ES2927760T8 - Esteres halogenados de ácidos grasos insaturados ciclopropanados para su utilización en el tratamiento de las enfermedades neurodegenerativas - Google Patents
Esteres halogenados de ácidos grasos insaturados ciclopropanados para su utilización en el tratamiento de las enfermedades neurodegenerativasInfo
- Publication number
- ES2927760T8 ES2927760T8 ES19164672T ES19164672T ES2927760T8 ES 2927760 T8 ES2927760 T8 ES 2927760T8 ES 19164672 T ES19164672 T ES 19164672T ES 19164672 T ES19164672 T ES 19164672T ES 2927760 T8 ES2927760 T8 ES 2927760T8
- Authority
- ES
- Spain
- Prior art keywords
- cyclopropanated
- treatment
- fatty acids
- unsaturated fatty
- neurodegenerative diseases
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
- A61K31/23—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
- A61K31/202—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids having three or more double bonds, e.g. linolenic
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/336—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having three-membered rings, e.g. oxirane, fumagillin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/62—Halogen-containing esters
- C07C69/63—Halogen-containing esters of saturated acids
- C07C69/635—Halogen-containing esters of saturated acids containing rings in the acid moiety
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2602/00—Systems containing two condensed rings
- C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Organic Chemistry (AREA)
- Epidemiology (AREA)
- Emergency Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Diabetes (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Hematology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361892727P | 2013-10-18 | 2013-10-18 | |
| US201361896735P | 2013-10-29 | 2013-10-29 | |
| US201461925441P | 2014-01-09 | 2014-01-09 | |
| US201461925449P | 2014-01-09 | 2014-01-09 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES2927760T3 ES2927760T3 (es) | 2022-11-10 |
| ES2927760T8 true ES2927760T8 (es) | 2023-05-05 |
Family
ID=51846995
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES19164672T Active ES2927760T3 (es) | 2013-10-18 | 2014-10-20 | Esteres halogenados de ácidos grasos insaturados ciclopropanados para su utilización en el tratamiento de las enfermedades neurodegenerativas |
| ES14793391T Active ES2732153T3 (es) | 2013-10-18 | 2014-10-20 | Esteres halogenados de ácidos grasos insaturados ciclopropanados para su utilización en el tratamiento de las enfermedades neurodegenerativas |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES14793391T Active ES2732153T3 (es) | 2013-10-18 | 2014-10-20 | Esteres halogenados de ácidos grasos insaturados ciclopropanados para su utilización en el tratamiento de las enfermedades neurodegenerativas |
Country Status (9)
| Country | Link |
|---|---|
| US (4) | US9962357B2 (es) |
| EP (3) | EP4101835A1 (es) |
| JP (1) | JP2016535012A (es) |
| CA (1) | CA2927675A1 (es) |
| DK (1) | DK3057934T3 (es) |
| ES (2) | ES2927760T3 (es) |
| PL (1) | PL3057934T3 (es) |
| PT (1) | PT3057934T (es) |
| WO (1) | WO2015058191A1 (es) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2017062924A1 (en) * | 2015-10-08 | 2017-04-13 | Alkon Daniel L | Dosing regimens of pkc activators |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MY118354A (en) * | 1995-05-01 | 2004-10-30 | Scarista Ltd | 1,3-propane diol derivatives as bioactive compounds |
