Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Societe Industrielle pour la Fabrication des Antibiotiques SA SIFA
Original Assignee
Societe Industrielle pour la Fabrication des Antibiotiques SA SIFA
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Publication date
Priority claimed from FR924307Aexternal-prioritypatent/FR1356997A/en
Priority claimed from FR933521Aexternal-prioritypatent/FR2857M/en
Application filed by Societe Industrielle pour la Fabrication des Antibiotiques SA SIFAfiledCriticalSociete Industrielle pour la Fabrication des Antibiotiques SA SIFA
Publication of ES295227A1publicationCriticalpatent/ES295227A1/en
A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
A61K31/00—Medicinal preparations containing organic active ingredients
A61K31/65—Tetracyclines
Abstract
Preparation process of the tetracycline alcohol sulphates whose alkyl radical comprises at most 4 carbon atoms, characterized by contacting an ion-exchange resin of the cationic type with an alkali alcohol sulphate in solution in isopropanol, said alcohol sulfate comprising at most 4 atoms of carbon, then the sulfuric acid thus obtained is made to act on tetracycline base in isopropanol medium, the products are then left in contact with stirring and finally the tetracycline alcohol sulphate formed in solution is isolated by drying the solvent or addition precipitation to the reaction medium of a liquid in which the desired product is insoluble. (Machine-translation by Google Translate, not legally binding)
ES295227A1963-02-111964-01-11Procedure for preparation of tetracycline alcohilules (Machine-translation by Google Translate, not legally binding)
ExpiredES295227A1
(en)