ES2672632A1 - Procedure for obtaining an extract for topical epithelizing, healing and regenerative skin compositions (Machine-translation by Google Translate, not legally binding) - Google Patents

Procedure for obtaining an extract for topical epithelizing, healing and regenerative skin compositions (Machine-translation by Google Translate, not legally binding) Download PDF

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Publication number
ES2672632A1
ES2672632A1 ES201601085A ES201601085A ES2672632A1 ES 2672632 A1 ES2672632 A1 ES 2672632A1 ES 201601085 A ES201601085 A ES 201601085A ES 201601085 A ES201601085 A ES 201601085A ES 2672632 A1 ES2672632 A1 ES 2672632A1
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Prior art keywords
extract
obtaining
sambucus nigra
healing
topical
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Granted
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ES201601085A
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Spanish (es)
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ES2672632B1 (en
Inventor
Matilde ROS GIL
Marta USÓ ROS
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MARTA USO ROS
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Matilde ROS GIL
Marta USÓ ROS
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Priority to ES201601085A priority Critical patent/ES2672632B1/en
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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/35Caprifoliaceae (Honeysuckle family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/44Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q17/00Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin

Abstract

Procedure for obtaining extract for topical epithelizing, healing and regenerative skin compositions. The present invention relates to an extract for compositions for topical use obtained from Sambucus nigra, extracted from the woody parts of the branches of the shrub Sambucus nigra, and virgin olive oil, and which has the properties of being epitalising, healing and regenerative of the damaged skin, soothing and anti-inflammatory, in particular in case of burns, fragile skin, ulcerations, chilblains, hemorrhoids, sores, eczema, etc. The invention also relates to the process for obtaining the Sambucus nigra extract. (Machine-translation by Google Translate, not legally binding)

Description

PROCEDIMIENTO DE OBTENCiÓN DE EXTRACTO PARA COMPOSICIONES DE USO TÓPICO EPITELlZANTE, CICATRIZANTE y REGENERATIVAS DE LA PIEL PROCEDURE FOR OBTAINING EXTRACT FOR COMPOSITIONS TYPICAL USE EPITELLZANTE, CICATRIZANTE and REGENERATIVES OF THE SKIN

Campo y antecedentes de la invención Field and background of the invention


La presente invención se refiere a un extracto para composiciones de uso tópico epitelizante, cicatrizante y regenerativas de la piel.

The present invention relates to an extract for epithelizing, healing and regenerative topical skin use compositions.

Más en particular, la presente invención se refiere a un extracto de
Sambucus nigra, extraído a partir de las partes leñosas de las ramas del arbusto Sambucus nigra, aceite de oliva virgen, y que presenta propiedades epitalizantes, cicatrizantes y regenerativas de la piel dañada, calmantes y antiinflamatorias, en particular en caso de quemaduras, píel frágil, ulceraciones, sabañones, hemorroides, llagas, eczemas, etc.
More particularly, the present invention relates to an extract of
Sambucus nigra, extracted from the woody parts of the branches of the Sambucus nigra shrub, virgin olive oil, and which has epitalizing, healing and regenerative properties of damaged, soothing and anti-inflammatory skin, in particular in case of burns, fragile skin , ulcerations, chilblains, hemorrhoids, sores, eczema, etc.

Igualmente, la invención se refiere al procedimiento de obtención del extracto mencionado. Similarly, the invention relates to the process for obtaining the aforementioned extract.

El Sambucus nigra es un arbusto caducifolio de la familia de las Caprifoliáceas de tronco con corteza suberosa y ramas con médula blanquecina muy desarrollada. En la terapia natural y la homeopatía, este arbusto es conocido por sus propiedades medicinales desde antiguo, en especial se emplean sus flores, hojas y frutos, ya que contiene aceites esenciales, taninos, ácidos orgánicos, aminoácidos, azúcares, vitamina C y diversos glucósidos tales como vitamina P (rutina) y sambunigrina. The Sambucus nigra is a deciduous shrub of the family of the Caprifoliáceas of trunk with suberosa bark and branches with whitish marrow very developed. In natural therapy and homeopathy, this shrub is known for its medicinal properties since ancient times, especially its flowers, leaves and fruits are used, as it contains essential oils, tannins, organic acids, amino acids, sugars, vitamin C and various glycosides such as vitamin P (rutin) and sambunigrin.

