ES259882A1 - Procedure for the preparation of amino-norcanfanderivados N-replaced (Machine-translation by Google Translate, not legally binding)
- Google Patents
Procedure for the preparation of amino-norcanfanderivados N-replaced (Machine-translation by Google Translate, not legally binding)
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Merck KGaA
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E Merck AG
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Publication of ES259882A1publicationCriticalpatent/ES259882A1/en
Organic Low-Molecular-Weight Compounds And Preparation Thereof
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Peptides Or Proteins
(AREA)
Abstract
Procedure for the preparation of analeptically effective, N-substituted amino-norcanfanderivatives, characterized in that in a compound of formula I *** R1 = aryl, aralkyl, cycloalkyl or heterocyclic radical that can be optionally substituted one or more times, R2 = H, alkyl, aryl, x = 1 or 2, for which the individual radicals have only 15 carbon atoms. According to the known alkylation methods, one or both hydrogen atoms of the amino group are substituted by alkyl radicals aralkyl or cycloalkyl, to which effect the individual radicals have only 15 carbon atoms and the alkyl radicals can be linked, possibly by a subsequent heteroatom, to each other, to the extent that both hydrogen atoms must not be substituted simultaneously by methyl, when R1 = phenyl, R2 = H, and x = 1 and because an amine thus obtained is transformed in a manner known per se into a quaternary ammonium compound, or in an acid addition salt that does not present a physiological problem. (Machine-translation by Google Translate, not legally binding)
ES0259882A1959-08-011960-07-26Procedure for the preparation of amino-norcanfanderivados N-replaced (Machine-translation by Google Translate, not legally binding)
ExpiredES259882A1
(en)
Procedure for the preparation of new derivatives of penicilanic amino-6 acid and its toxic salts (Machine-translation by Google Translate, not legally binding)
A procedure for the preparation of quaternary salts of basic esters of the beta- (i-naftil) -acrilic acid. (Machine-translation by Google Translate, not legally binding)