ES2550522B1 - Food supplement for male fertility - Google Patents
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- ES2550522B1 ES2550522B1 ES201531146A ES201531146A ES2550522B1 ES 2550522 B1 ES2550522 B1 ES 2550522B1 ES 201531146 A ES201531146 A ES 201531146A ES 201531146 A ES201531146 A ES 201531146A ES 2550522 B1 ES2550522 B1 ES 2550522B1
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/16—Inorganic salts, minerals or trace elements
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/115—Fatty acids or derivatives thereof; Fats or oils
- A23L33/12—Fatty acids or derivatives thereof
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/135—Bacteria or derivatives thereof, e.g. probiotics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/12—Ketones
- A61K31/122—Ketones having the oxygen directly attached to a ring, e.g. quinones, vitamin K1, anthralin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
- A61K31/202—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids having three or more double bonds, e.g. linolenic
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/04—Sulfur, selenium or tellurium; Compounds thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/24—Heavy metals; Compounds thereof
- A61K33/30—Zinc; Compounds thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/66—Microorganisms or materials therefrom
- A61K35/74—Bacteria
- A61K35/741—Probiotics
- A61K35/744—Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
- A61K35/747—Lactobacilli, e.g. L. acidophilus or L. brevis
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Abstract
Complemento alimenticio para la fertilidad masculina que comprende una asociación de antioxidantes y energizantes constituida por ácido docosahexaenoico, Coenzima Q10, Cinc y Selenio y una mezcla de agentes probióticos constituida por Lactobacillus Plantarum y Lactobacillus Crispatus.Food supplement for male fertility comprising an association of antioxidants and energizers consisting of docosahexaenoic acid, Coenzyme Q10, Zinc and Selenium and a mixture of probiotic agents consisting of Lactobacillus Plantarum and Lactobacillus Crispatus.
Description
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DESCRIPCIONDESCRIPTION
Complemento alimenticio para la fertilidad masculina Campo de la invencionFood supplement for male fertility Field of the invention
La presente invencion se refiere al uso de probioticos en la composition de complementos alimenticios destinados a mejorar la fertilidad masculina.The present invention relates to the use of probiotics in the composition of food supplements intended to improve male fertility.
Antecedentes de la invencionBackground of the invention
Los Complementos alimenticios son productos cuyo fin es complementar una dieta normal y consisten en fuentes concentradas de nutrientes o de otras sustancias que tienen un efecto nutricional o fisiologico, en forma simple o combinada. Son comercializados en forma dosificada, es decir capsulas, pastillas, tabletas, pfldoras que deben tomarse en pequenas cantidades unitarias.Food supplements are products whose purpose is to complement a normal diet and consist of concentrated sources of nutrients or other substances that have a nutritional or physiological effect, in simple or combined form. They are marketed in a dosage form, that is capsules, pills, tablets, pills that must be taken in small unit quantities.
No son medicamentos, mejoran el bienestar pero no curan ninguna enfermedad. Estan dirigidos a personas con buena salud y no a enfermos por lo que no necesitan prescripcion medica.They are not medications, improve well-being but do not cure any disease. They are aimed at people in good health and not sick people so they do not need a prescription.
De entre la gran variedad de complementos alimenticios comercializados distinguimos los destinados a potenciar la fertilidad masculina, que tienen como finalidad la mejora de la calidad del esperma.Among the wide variety of food supplements marketed distinguish those aimed at enhancing male fertility, which are aimed at improving sperm quality.
La patente austriaca AT 503219 describe una preparation para mejorar la calidad del esperma de un individuo que contiene L-carnitina, coenzima Q10, a-tocoferol, sulfato de cinc o cloruro de cinc, acido folico, selenio, glutation y L-arginina.Austrian patent AT 503219 describes a preparation for improving the sperm quality of an individual containing L-carnitine, coenzyme Q10, a-tocopherol, zinc sulfate or zinc chloride, folic acid, selenium, glutathione and L-arginine.
La solicitud de patente internacional WO 03/086080 describe una formula farmaceutica y un complemento alimenticio con una actividad de fomento de la fertilidad en el hombre (sexo masculino), que contiene vitaminas C y E, selenio, acido ferulico, cinc, vitaminas del grupo B y, en su caso, L-carnitina y coenzima Q10. Nutrientes tales como la L-carnitina, las vitaminas del grupo B y el cinc desempenan un papel en el metabolismo y la formacion del esperma.International patent application WO 03/086080 describes a pharmaceutical formula and a food supplement with a fertility promotion activity in men (male), which contains vitamins C and E, selenium, ferulic acid, zinc, vitamins of the group B and, where appropriate, L-carnitine and coenzyme Q10. Nutrients such as L-carnitine, vitamins of group B and zinc play a role in the metabolism and formation of sperm.