Así, las cabezas florales se usan en infusión, dando una bebida refrescante, muy usada en el norte de Europa yen los Balcanes. La infusión de flores secas o de sus hojas es un buen remedio para tratar afecciones de las vías respiratorias altas y como anticatarral gracias a su acción sudorífica. La infusión de sus flores también se emplea como calmante en el tratamiento de trastornos nerviosos ligeros tales como insomnios, migrañas, dolores de cabeza e inflamaciones dolorosas, así como infusión depurativa y diurética en caso de afecciones renales. También se usan sus flores en forma de infusión enfriada externamente en compresas y baños para los ojos. Los frutos del Sambucus nigra se emplean para la preparación de mermeladas, zumos y licores y la decocción de su corteza, tallos, hojas, flores, frutos y raíces de emplean para tratar afecciones pulmonares, tos, infecciones respiratorias, etc. Thus, the floral heads are used in infusion, giving a refreshing drink, widely used in northern Europe and in the Balkans. The infusion of dried flowers or their leaves is a good remedy to treat conditions of the upper respiratory tract and as an anti-catarrhal thanks to its sweaty action. The infusion of its flowers is also used as a painkiller in the treatment of mild nervous disorders such as insomnia, migraines, headaches and painful inflammations, as well as depurative and diuretic infusion in case of kidney conditions. Its flowers are also used as an externally cooled infusion in pads and eye baths. The fruits of Sambucus nigra are used for the preparation of jams, juices and spirits and the decoction of their bark, stems, leaves, flowers, fruits and roots used to treat lung conditions, cough, respiratory infections, etc.

En el estado de la técnica anterior se pueden encontrar diversos documentos referidos a la utilización de Sambucus nigra. Por ejemplo, la ES 2148113, "Nueva formulación medicinal a base de extractos nebulizados de plantas, procedimiento para su preparación y aplicaciones", describe una formulación medicinal constituida esencialmente por una mezcla de extractos nebulizados de llantén, eucalipto, tomillo, yemas de pino, equináceas, saúco y propolia que se obtiene por la disolución en agua con agitación continua de los referidos extractos, siendo útil para el tratamiento y la prevención de afecciones del aparato respiratorio. Various documents referring to the use of Sambucus nigra can be found in the prior art. For example, ES 2148113, "New medicinal formulation based on nebulized plant extracts, procedure for its preparation and applications", describes a medicinal formulation consisting essentially of a mixture of nebulized extracts of plantain, eucalyptus, thyme, pine buds, Echinacea, elderberry and propolia obtained by dissolving in water with continuous agitation of the said extracts, being useful for the treatment and prevention of respiratory diseases.

La ES 2134171 , "Composición de plantas para eliminar el dolor de muelas y dientes producido por caries o flemones", se refiere a una composición consistente en una mezcla de extractos de flores y hojas de Sambucus ebulus, Sambucus racemosa, Sambucus nigra en las mismas proporciones que, después de su elaboración, son capaces de eliminar el dolor de muelas y dientes, producido por caries y flemones. ES 2134171, "Composition of plants to eliminate tooth and tooth ache caused by caries or phlegm", refers to a composition consisting of a mixture of flower and leaf extracts of Sambucus ebulus, Sambucus racemosa, Sambucus nigra in them proportions that, after its elaboration, are capable of eliminating toothache and teeth, caused by decay and phlegm.

La ES 2140576 T3, "Composición para la piel que contiene saúco", describe una decocción de Sambucus nigra para la preparación de un medicamento para el tratamiento de lesiones sobre el cuerpo humano o de un animal, caracterizada porque ramas de dos años son sometidas a ebullición en agua desde un tiempo de generalmente 15' a 10 horas, después se refrigera y se recupera la decocción y al uso de dicha decocción para el tratamiento de lesiones de úlcera decúbitos o lesiones provocadas por quemaduras y eritemas solares. ES 2140576 T3, "Composition for elder-containing skin", describes a decoction of Sambucus nigra for the preparation of a medicament for the treatment of lesions on the human body or an animal, characterized in that branches of two years are subjected to boil in water from a time of generally 15 'to 10 hours, then the decoction is cooled and recovered and the use of said decoction for the treatment of pressure ulcer lesions or lesions caused by sunburn and erythema.

