ES2918374T3 - Dispositivo de filtración de fluidos y ensamblaje - Google Patents
Dispositivo de filtración de fluidos y ensamblaje Download PDFInfo
- Publication number
- ES2918374T3 ES2918374T3 ES14789265T ES14789265T ES2918374T3 ES 2918374 T3 ES2918374 T3 ES 2918374T3 ES 14789265 T ES14789265 T ES 14789265T ES 14789265 T ES14789265 T ES 14789265T ES 2918374 T3 ES2918374 T3 ES 2918374T3
- Authority
- ES
- Spain
- Prior art keywords
- refining
- fluid
- layer
- flow
- barrier
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- 239000012530 fluid Substances 0.000 title claims abstract description 97
- 238000001914 filtration Methods 0.000 title description 15
- 238000007670 refining Methods 0.000 claims abstract description 113
- 238000000926 separation method Methods 0.000 claims abstract description 24
- 230000004888 barrier function Effects 0.000 claims description 34
- 238000011144 upstream manufacturing Methods 0.000 claims description 4
- 230000009467 reduction Effects 0.000 claims description 3
- 238000004891 communication Methods 0.000 claims description 2
- 239000002245 particle Substances 0.000 description 38
- 239000012528 membrane Substances 0.000 description 12
- 238000005516 engineering process Methods 0.000 description 6
- 210000004027 cell Anatomy 0.000 description 5
- 238000004519 manufacturing process Methods 0.000 description 4
- 239000000463 material Substances 0.000 description 4
- 238000000034 method Methods 0.000 description 4
- 238000005119 centrifugation Methods 0.000 description 3
- 239000007788 liquid Substances 0.000 description 3
- 230000008569 process Effects 0.000 description 3
- 238000004458 analytical method Methods 0.000 description 2
- 230000000712 assembly Effects 0.000 description 2
- 238000000429 assembly Methods 0.000 description 2
- 150000002500 ions Chemical class 0.000 description 2
- 238000002032 lab-on-a-chip Methods 0.000 description 2
- 230000000149 penetrating effect Effects 0.000 description 2
- 239000007787 solid Substances 0.000 description 2
- 101100234408 Danio rerio kif7 gene Proteins 0.000 description 1
- 101100221620 Drosophila melanogaster cos gene Proteins 0.000 description 1
- 239000004642 Polyimide Substances 0.000 description 1
- 101100007330 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) COS2 gene Proteins 0.000 description 1
- 101100398237 Xenopus tropicalis kif11 gene Proteins 0.000 description 1
- 210000000601 blood cell Anatomy 0.000 description 1
- 238000006243 chemical reaction Methods 0.000 description 1
- 239000012141 concentrate Substances 0.000 description 1
- 238000011109 contamination Methods 0.000 description 1
- 238000010168 coupling process Methods 0.000 description 1
- 230000003247 decreasing effect Effects 0.000 description 1
- 235000012489 doughnuts Nutrition 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 230000005684 electric field Effects 0.000 description 1
- 238000005530 etching Methods 0.000 description 1
- 239000000835 fiber Substances 0.000 description 1
- 238000005194 fractionation Methods 0.000 description 1
- 238000002955 isolation Methods 0.000 description 1
- 230000007246 mechanism Effects 0.000 description 1
- 239000002184 metal Substances 0.000 description 1
- 238000005459 micromachining Methods 0.000 description 1
- 238000002156 mixing Methods 0.000 description 1
- 238000011275 oncology therapy Methods 0.000 description 1
- 229920001721 polyimide Polymers 0.000 description 1
- 239000011148 porous material Substances 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 229920002994 synthetic fiber Polymers 0.000 description 1