La patente francesa FR 0503998 describe un complemento alimenticio destinado a la fertilidad masculina que comprende entro otros Vitamina C, Vitaminas del grupo B, Coenzima Q10, Cinc en forma de sales o complejos, Selenio, Acidos grasos insaturados y en su caso Carnitina.French patent FR 0503998 describes a food supplement intended for male fertility which comprises other Vitamin C, Vitamins of group B, Coenzyme Q10, Zinc in the form of salts or complexes, Selenium, Unsaturated fatty acids and, if applicable, Carnitine.
La vitamina C ayuda a mejorar la movilidad de los espermatozoides evitando que se aglutinen. Ademas, gracias a su poder antioxidante contribuye a luchar contra los radicales libres queVitamin C helps improve sperm motility by preventing them from clumping together. In addition, thanks to its antioxidant power it helps to fight against free radicals that
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afectan la fertilidad.Affect fertility.
La vitamina B12 aumenta el conteo de espermatozoides y por lo tanto aumenta tambien las posibilidades de concebir.Vitamin B12 increases sperm count and therefore also increases the chances of conceiving.
La coenzima Q10 es un componente de la cadena de transporte de electrones y participa en la respiracion celular, generando energia. Tambien actua como un potente antioxidante. Cuando se es joven, el cuerpo puede sintetizar CoQ10. Con la edad, situaciones de estres, y determinadas patolog^as, disminuye la capacidad de smtesis de este enzima. Entonces las personas pueden no ser capaces de generar la suficiente cantidad de esta coenzima, por lo que debe ser suministrada de forma externa y adicional a la dieta. La administracion de Coenzima Q10 a varones con problemas de fertilidad y anomalias en su esperma, ha demostrado una mejora significativa del numero de espermatozoides, la concentracion y la motilidad.Coenzyme Q10 is a component of the electron transport chain and participates in cellular respiration, generating energy. It also acts as a powerful antioxidant. When you are young, the body can synthesize CoQ10. With age, stress situations, and certain pathologies, the ability to synthesize this enzyme decreases. Then people may not be able to generate enough of this coenzyme, so it must be supplied externally and in addition to the diet. The administration of Coenzyme Q10 to men with fertility problems and abnormalities in their sperm, has shown a significant improvement in sperm count, concentration and motility.
El cinc es un oligoelemento necesario en la salud humana. Este elemento se encuentra en segundo lugar, despues del hierro, por su concentracion en el organismo y podemos encontrar encontrarlo en todas las celulas. Es necesario para el normal funcionamiento del sistema inmunitario, y juega un papel fundamental en la division y crecimiento de las celulas.Zinc is a necessary trace element in human health. This element is in second place, after iron, because of its concentration in the organism and we can find it found in all cells. It is necessary for the normal functioning of the immune system, and plays a fundamental role in the division and growth of cells.
La administracion de cinc a varones con disminucion en la motilidad de los espermatozoides, se asocia a un aumento de la motilidad de los mismos, asi como de la integridad de la membrana de los espermatozoides.The administration of zinc to men with decreased sperm motility is associated with an increase in their motility, as well as the integrity of the sperm membrane.
El Selenio es un oligoelemento esencial, que debe de ser ingerido con la dieta. El organismo solo precisa Selenio en pequenas cantidades. La principal funcion del Selenio es la de contribuir en la produccion de los enzimas antioxidantes, los cuales juegan un papel importante en la prevencion del dano celular.Selenium is an essential trace element, which must be ingested with the diet. The organism only needs Selenium in small quantities. The main function of Selenium is to contribute to the production of antioxidant enzymes, which play an important role in the prevention of cell damage.
La administracion de Selenio a varones con deficit en la motilidad de espermatozoides, ha demostrado una mejora significativa de la motilidad espermatica. Se registra, asimismo, una tendencia a un mejor resultado en las tasas de embarazo.The administration of Selenium to men with sperm motility deficit has shown a significant improvement in sperm motility. There is also a trend towards a better result in pregnancy rates.
