Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Merck and Co Inc
Original Assignee
Merck and Co Inc
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Filing date
Publication date
Application filed by Merck and Co IncfiledCriticalMerck and Co Inc
Priority to ES281479ApriorityCriticalpatent/ES281479A1/en
Publication of ES281479A1publicationCriticalpatent/ES281479A1/en
Process for obtaining steroid compounds, especially of 21-glucuronides of 11,17-bis-oxygen-20-ketopregnane unsaturated in ring A, and their salts, of general formula ** (See formula) ** where Z-CH2 is a radical of 11,17-bis-oxygen-20-keto-21-hydroxysteroid unsaturated in ring A, of the pregnane series, in which one of the hydrogens in C-21 has been replaced by the glucuronide fraction, and M is hydrogen or a cation; characterized by the reaction of a 11,17-bis-oxygen-20-keto-21-hydroxysteroid unsaturated in ring A with an alkyl- (tri-O-acyl- β -D-glucopyranosyl bromide) uronate to form the corresponding alkyl- (tri-O-acyl- β -D-glucopyranoside steroid-21-yl) uronate, which is then treated with an alkaline hydrolyzate to form a salt of the steroid 21-glucuronide; and, if you like, by the conversion of the salt into the free acid of the steroid 21-glucuronide. (Machine-translation by Google Translate, not legally binding)
ES281479A1962-10-021962-10-02Procedure for obtaining steroid compounds (Machine-translation by Google Translate, not legally binding)
ExpiredES281479A1
(en)
Procedure for the preparation of a composition to reprimate the development of microorganisms. (Machine-translation by Google Translate, not legally binding)