- 239000004758 synthetic textile Substances 0.000 description 1
- 239000004753 textile Substances 0.000 description 1
- 238000000108 ultra-filtration Methods 0.000 description 1
- 239000013598 vector Substances 0.000 description 1
- 239000002699 waste material Substances 0.000 description 1
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
- B01L3/502715—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by interfacing components, e.g. fluidic, electrical, optical or mechanical interfaces
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
- B01L3/502746—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by the means for controlling flow resistance, e.g. flow controllers, baffles
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
- B01L3/502753—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by bulk separation arrangements on lab-on-a-chip devices, e.g. for filtration or centrifugation
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
- B01L3/502761—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip specially adapted for handling suspended solids or molecules independently from the bulk fluid flow, e.g. for trapping or sorting beads, for physically stretching molecules
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/06—Fluid handling related problems
- B01L2200/0647—Handling flowable solids, e.g. microscopic beads, cells, particles
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/06—Fluid handling related problems
- B01L2200/0647—Handling flowable solids, e.g. microscopic beads, cells, particles
- B01L2200/0652—Sorting or classification of particles or molecules
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/06—Auxiliary integrated devices, integrated components
- B01L2300/0681—Filter
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0809—Geometry, shape and general structure rectangular shaped
- B01L2300/0816—Cards, e.g. flat sample carriers usually with flow in two horizontal directions
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
- B01L2300/0864—Configuration of multiple channels and/or chambers in a single devices comprising only one inlet and multiple receiving wells, e.g. for separation, splitting
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/08—Regulating or influencing the flow resistance
- B01L2400/084—Passive control of flow resistance
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/08—Regulating or influencing the flow resistance
- B01L2400/084—Passive control of flow resistance
- B01L2400/086—Passive control of flow resistance using baffles or other fixed flow obstructions
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Clinical Laboratory Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Dispersion Chemistry (AREA)
- Analytical Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Hematology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Fluid Mechanics (AREA)
- Physics & Mathematics (AREA)
- Molecular Biology (AREA)
- Separation Of Solids By Using Liquids Or Pneumatic Power (AREA)
- Physical Or Chemical Processes And Apparatus (AREA)
- Extraction Or Liquid Replacement (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Sampling And Sample Adjustment (AREA)
- Micromachines (AREA)
- Electrical Discharge Machining, Electrochemical Machining, And Combined Machining (AREA)
- Separation Using Semi-Permeable Membranes (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| NO20131411A NO342032B1 (no) | 2013-10-25 | 2013-10-25 | Fluidraffineringsanordning og -sammenstilling |