Los acidos grasos insaturados son componentes estructurales presentes en todo ser viviente, plantas y animales. Estos acidos grasos se encuentran en la doble capa de fosfolipidos de todas las membranas celulares y de los organelos citoplasmaticos, y confieren a la membrana propiedades diferentes de acuerdo con el acido graso predominante. A traves de la membrana celular se establecen las comunicaciones intercelulares; asi la expresion de receptores, lasUnsaturated fatty acids are structural components present in every living being, plants and animals. These fatty acids are found in the double phospholipid layer of all cell membranes and cytoplasmic organelles, and give the membrane different properties according to the predominant fatty acid. Intercellular communications are established through the cell membrane; so the expression of receptors, the
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protemas de membrana, la smtesis de prostaciclinas, tromboxanos y leucotrienos y los ligandos de receptores nucleares, pueden variar en sus caracteristicas funcionales en dependencia de los acidos grasos que predominan en los fosfoKpidos de membrana.membrane proteins, the synthesis of prostacyclines, thromboxanes and leukotrienes and the nuclear receptor ligands, may vary in their functional characteristics depending on the fatty acids that predominate in the membrane phosphokids.
Los acidos grasos omega 3 son acidos grasos esenciales poliinsaturados, que se encuentran en alta proportion en los tejidos de ciertos pescados, y en algunas fuentes vegetales.Omega 3 fatty acids are polyunsaturated essential fatty acids, which are found in high proportion in the tissues of certain fish, and in some plant sources.
El ser humano no puede generar acidos a partir de otros componentes, por lo que los acidos omega 3 deben ingerirse con la dieta.The human being cannot generate acids from other components, so omega 3 acids must be ingested with the diet.
Los acidos omega-3 tienen diversos efectos entre ellos se destaca, como aumentar el tiempo de coagulation de la sangre, efectos beneficos sobre el cerebro, tambien durante el embarazo puede tener influencia en el desarrollo del feto. Han demostrado poseer un efecto antidepresivo, y mejorar el rendimiento escolar en ninos con deficit de atencion o hiperactividad.Omega-3 acids have various effects among them, such as increasing the time of blood coagulation, beneficial effects on the brain, also during pregnancy can have an influence on the development of the fetus. They have been shown to have an antidepressant effect, and improve school performance in children with attention deficit hyperactivity disorder.
Existen seis tipos diferentes de acido omega 3, el acido docosahexaenoico (DHA) es uno de ellos.There are six different types of omega 3 acid, docosahexaenoic acid (DHA) is one of them.
El DHA tiene un efecto positivo sobre la estructura y funcion de las membranas y es un precursor de metabolitos anti-inflamatorios y neuroprotectores. Se usa como complemento alimenticio en diversos preparados, indicado para mejorar la funcion cognitiva y visual, deficit de atencion, mejora de la funcion espermatica, desarrollo del feto etc.DHA has a positive effect on the structure and function of membranes and is a precursor of anti-inflammatory and neuroprotective metabolites. It is used as a nutritional supplement in various preparations, indicated to improve cognitive and visual function, attention deficit, improvement of sperm function, development of the fetus etc.
En el hombre, los espermatozoides tienen una elevada concentration de lipidos. Del total de acidos grasos contenidos en el espermatozoide, mas del 20% corresponde a DHA.In man, sperm have a high concentration of lipids. Of the total fatty acids contained in the sperm, more than 20% corresponds to DHA.
Cuando disminuya la concentracion de DHA a nivel seminal, se observa una menor concentracion y movilidad espermatica. Adicionalmente se incrementa de forma notoria la presencia de espermatozoides con formas atipicas. Esta disminucion del DHA provoca una dificultad en la probabilidad de conseguir un embarazo.When the concentration of DHA decreases at the seminal level, a lower concentration and sperm mobility is observed. Additionally, the presence of sperm with atypical forms is markedly increased. This decrease in DHA causes a difficulty in the probability of getting a pregnancy.
El aporte de DHA de forma externa e intensiva, permite corregir esta deficiencia y proporcionar un aporte adicional de DHA que se incorpora a los espermatozoides, mejorando la calidad y concentracion de espermatozoides en el varon.The contribution of DHA externally and intensively, allows to correct this deficiency and provide an additional contribution of DHA that is incorporated into the sperm, improving the quality and concentration of sperm in the male.
La Carnitina es una sustancia producida de forma natural por el organismo y su carencia afecta a la fertilidad masculina. La L-carnitina cumple un rol importante en la production, maduracion y motilidad de los espermatozoides.Carnitine is a substance produced naturally by the body and its lack affects male fertility. L-carnitine plays an important role in the production, maturation and motility of sperm.
