ES2586979A1 - Vacunas vivas atenuadas de staphylococcus aureus - Google Patents

Vacunas vivas atenuadas de staphylococcus aureus Download PDF

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Publication number
ES2586979A1
ES2586979A1 ES201530508A ES201530508A ES2586979A1 ES 2586979 A1 ES2586979 A1 ES 2586979A1 ES 201530508 A ES201530508 A ES 201530508A ES 201530508 A ES201530508 A ES 201530508A ES 2586979 A1 ES2586979 A1 ES 2586979A1
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ES
Spain
Prior art keywords
translation
machine
legally binding
google translate
staphylococcus aureus
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
ES201530508A
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English (en)
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ES2586979B1 (es
Inventor
Germán BOU ARÉVALO
Mirian MOSCOSO NAYA
Patricia García Fernández
Maria Clara POVOA CABRAL
Silvia RODRÍGUEZ LOMBARDERO
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
FUNDACION PROFESOR NOVOA SANTOS
Servicio Galego de Saude (Sergas)
Original Assignee
FUNDACION PROFESOR NOVOA SANTOS
Servicio Galego de Saude (Sergas)
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Application filed by FUNDACION PROFESOR NOVOA SANTOS, Servicio Galego de Saude (Sergas) filed Critical FUNDACION PROFESOR NOVOA SANTOS
Priority to ES201530508A priority Critical patent/ES2586979B1/es
Publication of ES2586979A1 publication Critical patent/ES2586979A1/es
Application granted granted Critical
Publication of ES2586979B1 publication Critical patent/ES2586979B1/es
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/085—Staphylococcus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/40—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum bacterial

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Veterinary Medicine (AREA)
  • Zoology (AREA)
  • Epidemiology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Mycology (AREA)
  • Immunology (AREA)
  • Biotechnology (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Biomedical Technology (AREA)
  • Virology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

La presente invención proporciona cepas bacterianas de S. aureus auxótrofas para D-alanina, útiles como vacunas en mamíferos, suficientemente avirulentas (atenuadas) como para evitar efectos patológicos inaceptables, sin sustancialmente ninguna probabilidad de revertir a una cepa de tipo salvaje virulenta y capaces de inducir un nivel suficiente de inmunidad en el huésped como para inducir una protección aceptable frente a una infección por S. aureus en un mamífero.
ES201530508A 2015-04-15 2015-04-15 Vacunas vivas atenuadas de staphylococcus aureus Expired - Fee Related ES2586979B1 (es)

Priority Applications (1)

Application Number Priority Date Filing Date Title
ES201530508A ES2586979B1 (es) 2015-04-15 2015-04-15 Vacunas vivas atenuadas de staphylococcus aureus

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES201530508A ES2586979B1 (es) 2015-04-15 2015-04-15 Vacunas vivas atenuadas de staphylococcus aureus

Publications (2)

Publication Number Publication Date
ES2586979A1 true ES2586979A1 (es) 2016-10-19
ES2586979B1 ES2586979B1 (es) 2017-07-25

Family

ID=57127808

Family Applications (1)

Application Number Title Priority Date Filing Date
ES201530508A Expired - Fee Related ES2586979B1 (es) 2015-04-15 2015-04-15 Vacunas vivas atenuadas de staphylococcus aureus

Country Status (1)

Country Link
ES (1) ES2586979B1 (es)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3735268A4 (en) * 2018-01-05 2021-12-22 Azitra, Inc. AUXOTROPHIC STRAINS OF STAPHYLOCOCCUS BACTERIA
WO2022018268A1 (en) * 2020-07-24 2022-01-27 Basf Se Alanine racemase double deletion and transcomplementation
JP2022513599A (ja) * 2018-11-16 2022-02-09 アジトラ インコーポレーテッド Ｓｔａｐｈｙｌｏｃｏｃｃｕｓ細菌の栄養要求性株

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3735268A4 (en) * 2018-01-05 2021-12-22 Azitra, Inc. AUXOTROPHIC STRAINS OF STAPHYLOCOCCUS BACTERIA
JP2022513599A (ja) * 2018-11-16 2022-02-09 アジトラ インコーポレーテッド Ｓｔａｐｈｙｌｏｃｏｃｃｕｓ細菌の栄養要求性株
WO2022018268A1 (en) * 2020-07-24 2022-01-27 Basf Se Alanine racemase double deletion and transcomplementation

Also Published As

Publication number Publication date
ES2586979B1 (es) 2017-07-25

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