ES2720883T3 - Sample preparation workstation - Google Patents

Sample preparation workstation Download PDF

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Publication number
ES2720883T3
ES2720883T3 ES13181183T ES13181183T ES2720883T3 ES 2720883 T3 ES2720883 T3 ES 2720883T3 ES 13181183 T ES13181183 T ES 13181183T ES 13181183 T ES13181183 T ES 13181183T ES 2720883 T3 ES2720883 T3 ES 2720883T3
Authority
ES
Spain
Prior art keywords
container
liquid
sample processing
sample
processing container
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
ES13181183T
Other languages
Spanish (es)
Inventor
Lars Andersson
Lee Williams
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Biotage AB
Original Assignee
Biotage AB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biotage AB filed Critical Biotage AB
Application granted granted Critical
Publication of ES2720883T3 publication Critical patent/ES2720883T3/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/0099—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor comprising robots or similar manipulators
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L9/00—Supporting devices; Holding devices
    • B01L9/52—Supports specially adapted for flat sample carriers, e.g. for plates, slides, chips
    • B01L9/523—Supports specially adapted for flat sample carriers, e.g. for plates, slides, chips for multisample carriers, e.g. used for microtitration plates
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/02—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
    • G01N35/04—Details of the conveyor system
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/0409—Moving fluids with specific forces or mechanical means specific forces centrifugal forces
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5025—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures for parallel transport of multiple samples
    • B01L3/50255—Multi-well filtration
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/508—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above
    • B01L3/5085—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above for multiple samples, e.g. microtitration plates
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/40—Concentrating samples
    • G01N1/4055—Concentrating samples by solubility techniques
    • G01N2001/4061—Solvent extraction
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/02—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
    • G01N35/04—Details of the conveyor system
    • G01N2035/0401—Sample carriers, cuvettes or reaction vessels
    • G01N2035/0418—Plate elements with several rows of samples
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/02—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
    • G01N35/04—Details of the conveyor system
    • G01N2035/046—General conveyor features
    • G01N2035/0467—Switching points ("aiguillages")

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Robotics (AREA)
  • Hematology (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)

Abstract

Un instrumento para el procesamiento de muestras que comprende - al menos un recipiente de muestra (102) para contener al menos una muestra líquida; - al menos un recipiente de solvente (110) para contener al menos un solvente; - al menos un recipiente de procesamiento de muestras (100) que comprende un material de procesamiento de muestras, en el que dicho recipiente de procesamiento de muestras tiene un extremo superior con una abertura de entrada de líquido y un extremo inferior con una abertura de salida de líquido; y - un robot de manipulación de líquidos (114) dispuesto para mover una alícuota de dicha muestra líquida desde dicho recipiente de muestra a dicho recipiente de procesamiento de muestras, y para mover una alícuota de dicho solvente desde dicho recipiente de solvente hasta dicho recipiente de procesamiento de muestras; - una mesa móvil (200) dispuesta debajo del contenedor de procesamiento de muestras, teniendo dicha mesa posiciones para varios contenedores de recolección de líquidos (206), por lo que el movimiento de dicha mesa coloca a su vez dichos contenedores de recolección de líquidos (206) directamente debajo de dichos contenedores de procesamiento de muestras (100); - medios para aplicar una presión de gas positiva (116) al extremo superior de dicho recipiente de procesamiento de muestras para empujar los contenidos líquidos de dicho recipiente de procesamiento de muestras a través de la abertura de salida del líquido; en un contenedor de recolección de líquidos caracterizado porque comprende además - un elevador (300) dispuesto para levantar un contenedor de recolección de líquido en posición debajo del contenedor de procesamiento de muestras hasta el nivel de la abertura de salida de líquido de dicho contenedor de procesamiento de muestras; y un contenedor de recolección de desechos (300) directamente debajo del contenedor de procesamiento de muestras, en el que dicho contenedor de recolección de desechos (300) se puede mover verticalmente desde una posición debajo de la mesa móvil (200) a una posición sobre la mesa móvil.A sample processing instrument comprising - at least one sample container (102) for containing at least one liquid sample; - at least one solvent container (110) for containing at least one solvent; - at least one sample processing container (100) comprising a sample processing material, wherein said sample processing container has an upper end with a liquid inlet opening and a lower end with an outlet opening of liquid; and - a liquid handling robot (114) arranged to move an aliquot of said liquid sample from said sample container to said sample processing container, and to move an aliquot of said solvent from said solvent container to said sample container. sample processing; - a mobile table (200) arranged below the sample processing container, said table having positions for several liquid collection containers (206), whereby the movement of said table in turn places said liquid collection containers ( 206) directly below said sample processing containers (100); - means for applying a positive gas pressure (116) to the upper end of said sample processing container to push the liquid contents of said sample processing container through the liquid outlet opening; in a liquid collection container characterized in that it further comprises - a lift (300) arranged to lift a liquid collection container in position below the sample processing container to the level of the liquid outlet opening of said processing container of samples; and a waste collection container (300) directly below the sample processing container, wherein said waste collection container (300) is vertically movable from a position below the movable table (200) to a position above the movable table.