| PCT/EP2014/072823 WO2015059264A1 (en) | 2013-10-25 | 2014-10-24 | Fluid filtering device and assembly |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2918374T3 true ES2918374T3 (es) | 2022-07-15 |
Family
ID=51794875
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES14789265T Active ES2918374T3 (es) | 2013-10-25 | 2014-10-24 | Dispositivo de filtración de fluidos y ensamblaje |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US10926259B2 (enExample) |
| EP (1) | EP3060342B1 (enExample) |
| JP (1) | JP6412146B2 (enExample) |
| CN (1) | CN105848782B (enExample) |
| BR (1) | BR112016009218B1 (enExample) |
| CA (1) | CA2928610C (enExample) |
| DK (1) | DK3060342T3 (enExample) |
| ES (1) | ES2918374T3 (enExample) |
| HU (1) | HUE059469T2 (enExample) |
| LT (1) | LT3060342T (enExample) |
| NO (1) | NO342032B1 (enExample) |
| PL (1) | PL3060342T3 (enExample) |
| PT (1) | PT3060342T (enExample) |
| WO (1) | WO2015059264A1 (enExample) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP3106715B2 (ja) | 1992-07-17 | 2000-11-06 | ブラザー工業株式会社 | ドット印字装置 |
| GB201603819D0 (en) * | 2016-03-04 | 2016-04-20 | Oslofjord Ressurspark As | Device and method for refining particles |
| CN106345547B (zh) * | 2016-11-08 | 2018-09-25 | 锐意微流控医疗科技(常州)有限公司 | 一种微流控芯片 |
| CN106513069A (zh) * | 2016-11-08 | 2017-03-22 | 常州锐德医疗科技有限公司 | 微流控芯片 |
| BR112021007595A2 (pt) * | 2018-10-23 | 2021-07-27 | Trilobite Innovation As | dispositivo de refino de fluido |
| US20220008924A1 (en) * | 2018-11-13 | 2022-01-13 | National Research Council Of Canada | World-to-chip automated interface for centrifugal microfluidic platforms |
| WO2020139210A1 (en) * | 2018-12-28 | 2020-07-02 | Mikro Biyosistemler Elektronik Sanayi Ve Ticaret A.S. | A method of microfluidic particle separation enhancement and the device thereof |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2576805B1 (fr) * | 1985-02-01 | 1989-08-25 | Lyonnaise Eaux | Appareil de filtration tangentielle |
| DE3546091A1 (de) * | 1985-12-24 | 1987-07-02 | Kernforschungsz Karlsruhe | Querstrom-mikrofilter |
| US5788425A (en) * | 1992-07-15 | 1998-08-04 | Imation Corp. | Flexible system for handling articles |
| JP2004042012A (ja) * | 2001-10-26 | 2004-02-12 | Nec Corp | 分離装置、分析システム、分離方法および分離装置の製造方法 |
| US7226540B2 (en) | 2004-02-24 | 2007-06-05 | Becton, Dickinson And Company | MEMS filter module |
| CA2586400A1 (en) * | 2004-11-11 | 2006-05-18 | Agency For Science, Technology And Research | Cell culture device |
| CN100359368C (zh) * | 2004-12-29 | 2008-01-02 | 财团法人工业技术研究院 | 微元件及其制造方法 |
| CN1631549A (zh) * | 2005-01-13 | 2005-06-29 | 浙江大学 | 雾化喷头 |
| US20060266692A1 (en) * | 2005-05-25 | 2006-11-30 | Innovative Micro Technology | Microfabricated cross flow filter and method of manufacture |
| CN101271070B (zh) * | 2008-05-09 | 2010-04-14 | 东北大学 | 微流控毛细管电泳液芯波导荧光检测装置 |
| GB0913523D0 (en) * | 2009-08-03 | 2009-09-16 | Vestfold University College | Improved cross flow and counter flow fluid processing devices |
| RU2539989C2 (ru) * | 2009-12-23 | 2015-01-27 | Сайтовера, Инк. | Система и способ фильтрации частиц |
| US20130299408A1 (en) * | 2010-10-07 | 2013-11-14 | Amiad Water Systems Ltd. | Filtration unit and system |
| CN102840788A (zh) * | 2012-09-19 | 2012-12-26 | 常州大学 | 一种气体板式换热器进、出封头 |
| KR101768445B1 (ko) * | 2017-04-03 | 2017-08-16 | 주식회사 그레넥스 | 섬유상 여과기의 여재 장착 디스크 |
-
2013
- 2013-10-25 NO NO20131411A patent/NO342032B1/no unknown
-
2014
- 2014-10-24 DK DK14789265.7T patent/DK3060342T3/da active
- 2014-10-24 WO PCT/EP2014/072823 patent/WO2015059264A1/en not_active Ceased
- 2014-10-24 LT LTEPPCT/EP2014/072823T patent/LT3060342T/lt unknown