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Los componentes de estos complementos alimenticios tienen una finalidad centrada en la mejora de calidad y cantidad de esperma, sin embargo una de las posibles causas de infertilidad es la incompatibilidad entre el esperma y el medio genital femenino.The components of these food supplements have a purpose focused on improving the quality and quantity of sperm, however one of the possible causes of infertility is the incompatibility between the sperm and the female genital environment.
No se han descrito formulaciones de complementos alimenticios destinados a la mejora de la fertilidad masculina que incorporen probioticos.Formulations of food supplements intended to improve male fertility that incorporate probiotics have not been described.
Descripcion de la invencionDescription of the invention
La invencion se refiere un complemento alimenticio para la fertilidad masculina que incluye probioticos con la finalidad de compatibilizar el esperma con el medio genital femenino.The invention relates to a nutritional supplement for male fertility that includes probiotics in order to make sperm compatible with the female genital medium.
El nuevo complemento alimenticio comprende una asociacion de:The new food supplement includes an association of:
a) Una mezcla antioxidantes y energizantes constituida por acido docosahexaenoico, Coenzima Q10, Cinc y Selenio.a) An antioxidant and energizing mixture consisting of docosahexaenoic acid, Coenzyme Q10, Zinc and Selenium.
b) Una mezcla de agentes probioticos constituida por Lactobacillus Plantarum y Lactobacillus Crispatus.b) A mixture of probiotic agents consisting of Lactobacillus Plantarum and Lactobacillus Crispatus.
La primera mezcla tiene objeto la mejora de calidad y cantidad de esperma, mientras que la segunda esta destinada preservar el esperma de bacterias y compatibilizarlo con el medio genital femenino.The first mixture is aimed at improving the quality and quantity of sperm, while the second is intended to preserve the sperm of bacteria and make it compatible with the female genital environment.
Los lactobacilos son bacterias anaerobicas gram+. Este tipo de probioticos han sido descritos como bacterias comunes en el semen, y se ha encontrado que tienen un impacto positivo en los criterios clmicos de calidad del semen, como son la morfologia de los espermatozoides y su concentration.Lactobacilli are anaerobic gram + bacteria. These types of probiotics have been described as common bacteria in the semen, and have been found to have a positive impact on the semen quality criteria, such as sperm morphology and concentration.
Diversos estudios han identificado la presencia de bacterias como un papel destacado en hombres infertiles.Several studies have identified the presence of bacteria as a prominent role in infertile men.
En individuos fertiles, los lactobacilos son la microbiota mas abundante en el semen. Estos juegan un papel preponderante en el mantenimiento y calidad del semen al tiempo que ejercen un papel fundamental reduciendo el efecto negativo de especies como la Prevotella y la Pseudomonas. Las infecciones bacterianas en el aparato genitourinario del hombre son muy frecuentes y contribuyen de forma destacada al deterioro y calidad del esperma del hombre.In fertile individuals, lactobacilli are the most abundant microbiota in semen. These play a preponderant role in the maintenance and quality of semen while they play a fundamental role in reducing the negative effect of species such as Prevotella and Pseudomonas. Bacterial infections in the genitourinary tract of man are very frequent and contribute significantly to the deterioration and quality of sperm in man.
El Lactobacillus Plantarum esta presente en la mucosa vaginal y ejerce un efecto inhibiendo la agregacion del esperma junto con Escherichia Coli a las celulas epiteliales de la vagina.Lactobacillus Plantarum is present in the vaginal mucosa and exerts an effect by inhibiting the addition of sperm along with Escherichia Coli to the epithelial cells of the vagina.
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Por lo tanto Lactobacillus Plantarum ejerce un efecto beneficioso sobre la salud y calidad del semen masculino y contribuye al normal ecosistema de la flora vaginal.Therefore Lactobacillus Plantarum exerts a beneficial effect on the health and quality of male semen and contributes to the normal ecosystem of vaginal flora.
La presencia de Lactobacillus Crispatus ha demostrado un efecto positivo en la concentration espermatica, en la cantidad de leucocitos, de inmunoglobulina A, asi como la morfo^a de los espermatozoides. En condiciones normales, el Lactobacillus Crispatus tambien esta presente en la flora vaginal.The presence of Lactobacillus Crispatus has shown a positive effect on sperm concentration, on the amount of leukocytes, immunoglobulin A, as well as the morpho of the sperm. Under normal conditions, Lactobacillus Crispatus is also present in the vaginal flora.