Objeto de la invención Object of the invention

El objeto de la presente invención es un extracto con propiedades epitelizantes, cicatrizantes y regenerativo de la piel obtenida del Sambucus nigra, como ingrediente activo principal, extraído a partir de las partes leñosas de las ramas del arbusto Sambucus nigra, así como aceite de oliva virgen. The object of the present invention is an extract with epithelializing, healing and regenerative properties of the skin obtained from Sambucus nigra, as the main active ingredient, extracted from the woody parts of the branches of the Sambucus nigra shrub, as well as virgin olive oil .

Es igualmente objeto de la invención el procedimiento de obtención del extracto citado anteriormente. The method of obtaining the aforementioned extract is also the object of the invention.

Descripción de la Invención Description of the Invention

Según un primer aspecto de la presente invención, se proporciona un extracto con propiedades epitelizantes, cicatrizantes y regenerativa de la piel obtenido del Sambucus nigra, como ingrediente activo principal, extraído a partir de las partes leñosas de las ramas del arbusto Sambucus nigra, así como aceite de oliva virgen. According to a first aspect of the present invention, an extract with epithelializing, healing and regenerative properties of the skin obtained from Sambucus nigra is provided as the main active ingredient, extracted from the woody parts of the branches of the Sambucus nigra bush, as well as virgin olive oil

En el contexto de la presente invención, con el término "aceite de oliva virgen" se pretende indicar un aceite de oliva obtenido exclusivamente por procedimientos mecánicos, ya sea por presión o centrifugación, y sin la intervención de ningún proceso químico. In the context of the present invention, the term "virgin olive oil" is intended to indicate an olive oil obtained exclusively by mechanical procedures, either by pressure or centrifugation, and without the intervention of any chemical process.

El extracto se obtiene a partir de las partes leñosas de las ramas del arbusto Sambucus nigra, las cuales, debidamente limpias y troceadas, se someten a un proceso de extracción con aceite de oliva virgen , a una temperatura de 70ce -100ce durante un periodo de tiempo de 2 a 3 horas. A continuación, se lleva a cabo un proceso de clarificación de los restos leñosos desprendidos durante la extracción y finalmente el extracto resultante se separa de los residuos mediante un tamizado fino. Este proceso de clarificación tiene como objeto retirar los posibles residuos o materiales no deseados presentes en el extracto, bien sea mediante decantación o sedimentación o bien por centrifugación o filtración, por ejemplo en un filtro prensa. The extract is obtained from the woody parts of the branches of the Sambucus nigra bush, which, properly cleaned and chopped, are subjected to an extraction process with virgin olive oil, at a temperature of 70ce -100ce during a period of Time of 2 to 3 hours. Next, a process of clarification of the woody debris detached during the extraction is carried out and finally the resulting extract is separated from the residues by fine sieving. The purpose of this clarification process is to remove any unwanted residues or materials present in the extract, either by decantation or sedimentation or by centrifugation or filtration, for example in a filter press.

El extracto obtenido se somete a un tratamiento térmico a una temperatura en el rango de 700e -BOoe , manteniendo el régimen de The extract obtained is subjected to a heat treatment at a temperature in the range of 700e-BOoe, maintaining the regimen of

temperatura de forma que se minimicen las posibles pérdidas de componentes termolábiles presentes en el extracto y posteriormente añadiendo aceite de oliva virgen hasta recuperar el volumen perdido durante el proceso. temperature so that the possible losses of thermolabile components present in the extract are minimized and subsequently adding virgin olive oil until the volume lost during the process is recovered.

Claims (2)