- 2014-10-24 BR BR112016009218-0A patent/BR112016009218B1/pt not_active IP Right Cessation
- 2014-10-24 ES ES14789265T patent/ES2918374T3/es active Active
- 2014-10-24 JP JP2016549634A patent/JP6412146B2/ja not_active Expired - Fee Related
- 2014-10-24 CN CN201480058461.2A patent/CN105848782B/zh active Active
- 2014-10-24 EP EP14789265.7A patent/EP3060342B1/en active Active
- 2014-10-24 PT PT147892657T patent/PT3060342T/pt unknown
- 2014-10-24 US US15/031,288 patent/US10926259B2/en active Active
- 2014-10-24 CA CA2928610A patent/CA2928610C/en active Active
- 2014-10-24 PL PL14789265.7T patent/PL3060342T3/pl unknown
- 2014-10-24 HU HUE14789265A patent/HUE059469T2/hu unknown
Also Published As
| Publication number | Publication date |
|---|---|
| BR112016009218A2 (enExample) | 2017-09-19 |
| EP3060342B1 (en) | 2022-03-16 |
| CA2928610A1 (en) | 2015-04-30 |
| PL3060342T3 (pl) | 2022-07-18 |
| NO342032B1 (no) | 2018-03-12 |
| WO2015059264A1 (en) | 2015-04-30 |
| US10926259B2 (en) | 2021-02-23 |
| CN105848782B (zh) | 2019-08-30 |
| JP2016537198A (ja) | 2016-12-01 |
| HUE059469T2 (hu) | 2022-11-28 |
| CA2928610C (en) | 2022-08-23 |
| NO20131411A1 (no) | 2015-04-27 |
| BR112016009218B1 (pt) | 2022-05-17 |
| LT3060342T (lt) | 2022-07-11 |
| DK3060342T3 (da) | 2022-06-20 |
| EP3060342A1 (en) | 2016-08-31 |
| CN105848782A (zh) | 2016-08-10 |
| US20160279636A1 (en) | 2016-09-29 |
| PT3060342T (pt) | 2022-06-21 |
| JP6412146B2 (ja) | 2018-10-24 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ES2918374T3 (es) | Dispositivo de filtración de fluidos y ensamblaje | |
| US8276760B2 (en) | Serpentine structures for continuous flow particle separations | |
| Sajeesh et al. | Particle separation and sorting in microfluidic devices: a review | |
| US9662602B2 (en) | Method of sorting particles or particle clusters in a fluid flowing in a channel | |
| US20080128331A1 (en) | Particle separation and concentration system | |
| ES2784933T3 (es) | Dispositivo microfluídico | |
| US20200238217A1 (en) | Peristaltic Pump Microfluidic Separator | |
| KR20160064768A (ko) | 나선형 분지채널을 이용한 미세유체칩 여과 장치 및 방법 | |
| Dong et al. | Integratable non-clogging microconcentrator based on counter-flow principle for continuous enrichment of CaSki cells sample | |
| Zhang et al. | Inertial microfluidics: mechanisms and applications | |
| GB2472506A (en) | A Counter-flow filtrating unit and fluid processing device | |
| ES2257574T3 (es) | Metodo y modulo de separacion para la separacion de particulas de una dispersion, en particular de globulos sanguineos de la sangre. | |
| Bayareh et al. | Cancer cell separation using passive mechanisms: A review | |
| JP2007021465A (ja) | 粒子を連続的に濃縮・分離するための流路構造および方法 | |
| KR20130000968A (ko) | 수력학 필터 유닛, 이를 포함하는 수력학 필터 및 이들을 사용하여 표적 물질을 필터링하는 방법 | |
| US20210387191A1 (en) | Fluid refining device | |
| Wewala et al. | Design and simulation of ascending curvilinear micro channel for cancer cell separation from blood | |
| WO2015071515A1 (es) | Dispositivo microfluídico para la separación de líquido del mismo líquido conteniendo partículas deformables sin fuentes de energía externas | |
| JP6923181B2 (ja) | 微粒子分離デバイスおよび微粒子の分離方法 | |
| JP7729536B2 (ja) | 白血球捕捉デバイス | |
| Zheng et al. | Streamline based design of a MEMS device for continuous blood cell separation | |
| CN113117767A (zh) | 一种用于微流体的气泡消溶单元 | |
| Kim et al. | A power-free blood plasma extraction device based on planar crossflow filter microstructure | |
| Indhu et al. | Design of PDMS membrane for CTC separation | |
| Indhu et al. | Design of a bio-filter for particle separation |