes.

Example 1

The following compositions (1-5 and comparative A) were prepared, as shown in Table 1:

Table 1

The following compositions 6 to 8 were prepared, as shown in Table 2:

Example 2

Stained slabs (DM-14 post-fermented tea on melamine; supplier: Center for Materials Testing B.V.) were placed in a 5 L solution prepared from the dosage of 18 g according to the formulations listed in Table 1 in water. Each solution was placed in a beaker with stirring and controlled temperature for 20 min. The temperature was as indicated in table 3. Scale: stain removal power from (-) poor to (+++) best:

Table 3

Claims (15)

1. Composition for dishwashers comprising: a) from 0.002 to 0.5% by weight of active carbohydrate oxidase enzyme, preferably selected from the group consisting of alcohol oxidase, glucose oxidase, galactose oxidase, sorbose oxidase, hexose oxidase, aldose oxidase and mixtures thereof, more preferably glucose oxidase; b) from 1 to 40% by weight of the carbohydrate oxidase enzyme substrate and c) a surfactant system comprising nonionic surfactant, wherein the pH of a 1% by weight solution of the composition in deionized water is in the range of from 8.5 to 11.5, as measured at 25 ° C and under otherwise conventional conditions, wherein the composition is free of metallic bleaching catalyst. 2. Composition according to claim 1, wherein the composition comprises 0.01 to 0.4% by weight of active carbohydrate oxidase enzyme, preferably 0.02 to 0.3% by weight of carbohydrate oxidase enzyme, more preferably from 0.04 to 0.2% by weight and even more preferably from 0.045 to 0.08% by weight of active carbohydrate oxidase enzyme. 3. Composition according to claims 1 or 2, wherein the carbohydrate oxidase enzyme is a glucose oxidase from Aspergillus niger. 4. Composition according to claim 3, wherein the carbohydrate oxidase enzyme substrate is glucose. 5. Composition according to any of the preceding claims, comprising from 2 to 35% by weight, preferably from 5 to 33% by weight, more preferably from 10 to 30% by weight of the carbohydrate source and even more preferably from 11 to 25% by weight of the carbohydrate source. 6. Composition according to any of the preceding claims, wherein the surfactant system comprises from 1.0 to 15.0% by weight of nonionic surfactant, more preferably from 2.0 to 10% by weight, the most preferably 2.5 to 5% by weight. 7. Composition according to any of the preceding claims, wherein the composition comprises a nonionic surfactant system selected from a C10-20 fatty acid, an alkoxylated fatty alcohol, an alkoxylated fatty acid, alkylphenol alkoxylates, alkoxylated amines, alkoxylated fatty acid amides, terminally blocked alkoxylates, glycerol fatty acid esters, sorbitol fatty acid esters, sucrose fatty acid esters, alkylpolyglucosides, amine oxides, sulfoxides, phosphine oxides, more preferably selected from a fatty acid C10-20, an ethoxylated fatty alcohol, an ethoxylated fatty acid, alkylphenol ethoxylates, ethoxylated amines, ethoxylated fatty acid amides, terminally blocked ethoxylates, glycerol fatty acid esters, sorbitol fatty acid esters, sorbitol fatty acid esters sucrose, alkylpolyglucosides, amine oxides, sulfoxides, phosphine oxides. 8. Composition according to any of the preceding claims, composition comprising 10 to 50% by weight of water-soluble alkali metal carbonate, preferably the water-soluble alkali metal carbonate is selected from Na<2>CO<3>, K<2>CO<3>and CaCO<3>, and combinations thereof. 9. Composition according to any of the preceding claims, wherein a 1% by weight solution of the composition in deionized water has a pH in the range of 8.5 - 11.0, preferably 9.0 - 10.75 and more preferably 9.5 - 10.5, as measured at 25°C. 10. Composition according to any of the preceding claims, wherein the composition is in the form of a gel, a powder, an aqueous or non-aqueous liquid. 11. Unit dose comprising a composition according to any of the preceding claims, wherein the unit dose is a gel, powder, liquid or a combination thereof. 12. Method of cleaning household items comprising the steps of contacting the composition according to any of claims 1-10 or the unit dose according to claim 11 with household items in the presence of water, preferably at a temperature in the range of 30 to 90°C. 13. Use of a composition according to any of claims 1-10 or a unit dose according to claim 11 as a tea stain remover, preferably as a sustainable/bio-based/eco-friendly tea stain remover, wherein more preferably the Stain remover is active at a temperature in the range of 30 to 90°C, more preferably 40 to 90°C and even more preferably 50 to 80°C. 14. Procedure for preparing compositions according to any of claims 1-10, which comprises the step of combining a carbohydrate oxidase enzyme, a substrate for said enzyme and a nonionic surfactant system. 15. Procedure for preparing a unit dose according to claim 11: Yo. providing a carbohydrate oxidase enzyme, a substrate for said enzyme and a nonionic surfactant system to provide a mixture, ii. conform the mixture of step (i) to give a unit dose.