| JPH10139735A (ja) * | 1996-09-13 | 1998-05-26 | Sumitomo Chem Co Ltd | エステル化合物、それを有効成分とする有害生物防除剤およびその製造中間体 |
| AU2001235363A1 (en) * | 2000-02-25 | 2001-09-03 | Novo-Nordisk A/S | Mibefradil analogues and their use |
| JP4995423B2 (ja) | 2002-12-03 | 2012-08-08 | ブランシェット・ロックフェラー・ニューロサイエンスィズ・インスティテュート | 物質を血液−脳関門を渡って輸送するための人工低密度リポタンパク質キャリア |
| MXPA05009459A (es) * | 2003-03-03 | 2006-05-17 | Array Biopharma Inc | Inhibidores de p38 y sus metodos de uso. |
| DE10351087A1 (de) * | 2003-10-31 | 2005-05-25 | Bayer Technology Services Gmbh | Feste Wirkstoff-Formulierung |
| CN101223884B (zh) * | 2007-01-15 | 2011-07-13 | 大日本除虫菊株式会社 | 杀虫防虫剂或害虫的摄食阻碍剂 |
| ES2683021T3 (es) | 2008-07-28 | 2018-09-24 | Blanchette Rockefeller Neurosciences Institute | Compuestos activadores de la PKC para el tratamiento de enfermedades neurodegenerativas |
| CN101608402B (zh) * | 2009-07-14 | 2011-07-27 | 东华大学 | 植物油改性含氟拒水整理剂、制备方法及其应用 |
| US10052299B2 (en) * | 2009-10-30 | 2018-08-21 | Retrotope, Inc. | Alleviating oxidative stress disorders with PUFA derivatives |
| WO2012137225A1 (en) * | 2011-04-08 | 2012-10-11 | Sphaera Pharma Pvt. Ltd | Substituted methylformyl reagents and method of using same to modify physicochemical and/or pharmacokinetic properties of compounds |
| WO2012148891A1 (en) * | 2011-04-29 | 2012-11-01 | Evonik Degussa Corporation | Peptide-lipid conjugates and uses thereof |
| EP2780316B1 (en) | 2011-11-13 | 2020-04-15 | Blanchette Rockefeller Neurosciences Institute | Esters of dcpla and methods of treatment using the same |
-
2014
- 2014-10-20 CA CA2927675A patent/CA2927675A1/en not_active Abandoned
- 2014-10-20 PL PL14793391T patent/PL3057934T3/pl unknown
- 2014-10-20 EP EP22184036.6A patent/EP4101835A1/en active Pending
- 2014-10-20 WO PCT/US2014/061368 patent/WO2015058191A1/en active Application Filing
- 2014-10-20 EP EP14793391.5A patent/EP3057934B1/en active Active
- 2014-10-20 ES ES19164672T patent/ES2927760T3/es active Active
- 2014-10-20 US US15/028,487 patent/US9962357B2/en active Active
- 2014-10-20 JP JP2016524133A patent/JP2016535012A/ja active Pending
- 2014-10-20 DK DK14793391.5T patent/DK3057934T3/da active
- 2014-10-20 ES ES14793391T patent/ES2732153T3/es active Active
- 2014-10-20 PT PT14793391T patent/PT3057934T/pt unknown
- 2014-10-20 EP EP19164672.8A patent/EP3567025B8/en active Active
-
2018
- 2018-04-04 US US15/945,041 patent/US20180325856A1/en not_active Abandoned
-
2019
- 2019-01-25 US US16/257,988 patent/US11273139B2/en active Active
-
2022
- 2022-02-04 US US17/665,033 patent/US12016837B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| EP3057934A1 (en) | 2016-08-24 |
| EP3567025B1 (en) | 2022-08-03 |
| ES2927760T3 (es) | 2022-11-10 |
| ES2732153T3 (es) | 2019-11-20 |
| US9962357B2 (en) | 2018-05-08 |
| US11273139B2 (en) | 2022-03-15 |
| PL3057934T3 (pl) | 2019-09-30 |
| JP2016535012A (ja) | 2016-11-10 |
| US20180325856A1 (en) | 2018-11-15 |
| US12016837B2 (en) | 2024-06-25 |
| EP4101835A1 (en) | 2022-12-14 |
| PT3057934T (pt) | 2019-06-28 |
| US20220151973A1 (en) | 2022-05-19 |
| DK3057934T3 (da) | 2019-07-01 |
| CA2927675A1 (en) | 2015-04-23 |
| WO2015058191A1 (en) | 2015-04-23 |
| US20190192471A1 (en) | 2019-06-27 |
| EP3567025A1 (en) | 2019-11-13 |
| EP3567025B8 (en) | 2023-01-25 |
| EP3057934B1 (en) | 2019-03-27 |
| US20160256427A1 (en) | 2016-09-08 |
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