ES2683171T3 - Aparato y método para determinar unos parámetros de inyección de un medio de contraste para controlar la intensidad de la señal durante angiografía por resonancia magnética - Google Patents
Aparato y método para determinar unos parámetros de inyección de un medio de contraste para controlar la intensidad de la señal durante angiografía por resonancia magnética Download PDFInfo
- Publication number
- ES2683171T3 ES2683171T3 ES12712474.1T ES12712474T ES2683171T3 ES 2683171 T3 ES2683171 T3 ES 2683171T3 ES 12712474 T ES12712474 T ES 12712474T ES 2683171 T3 ES2683171 T3 ES 2683171T3
- Authority
- ES
- Spain
- Prior art keywords
- contrast agent
- concentration
- injection
- rate
- syringe
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- 238000002347 injection Methods 0.000 title claims abstract description 325
- 239000007924 injection Substances 0.000 title claims abstract description 325
- 239000002872 contrast media Substances 0.000 title claims abstract description 304
- 238000000034 method Methods 0.000 title claims abstract description 73
- 238000002583 angiography Methods 0.000 title claims description 5
- 230000017531 blood circulation Effects 0.000 claims abstract description 68
- 230000000747 cardiac effect Effects 0.000 claims abstract description 32
- 239000008280 blood Substances 0.000 claims abstract description 4
- 210000004369 blood Anatomy 0.000 claims abstract description 4
- 239000003085 diluting agent Substances 0.000 claims description 70
- 239000003795 chemical substances by application Substances 0.000 claims description 7
- 239000012895 dilution Substances 0.000 claims description 5
- 238000010790 dilution Methods 0.000 claims description 5
- 239000012530 fluid Substances 0.000 description 54
- 230000033001 locomotion Effects 0.000 description 18
- 238000004891 communication Methods 0.000 description 9
- 238000003384 imaging method Methods 0.000 description 7
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 6
- 238000004364 calculation method Methods 0.000 description 6
- 229940039231 contrast media Drugs 0.000 description 5
- LGMLJQFQKXPRGA-VPVMAENOSA-K gadopentetate dimeglumine Chemical compound [Gd+3].CNC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO.CNC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO.OC(=O)CN(CC([O-])=O)CCN(CC([O-])=O)CCN(CC(O)=O)CC([O-])=O LGMLJQFQKXPRGA-VPVMAENOSA-K 0.000 description 5
- 238000002595 magnetic resonance imaging Methods 0.000 description 5
- 230000001225 therapeutic effect Effects 0.000 description 5
- 210000005166 vasculature Anatomy 0.000 description 5
- 238000002591 computed tomography Methods 0.000 description 4
- 210000003462 vein Anatomy 0.000 description 4
- 238000013170 computed tomography imaging Methods 0.000 description 3
- 230000008878 coupling Effects 0.000 description 3
- 238000010168 coupling process Methods 0.000 description 3
- 238000005859 coupling reaction Methods 0.000 description 3
- 230000007423 decrease Effects 0.000 description 3
- 238000007599 discharging Methods 0.000 description 3
- 230000006870 function Effects 0.000 description 3
- 101100077717 Mus musculus Morn2 gene Proteins 0.000 description 2
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- 230000002457 bidirectional effect Effects 0.000 description 2
- 238000002512 chemotherapy Methods 0.000 description 2
- 238000002059 diagnostic imaging Methods 0.000 description 2
- 238000010586 diagram Methods 0.000 description 2
- 239000003814 drug Substances 0.000 description 2
- 238000009434 installation Methods 0.000 description 2
- 238000012986 modification Methods 0.000 description 2
- 230000004048 modification Effects 0.000 description 2
- 230000003287 optical effect Effects 0.000 description 2