El Lactobacillus Crispatus reduce la viabilidad de microorganismos patogenos como Gardnerella Vaginalis o Prevotella Bivia, restaurando el normal ecosistema de probioticos en la mucosa vaginal y desplazando la colonizacion de microorganismos patogenos.Lactobacillus Crispatus reduces the viability of pathogenic microorganisms such as Gardnerella Vaginalis or Prevotella Bivia, restoring the normal ecosystem of probiotics in the vaginal mucosa and displacing the colonization of pathogenic microorganisms.
En consecuencia Lactobacillus Crispatus tiene un papel potencial para mantener el ecosistema del semen, de su calidad asi como jugar un papel de mantenimiento en el ecosistema vaginal, regulando la capacidad fertil en el hombre.Consequently Lactobacillus Crispatus has a potential role to maintain the semen ecosystem, its quality as well as play a maintenance role in the vaginal ecosystem, regulating the fertility capacity in man.
El complemento alimenticio esta formulado para administrarse por via oral. Por lo tanto, puede presentarse en forma de capsula, comprimido, granulado, ventajosamente en forma de capsula. Si el complemento alimenticio se presenta en forma de capsula blanda o capsula, la envuelta de dichas capsulas blandas o dichas capsulas puede contener especialmente gelatina animal, como gelatina de pescado, glicerina o un material de origen vegetal, como un derivado de celulosa o de almidon, o una protema vegetal. Si el complemento alimenticio se presenta en forma de capsula, comprimido o granulado, la mezcla de activos puede fijarse en un soporte polvoriento, como sflice, celulosa y maltodextrina.The food supplement is formulated to be administered orally. Therefore, it can be presented in capsule form, compressed, granulated, advantageously in capsule form. If the food supplement is in the form of a soft capsule or capsule, the shell of said soft capsules or said capsules may contain especially animal gelatin, such as fish jelly, glycerin or a material of plant origin, such as a cellulose or starch derivative , or a vegetable protein. If the food supplement is in the form of a capsule, tablet or granulate, the active mixture can be fixed on a dusty support, such as silica, cellulose and maltodextrin.
El complemento alimenticio de la invention responde preferiblemente a la siguiente composition ponderal:The food supplement of the invention preferably responds to the following weight composition:
Para una capsulaFor a capsule
- acido docosahexaenoico Docosahexaenoic acid
- 470 - 525 mg 470-525 mg
- Coenzima Q10 Coenzyme Q10
- 95 -110 mg 95-110 mg
- Cinc Zinc
- 12 -14 mg 12-14 mg
- Selenio Selenium
- 0,04 - 0,07 mg 0.04 - 0.07 mg
- Lactobacillus Plantarum Lactobacillus Plantarum
- 5x1010 UFC 5x1010 UFC
- Lactobacillus Crispatus 5x1010UFC Para esta capsula en particular la dosis recomendada es de dos unidades al d^a.- Lactobacillus Crispatus 5x1010UFC For this particular capsule the recommended dose is two units per day.
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Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES201531146A ES2550522B1 (en) | 2015-07-31 | 2015-07-31 | Food supplement for male fertility |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES201531146A ES2550522B1 (en) | 2015-07-31 | 2015-07-31 | Food supplement for male fertility |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES2550522A1 ES2550522A1 (en) | 2015-11-10 |
| ES2550522B1 true ES2550522B1 (en) | 2016-09-06 |
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ID=54364920
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES201531146A Active ES2550522B1 (en) | 2015-07-31 | 2015-07-31 | Food supplement for male fertility |
Country Status (1)
| Country | Link |
|---|---|
| ES (1) | ES2550522B1 (en) |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2884692B1 (en) * | 2005-04-21 | 2009-08-14 | Formquest Ltd | FOOD SUPPLEMENT COMPRISING AN ASSOCIATION OF ANTIOXIDANT AGENTS AND CARNITINE, OBTAINED BY ENDOGENEOUS OR EXOGENOUS SYNTHESIS, AS AID FOR FERTILITY IN MAN AND WOMEN |
| WO2007140621A1 (en) * | 2006-06-09 | 2007-12-13 | Nutravital Inc. | Probiotic compositions and uses thereof |
| US20140205618A1 (en) * | 2012-12-28 | 2014-07-24 | CortControl, Inc. | Human fertility enhancement with cortisol reduction food |
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| Publication number | Publication date |
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| ES2550522A1 (en) | 2015-11-10 |
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