ES269996A1 - Procedure for the preparation of new antidiabetic benzolsulfonilureas (Machine-translation by Google Translate, not legally binding)
- Google Patents
Procedure for the preparation of new antidiabetic benzolsulfonilureas (Machine-translation by Google Translate, not legally binding)
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Roche Diagnostics GmbH
CF Boehringer und Soehne GmbH
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Boehringer Mannheim GmbH
CF Boehringer und Soehne GmbH
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Application filed by Boehringer Mannheim GmbH, CF Boehringer und Soehne GmbHfiledCriticalBoehringer Mannheim GmbH
Publication of ES269996A1publicationCriticalpatent/ES269996A1/en
Pharmaceuticals Containing Other Organic And Inorganic Compounds
(AREA)
Abstract
Process for the preparation of new antidiabetic benzolsulfonylureas of the general formula ** (See formula) ** wherein R 1 signifies hydrogen, halogen, lower alkyl or alkoxy groups, and (see formula) represents a cycloalkyl radical, characterized in that according to methods known per se, or a) Benzolsulfonyl combinations of the formula are condensed ** (See formula) ** or combinations of cycloalkyl of the formula ** (See formula) ** wherein R1 has the same meaning as before, W represents an alkoxy group, or a group transferable to the alkoxy group, and one of both residues X and Y means an amino group, while the other is an isocyanate group or a moiety which the reaction conditions is transformed into an isocyanate group, O well, b) Appropriately substituted thioureas, guanidines or isocarbamic benzolsulfonyl ether of the formula are transferred by appropriate hydrolytic measurements ** (See formula) ** O well ** (See formula) ** to the benzolsulfonylureas, after which it is eventually transferred to W, as usual, to the alkoxy group. (Machine-translation by Google Translate, not legally binding)
ES0269996A1960-08-201961-08-18Procedure for the preparation of new antidiabetic benzolsulfonilureas (Machine-translation by Google Translate, not legally binding)
ExpiredES269996A1
(en)
Procedure for the aminoalcohilation of aromatic or aromatic-heterocyclic secondary amino (Machine-translation by Google Translate, not legally binding)