ES296859A1 - Procedure for the manufacture of new phenyl-ciclohexilalquilaminas and their salts (Machine-translation by Google Translate, not legally binding)
- Google Patents
Procedure for the manufacture of new phenyl-ciclohexilalquilaminas and their salts (Machine-translation by Google Translate, not legally binding)
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Roche Diagnostics GmbH
CF Boehringer und Soehne GmbH
Original Assignee
Boehringer Mannheim GmbH
CF Boehringer und Soehne GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Mannheim GmbH, CF Boehringer und Soehne GmbHfiledCriticalBoehringer Mannheim GmbH
Publication of ES296859A1publicationCriticalpatent/ES296859A1/en
Organic Low-Molecular-Weight Compounds And Preparation Thereof
(AREA)
Abstract
Process for the manufacture of new phenylcyclohexylalkylamines and their salts, characterized in that starting from the general formula I ** (See formula) ** wherein R 1 signifies hydrogen or a lower alkyl moiety, R 2 and R 3 hydrogen, hydroxy, alkoxy, methylenedioxy or aralkoxy moieties, and n is equal to 2 or 3, or, amines of the general formula II are reduced ** (See formula) ** wherein R1 and n have the meaning mentioned above, together with phenylpropanones of the general formula III ** (See formula) ** wherein R2 and R3 have the meaning indicated above, or amines of the general formula II are reacted with a halogenide of the formula IV ** (See formula) ** wherein R 2 and R 3 have the meaning indicated above, optionally in the presence of halogenated hydrocarbon linking media, or amides of the general formula V are reacted ** (See formula) ** wherein R1, R2 and R3 have the above meaning, with a halogenide of the general formula VI ** (See formula) ** wherein n has the meaning indicated above, if appropriate in the presence of hydrogen halide linking means, or organic acid amides of the general formula VII ** (See formula) ** in which R1, R2 and R3 and n have the meaning indicated above, they are reduced to the corresponding amines, after which, if any, the compounds obtained-provided that R1 means a hydrogen atom-are alkylated as usual in nitrogen, or else - if R2 and R3 mean alkoxy or aralkoxy groups - they are converted as usual into the corresponding hydroxy compounds and if it is of interest they are transferred to their salts. (Machine-translation by Google Translate, not legally binding)
ES0296859A1963-02-261964-02-25Procedure for the manufacture of new phenyl-ciclohexilalquilaminas and their salts (Machine-translation by Google Translate, not legally binding)
ExpiredES296859A1
(en)
Procedure for preparing N-alcohilamino-alcohilic derivatives of espirotetralinosuccinimidas and their salts. (Machine-translation by Google Translate, not legally binding)
Procedure for the obtaining of amidas from the acid 1,6-dimetildelta-8,9-ergolen-8-carboxilico. (Machine-translation by Google Translate, not legally binding)