- 238000005457 optimization Methods 0.000 description 2
- 238000002600 positron emission tomography Methods 0.000 description 2
- 239000012217 radiopharmaceutical Substances 0.000 description 2
- 229940121896 radiopharmaceutical Drugs 0.000 description 2
- 230000002799 radiopharmaceutical effect Effects 0.000 description 2
- 238000011084 recovery Methods 0.000 description 2
- 238000012216 screening Methods 0.000 description 2
- 239000000126 substance Substances 0.000 description 2
- 238000012360 testing method Methods 0.000 description 2
- 206010002329 Aneurysm Diseases 0.000 description 1
- 241000246358 Thymus Species 0.000 description 1
- 235000007303 Thymus vulgaris Nutrition 0.000 description 1
- 101150047086 arm gene Proteins 0.000 description 1
- 210000001367 artery Anatomy 0.000 description 1
- 230000005540 biological transmission Effects 0.000 description 1
- 230000036772 blood pressure Effects 0.000 description 1
- 210000004204 blood vessel Anatomy 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 239000004020 conductor Substances 0.000 description 1
- 238000013479 data entry Methods 0.000 description 1
- 238000013500 data storage Methods 0.000 description 1
- 230000001419 dependent effect Effects 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 238000009472 formulation Methods 0.000 description 1
- 239000000446 fuel Substances 0.000 description 1
- PIZALBORPSCYJU-QSQMUHTISA-H gadofosveset Chemical compound O.[Na+].[Na+].[Na+].[Gd+3].C1CC(OP([O-])(=O)OC[C@@H](CN(CCN(CC([O-])=O)CC([O-])=O)CC(=O)[O-])N(CC([O-])=O)CC([O-])=O)CCC1(C=1C=CC=CC=1)C1=CC=CC=C1 PIZALBORPSCYJU-QSQMUHTISA-H 0.000 description 1
- 230000010354 integration Effects 0.000 description 1
- 238000010253 intravenous injection Methods 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 238000013178 mathematical model Methods 0.000 description 1
- 238000010339 medical test Methods 0.000 description 1
- 238000002156 mixing Methods 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 229940028444 muse Drugs 0.000 description 1
- 238000001208 nuclear magnetic resonance pulse sequence Methods 0.000 description 1
- 230000035699 permeability Effects 0.000 description 1
- 229940071643 prefilled syringe Drugs 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 230000008569 process Effects 0.000 description 1
- GMVPRGQOIOIIMI-DWKJAMRDSA-N prostaglandin E1 Chemical compound CCCCC[C@H](O)\C=C\[C@H]1[C@H](O)CC(=O)[C@@H]1CCCCCCC(O)=O GMVPRGQOIOIIMI-DWKJAMRDSA-N 0.000 description 1
- 238000010926 purge Methods 0.000 description 1
- 230000004044 response Effects 0.000 description 1
- 230000035945 sensitivity Effects 0.000 description 1
- 239000000243 solution Substances 0.000 description 1
- 230000001360 synchronised effect Effects 0.000 description 1
- 239000001585 thymus vulgaris Substances 0.000 description 1
- 238000012546 transfer Methods 0.000 description 1
- 238000002604 ultrasonography Methods 0.000 description 1
- 238000012285 ultrasound imaging Methods 0.000 description 1
- 230000000007 visual effect Effects 0.000 description 1
- 238000012800 visualization Methods 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/05—Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves
- A61B5/055—Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves involving electronic [EMR] or nuclear [NMR] magnetic resonance, e.g. magnetic resonance imaging
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/007—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests for contrast media
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/142—Pressure infusion, e.g. using pumps
- A61M5/145—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons
- A61M5/1452—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons pressurised by means of pistons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/142—Pressure infusion, e.g. using pumps
- A61M5/145—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons
- A61M5/1452—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons pressurised by means of pistons
- A61M5/14546—Front-loading type injectors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/142—Pressure infusion, e.g. using pumps
- A61M5/145—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons
- A61M5/1452—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons pressurised by means of pistons
- A61M5/14546—Front-loading type injectors
- A61M2005/14553—Front-loading type injectors comprising a pressure jacket
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Vascular Medicine (AREA)
- Anesthesiology (AREA)
- Hematology (AREA)
- Physics & Mathematics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- High Energy & Nuclear Physics (AREA)
- Radiology & Medical Imaging (AREA)
- Biophysics (AREA)
- Pathology (AREA)
- Medical Informatics (AREA)
- Molecular Biology (AREA)
- Surgery (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
- Magnetic Resonance Imaging Apparatus (AREA)
- Apparatus For Radiation Diagnosis (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161453975P | 2011-03-18 | 2011-03-18 | |
| US201161453975P | 2011-03-18 | ||
| PCT/US2012/029038 WO2012129022A1 (en) | 2011-03-18 | 2012-03-14 | Apparatus and method to determine contrast media injection parameters to control signal intensity during magnetic resonance angiography |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2683171T3 true ES2683171T3 (es) | 2018-09-25 |
Family
ID=45931021
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES12712474.1T Active ES2683171T3 (es) | 2011-03-18 | 2012-03-14 | Aparato y método para determinar unos parámetros de inyección de un medio de contraste para controlar la intensidad de la señal durante angiografía por resonancia magnética |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US9744289B2 (enExample) |
| EP (1) | EP2686040B1 (enExample) |
| JP (1) | JP6012641B2 (enExample) |
| CN (1) | CN103561800B (enExample) |
| BR (1) | BR112013023845A8 (enExample) |
| ES (1) | ES2683171T3 (enExample) |
| RU (1) | RU2603823C2 (enExample) |
| WO (1) | WO2012129022A1 (enExample) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104869903B (zh) * | 2012-12-19 | 2020-08-28 | 皇家飞利浦有限公司 | X-射线控制的造影剂注射 |
| EP3212256A4 (en) | 2014-10-28 | 2018-07-18 | Bayer HealthCare LLC | Self-orienting pressure jacket and pressure jacket-to-injector interface |
| US9199033B1 (en) | 2014-10-28 | 2015-12-01 | Bayer Healthcare Llc | Self-orienting syringe and syringe interface |
| JP6726179B2 (ja) | 2014-10-28 | 2020-07-22 | バイエル・ヘルスケア・エルエルシーBayer HealthCare LLC | 自己配向圧力ジャケットおよび圧力ジャケット対インジェクタインタフェース |
| NO2689315T3 (enExample) | 2014-10-28 | 2018-04-14 | ||
| WO2016084940A1 (ja) * | 2014-11-28 | 2016-06-02 | 株式会社根本杏林堂 | 薬液注入装置 |
| CN108472433B (zh) | 2015-11-13 | 2021-12-14 | 拜耳医药保健有限公司 | 嵌套式针筒组装件 |
| DE102015222853A1 (de) * | 2015-11-19 | 2017-05-24 | Siemens Healthcare Gmbh | Verfahren zum automatischen Ermitteln eines Kontrastmittel-Injektionsprotokolls |
| DE102016211902A1 (de) * | 2016-06-30 | 2018-01-04 | Siemens Healthcare Gmbh | Verfahren und System zur kontrastmittelbasierten medizinischen Bildgebung |
| CN109395203A (zh) * | 2017-08-18 | 2019-03-01 | 南京感控通化工产品经营部 | 一种高压注射器的方案管理方法 |
| US11191893B2 (en) | 2018-01-31 | 2021-12-07 | Bayer Healthcare Llc | System and method for syringe engagement with injector |
| JP7243973B2 (ja) * | 2018-10-25 | 2023-03-22 | 国立大学法人広島大学 | シミュレータ、該シミュレータを備える注入装置または撮像システム、及びシミュレーションプログラム |
| WO2020162596A1 (ja) * | 2019-02-08 | 2020-08-13 | 株式会社サーキュラス | 薬液注入装置および薬液注入システム |
