ES2610241T3 - Composiciones y usos para el tratamiento de lesiones miocárdicas progresivas debidas a una insuficiencia vascular - Google Patents

Composiciones y usos para el tratamiento de lesiones miocárdicas progresivas debidas a una insuficiencia vascular Download PDF

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Publication number
ES2610241T3
ES2610241T3 ES10825743.7T ES10825743T ES2610241T3 ES 2610241 T3 ES2610241 T3 ES 2610241T3 ES 10825743 T ES10825743 T ES 10825743T ES 2610241 T3 ES2610241 T3 ES 2610241T3
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Spain
Prior art keywords
cells
months
cxcr
years
composition
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Active
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ES10825743.7T
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English (en)
Spanish (es)
Inventor
Andrew L. Pecora
Robert A. Preti
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Amorcyte LLC
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Amorcyte LLC
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Publication of ES2610241T3 publication Critical patent/ES2610241T3/es
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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14Blood; Artificial blood
    • A61K35/15Cells of the myeloid line, e.g. granulocytes, basophils, eosinophils, neutrophils, leucocytes, monocytes, macrophages or mast cells; Myeloid precursor cells; Antigen-presenting cells, e.g. dendritic cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/28Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18Growth factors; Growth regulators
    • A61K38/1883Neuregulins, e.g.. p185erbB2 ligands, glial growth factor, heregulin, ARIA, neu differentiation factor
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/04Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/06Antiarrhythmics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0634Cells from the blood or the immune system
    • C12N5/0647Haematopoietic stem cells; Uncommitted or multipotent progenitors

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Hematology (AREA)
  • Zoology (AREA)
  • Immunology (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cardiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Epidemiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Virology (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Hospice & Palliative Care (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
ES10825743.7T 2009-10-23 2010-10-22 Composiciones y usos para el tratamiento de lesiones miocárdicas progresivas debidas a una insuficiencia vascular Active ES2610241T3 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US25453909P 2009-10-23 2009-10-23
US254539P 2009-10-23
PCT/US2010/053744 WO2011050266A1 (en) 2009-10-23 2010-10-22 Compositions and methods for treating progressive myocardial injury due to a vascular insufficiency

Publications (1)

Publication Number Publication Date
ES2610241T3 true ES2610241T3 (es) 2017-04-26

Family

ID=43900703

Family Applications (2)

Application Number Title Priority Date Filing Date
ES10825743.7T Active ES2610241T3 (es) 2009-10-23 2010-10-22 Composiciones y usos para el tratamiento de lesiones miocárdicas progresivas debidas a una insuficiencia vascular
ES16198257T Active ES2845691T3 (es) 2009-10-23 2010-10-22 Composiciones y usos para el tratamiento de lesiones miocárdicas progresivas debidas a una insuficiencia vascular

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES16198257T Active ES2845691T3 (es) 2009-10-23 2010-10-22 Composiciones y usos para el tratamiento de lesiones miocárdicas progresivas debidas a una insuficiencia vascular

Country Status (6)

Country Link
EP (2) EP3170891B1 (cg-RX-API-DMAC7.html)
JP (5) JP5709880B2 (cg-RX-API-DMAC7.html)
CA (1) CA2778664C (cg-RX-API-DMAC7.html)
ES (2) ES2610241T3 (cg-RX-API-DMAC7.html)
GB (1) GB2487339A (cg-RX-API-DMAC7.html)
WO (1) WO2011050266A1 (cg-RX-API-DMAC7.html)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20110076255A1 (en) 2005-11-07 2011-03-31 Pecora Andrew L Compositions and methods for treating progressive myocardial injury due to a vascular insufficiency
JP5705127B2 (ja) * 2008-12-03 2015-04-22 アモーサイト インコーポレイテッド 梗塞領域灌流改善組成物および血管損傷修復の方法
CA2778664C (en) * 2009-10-23 2019-12-24 Amorcyte, Inc. Compositions and methods for treating progressive myocardial injury due to a vascular insufficiency
US9533010B2 (en) 2011-10-31 2017-01-03 Amorcyte, Llc Compositions and methods for treating progressive myocardial injury due to a vascular insufficiency
WO2015073677A1 (en) * 2013-11-14 2015-05-21 The University Of Miami Non-expanded post-natal multilineage-inducible cells
US20150228115A1 (en) * 2014-02-10 2015-08-13 Kabushiki Kaisha Toshiba Medical-image processing apparatus and medical-image diagnostic apparatus
EP3247808B1 (en) 2015-01-21 2021-05-05 Fred Hutchinson Cancer Research Center Point-of-care and/or portable platform for gene therapy
CN109996535B (zh) * 2016-12-28 2024-02-23 日本乐敦制药株式会社 细胞药物组合物、疾病治疗用试剂盒和细胞悬浮用溶液
JP2021521193A (ja) * 2018-04-18 2021-08-26 スンマ ヘルスSumma Health 虚血および心筋症の処置のための組成物および方法

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CA1179942A (en) 1981-10-06 1984-12-27 Lubert Stryer Fluorescent conjugates for analysis of molecules and cells
US4859582A (en) 1981-10-06 1989-08-22 The Board Of Trustees Of The Leland Stanford Jr. University Fluorescent conjugates for analysis of molecules and cells
US4965204A (en) 1984-02-06 1990-10-23 The Johns Hopkins University Human stem cells and monoclonal antibodies
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FR2596413B1 (fr) 1986-03-27 1988-06-10 Merieux Inst Nouveaux milieux de culture de bacteries appartenant au genre bordetella, contenant des derives etherifies de polymeres de d-glucose, et leur application
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WO2003099320A1 (en) * 2002-05-24 2003-12-04 Zensun (Shanghai) Sci-Tech.Ltd Neuregulin based methods and compositions for treating viral myocarditis and dilated cardiomyopathy
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Also Published As

Publication number Publication date
EP3170891A1 (en) 2017-05-24
EP3170891B1 (en) 2020-11-25
GB2487339A (en) 2012-07-18
JP2020105216A (ja) 2020-07-09
ES2845691T3 (es) 2021-07-27
CA2778664C (en) 2019-12-24
GB201208457D0 (en) 2012-06-27
JP6761236B2 (ja) 2020-09-23
EP2491114A4 (en) 2013-11-06
JP2016029095A (ja) 2016-03-03
EP2491114A1 (en) 2012-08-29
JP2018043991A (ja) 2018-03-22
WO2011050266A1 (en) 2011-04-28
EP2491114B1 (en) 2016-11-23
CA2778664A1 (en) 2011-04-28
JP2014037433A (ja) 2014-02-27
JP5709880B2 (ja) 2015-04-30
JP2013508408A (ja) 2013-03-07
EP2491114B8 (en) 2017-01-25

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