REIVINDICACIONES
1. one.
PROCEDIMIENTO DE OBTENCiÓN DE EXTRACTO PARA PROCESS FROM Obtaining FROM ABSTRACT FOR
s s
COMPOSICIONES DE USO TÓPICO EPITELlZANTE, CICATRIZANTE Y REGENERATIVAS DE LA PIEL obtenido del Sambucus nigra como ingrediente activo principal, extraído a partir de las partes leñosas de las ramas del arbusto Sambucus nigra, así como aceite de oliva virgen. COMPOSITIONS FOR TOPICAL USE EPITELlZANTE, CICATRIZANTE AND REGENERATIVES OF THE SKIN obtained from the Sambucus nigra as the main active ingredient, extracted from the woody parts of the branches of the Sambucus nigra bush, as well as virgin olive oil.
2. 2.
PROCEDIMIENTO DE OBTENCiÓN DE EXTRACTO PARA PROCESS FROM Obtaining FROM ABSTRACT FOR
10 10
COMPOSICIONES DE USO TÓPICO EPITELlZANTE, CICATRIZANTE Y REGENERATIVAS DE LA PIEL, según reivindicación 1, caracterizado por las siguientes etapas:    COMPOSITIONS OF TOPIC USE EPITELLZANTE, CICATRIZANTE AND REGENERATIVES OF THE SKIN, according to claim 1, characterized by the following steps:
lS lS
i) Extracción del extracto de Sambucus nigra a partir de las partes leñosas de las ramas del arbusto Sambucus nigra, las cuales, debidamente limpias y troceadas, se someten a un proceso de extracción con aceite de oliva virgen, a una temperatura de 70°C 100°C durante un periodo de tiempo de 2 a 3 horas, seguida de una proceso de clarificación . i) Extraction of the Sambucus nigra extract from the woody parts of the branches of the Sambucus nigra shrub, which, properly cleaned and chopped, undergo an extraction process with virgin olive oil, at a temperature of 70 ° C 100 ° C for a period of 2 to 3 hours, followed by a clarification process.
20 twenty
ii) Concentración del extracto obtenido en i) mediante tratamiento térmico a una temperatura en el rango de 70°C -80°C Y adición de aceite de oliva virgen hasta recuperar el volumen perdido durante el rocesoproce. so. p      ii) Concentration of the extract obtained in i) by heat treatment at a temperature in the range of 70 ° C -80 ° C and addition of virgin olive oil until the volume lost during rocesoproce is recovered. SW. p      
ES201601085A 2016-12-15 2016-12-15 Procedure for obtaining an extract for topical epithelizing, healing and regenerative skin compositions Active ES2672632B1 (en)

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Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES434338A1 (en) * 1975-01-31 1976-12-01 Quintanilla Hermoso Procedure for preparing a compound against burns. (Machine-translation by Google Translate, not legally binding)
ES2020654A6 (en) * 1990-07-19 1991-08-16 Vega Salinas Luis De Procedure for manufacture of curative ointments
ES2024333A6 (en) * 1990-11-02 1992-02-16 Zabala Villapun Gumersindo Procedure for obtaining a natural ointment
ES2052443A1 (en) * 1992-11-06 1994-07-01 Garcia Manuel Vidueira Antiseptic cream for skin burns
ES2056029A1 (en) * 1993-03-02 1994-09-16 Vitores Raquel Maria Iglesias Composition of a product for skin regeneration
ES2095192A1 (en) * 1995-05-23 1997-02-01 Gomez Isabel Ezquerra Burn ointment
ES2176114A1 (en) * 2001-03-27 2002-11-16 Vila Falco M Dolors Hydrating cream for burns
EP2586450A1 (en) * 2010-03-17 2013-05-01 Ricardo Lombardero Calzon Cream for burns

Patent Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES434338A1 (en) * 1975-01-31 1976-12-01 Quintanilla Hermoso Procedure for preparing a compound against burns. (Machine-translation by Google Translate, not legally binding)
ES2020654A6 (en) * 1990-07-19 1991-08-16 Vega Salinas Luis De Procedure for manufacture of curative ointments
ES2024333A6 (en) * 1990-11-02 1992-02-16 Zabala Villapun Gumersindo Procedure for obtaining a natural ointment
ES2052443A1 (en) * 1992-11-06 1994-07-01 Garcia Manuel Vidueira Antiseptic cream for skin burns
ES2056029A1 (en) * 1993-03-02 1994-09-16 Vitores Raquel Maria Iglesias Composition of a product for skin regeneration
ES2095192A1 (en) * 1995-05-23 1997-02-01 Gomez Isabel Ezquerra Burn ointment
ES2176114A1 (en) * 2001-03-27 2002-11-16 Vila Falco M Dolors Hydrating cream for burns
EP2586450A1 (en) * 2010-03-17 2013-05-01 Ricardo Lombardero Calzon Cream for burns

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Publication number Publication date
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