ES13181183T 2013-08-21 2013-08-21 Sample preparation workstation Active ES2720883T3 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP13181183.8A EP2840398B1 (en) 2013-08-21 2013-08-21 Sample preparation workstation

Publications (1)

Publication Number Publication Date
ES2720883T3 true ES2720883T3 (en) 2019-07-25

Family

ID=49000389

Family Applications (1)

Application Number Title Priority Date Filing Date
ES13181183T Active ES2720883T3 (en) 2013-08-21 2013-08-21 Sample preparation workstation

Country Status (10)

Country Link
US (1) US9897621B2 (en)
EP (1) EP2840398B1 (en)
JP (1) JP6499176B2 (en)
KR (1) KR102249195B1 (en)
CN (1) CN105659096B (en)
AU (1) AU2014310668B2 (en)
CA (1) CA2921631C (en)
ES (1) ES2720883T3 (en)
NZ (1) NZ717104A (en)
WO (1) WO2015024921A1 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104764851B (en) * 2015-05-11 2016-02-24 中国烟草总公司郑州烟草研究院 The assay method of 16 kinds of palycyclic aromatics in a kind of tobacco juice for electronic smoke
JP6116075B1 (en) 2015-11-20 2017-04-19 日本航空電子工業株式会社 Electrochemical measurement method, electrochemical measurement apparatus and transducer
CN107621500A (en) * 2016-07-14 2018-01-23 上海可力梅塔生物医药科技有限公司 Amino acid and carnitine tandem mass spectrum derivatization detection method
USD921218S1 (en) 2019-03-29 2021-06-01 Gen-Probe Incorporated Pipette tip holder chain link

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6019314B2 (en) * 1976-06-28 1985-05-15 森下製薬株式会社 2,3,6,7↓-tetrahydro↓-3↓-oxo↓-5H↓-pyridazino[3,4↓-b][1,4]oxazine derivative
FR2572180B1 (en) 1984-10-24 1987-03-20 Eric Marteau D Autry METHOD AND APPARATUS FOR REPAIRING SAMPLES FOR ANALYSIS
JPH04506750A (en) * 1989-07-18 1992-11-26 オンコジーン・サイエンス・インコーポレイテッド automated laboratory equipment
US6133045A (en) * 1998-02-27 2000-10-17 Hamilton Company Automated sample treatment system: apparatus and method
CH693689A5 (en) * 2002-05-31 2003-12-15 Tecan Trading Ag Apparatus to transfer fluids from solid phase extraction plates, for solid phase extraction/elution of organic/inorganic matter, has a controlled transfer unit with the sample carrier for transfer to micro-plates
JP4762240B2 (en) * 2004-07-27 2011-08-31 プロテダイン・コーポレーション Method and apparatus for moving the contents in the wells of a multiwell plate
JP5242532B2 (en) * 2009-10-16 2013-07-24 株式会社日立ハイテクノロジーズ Inspection device
JP6019314B2 (en) * 2012-04-18 2016-11-02 株式会社高尾 Game machine

Also Published As

Publication number Publication date
WO2015024921A1 (en) 2015-02-26
KR102249195B1 (en) 2021-05-06
JP6499176B2 (en) 2019-04-10
EP2840398B1 (en) 2019-01-23
NZ717104A (en) 2019-06-28
CN105659096A (en) 2016-06-08
CA2921631A1 (en) 2015-02-26
AU2014310668B2 (en) 2018-11-08
AU2014310668A1 (en) 2016-03-10
JP2016528512A (en) 2016-09-15
US9897621B2 (en) 2018-02-20
US20160202277A1 (en) 2016-07-14
EP2840398A1 (en) 2015-02-25
CN105659096B (en) 2018-06-15
KR20160048825A (en) 2016-05-04
CA2921631C (en) 2022-07-12

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