| CN111790017A (zh) * | 2019-11-27 | 2020-10-20 | 南京感控通化工产品经营部 | 一种用于控制不同注射程序的核磁高压注射系统 |
| KR20220072401A (ko) * | 2020-11-25 | 2022-06-02 | 우승태 | 조영제 주입 장치 및 이의 사용방법 |
| JP2024505235A (ja) * | 2021-01-29 | 2024-02-05 | バイエル・ヘルスケア・エルエルシー | プロトコル変換のためのシステム、方法、およびコンピュータプログラム製品 |
| US11598834B2 (en) * | 2021-07-02 | 2023-03-07 | Canon Medical Systems Corporation | Magnetic resonance imaging apparatus |
| KR102809396B1 (ko) * | 2022-07-21 | 2025-05-23 | 신화주택(주) | 다종 조영제 자동 주입 장치의 동작 제어 방법 및 장치 |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5417213A (en) | 1993-06-07 | 1995-05-23 | Prince; Martin R. | Magnetic resonance arteriography with dynamic intravenous contrast agents |
| DE1258262T1 (de) | 1993-10-28 | 2003-04-10 | Medrad, Inc. | System zur Kontrastmittelabgabe |
| US6397098B1 (en) | 1994-09-21 | 2002-05-28 | Medrad, Inc. | Data communication and control for medical imaging systems |
| US5840026A (en) | 1994-09-21 | 1998-11-24 | Medrad, Inc. | Patient specific dosing contrast delivery systems and methods |
| RU2117493C1 (ru) * | 1996-04-02 | 1998-08-20 | Сысолятин Павел Гаврилович | Способ введения лекарственных средств в полость сустава |
| US6635030B1 (en) | 1999-04-09 | 2003-10-21 | B.H.B. Llc | Contrast injector for injecting a contrast medium to generate prolonged uniform vascular enhancement |
| US6055985A (en) | 1999-04-09 | 2000-05-02 | B.H.B., L.C. | Methods for injecting a contrast medium to generate prolonged uniform vascular enhancement |
| US6928338B1 (en) | 2001-08-10 | 2005-08-09 | Medtronic, Inc. | Decision information system for drug delivery devices |
| JP4731795B2 (ja) * | 2003-02-18 | 2011-07-27 | 株式会社根本杏林堂 | 薬液注入装置 |
| EP1647291A4 (en) * | 2003-07-18 | 2007-06-06 | Nemoto Kyorindo Co Ltd | DEVICE FOR INFUSING MEDICAMENTS FOR DISPLAYING AN IMAGE OF THE INFLUENZED INFUSION CONDITION |
| EP1656067A1 (en) * | 2003-08-12 | 2006-05-17 | Philips Intellectual Property & Standards GmbH | Device and method for producing images of the heart |
| JPWO2007116840A1 (ja) | 2006-04-04 | 2009-08-20 | 株式会社根本杏林堂 | 薬液注入装置 |
| DK2097835T3 (en) | 2006-12-29 | 2018-09-03 | Bayer Healthcare Llc | PATIENT-BASED PARAMETER GENERATION SYSTEMS FOR MEDICAL INJECTION PROCEDURES |
| ES2421327T3 (es) * | 2007-05-04 | 2013-08-30 | Mallinckrodt Llc | Métodos para controlar inyecciones de fluidos médicos |
| JP5437240B2 (ja) * | 2007-07-17 | 2014-03-12 | メドラッド インコーポレーテッド | 心肺機能の評価、及び流体搬送の手順のパラメータを決定する装置、システム及び方法 |
-
2012
- 2012-03-14 EP EP12712474.1A patent/EP2686040B1/en not_active Not-in-force
- 2012-03-14 JP JP2013558136A patent/JP6012641B2/ja not_active Expired - Fee Related
- 2012-03-14 WO PCT/US2012/029038 patent/WO2012129022A1/en not_active Ceased
- 2012-03-14 US US14/003,893 patent/US9744289B2/en not_active Expired - Fee Related
- 2012-03-14 CN CN201280024053.6A patent/CN103561800B/zh not_active Expired - Fee Related
- 2012-03-14 ES ES12712474.1T patent/ES2683171T3/es active Active
- 2012-03-14 RU RU2013140949/14A patent/RU2603823C2/ru not_active IP Right Cessation
- 2012-03-14 BR BR112013023845A patent/BR112013023845A8/pt active Search and Examination
Also Published As
| Publication number | Publication date |
|---|---|
| JP2014509529A (ja) | 2014-04-21 |
| BR112013023845A2 (pt) | 2016-12-13 |
| US20130345548A1 (en) | 2013-12-26 |
| JP6012641B2 (ja) | 2016-10-25 |
| BR112013023845A8 (pt) | 2018-02-06 |
| US9744289B2 (en) | 2017-08-29 |
| RU2603823C2 (ru) | 2016-11-27 |
| EP2686040B1 (en) | 2018-05-09 |
| WO2012129022A1 (en) | 2012-09-27 |
| RU2013140949A (ru) | 2015-04-27 |
| CN103561800A (zh) | 2014-02-05 |
| EP2686040A1 (en) | 2014-01-22 |
| CN103561800B (zh) | 2017-02-15 |
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