ES2534556T3 - Bacteria Lawsonia intracellularis de un nuevo serotipo, vacuna basada en esa bacteria, anticuerpos adecuados para diagnosticar el nuevo serotipo de Lawsonia intracellularis e hibridomas para producir dichos anticuerpos - Google Patents

Bacteria Lawsonia intracellularis de un nuevo serotipo, vacuna basada en esa bacteria, anticuerpos adecuados para diagnosticar el nuevo serotipo de Lawsonia intracellularis e hibridomas para producir dichos anticuerpos Download PDF

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Publication number
ES2534556T3
ES2534556T3 ES09800038.3T ES09800038T ES2534556T3 ES 2534556 T3 ES2534556 T3 ES 2534556T3 ES 09800038 T ES09800038 T ES 09800038T ES 2534556 T3 ES2534556 T3 ES 2534556T3
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Spain
Prior art keywords
lawsonia intracellularis
antibodies
new serotype
bacterium
hybridomas
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ES09800038.3T
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English (en)
Inventor
Mohamad Morsey
Antonius Arnoldus Christiaan Jacobs
Carla Christina Schrier
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Intervet International BV
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Intervet International BV
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/105—Delta proteobacteriales, e.g. Lawsonia; Epsilon proteobacteriales, e.g. campylobacter, helicobacter
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C12N1/205—Bacterial isolates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/12—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/52—Bacterial cells; Fungal cells; Protozoal cells
    • A61K2039/521—Bacterial cells; Fungal cells; Protozoal cells inactivated (killed)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55566—Emulsions, e.g. Freund's adjuvant, MF59
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Microbiology (AREA)
  • Zoology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Wood Science & Technology (AREA)
  • Biochemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Virology (AREA)
  • General Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Molecular Biology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biomedical Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

Bacteria Lawsonia intracellularis de un serotipo que es reactivo con el anticuerpo monoclonal INT-LIC-02-02 tal como el producido por el hibridoma INT-LIC-02-02 depositado en la Colección Nacional de Cultivos de Microorganismos del Instituto Pasteur de París, Francia, con el nº CNCM I-4049, caracterizada por que no es reactiva con el anticuerpo INT-LIC-01-28 tal como el producido mediante el hibridoma INT-LIC-01-28 depositado en la Colección Nacional de Cultivos de Microorganismos del Instituto Pasteur de París, Francia, con el nº CNCM I- 4048.

Description

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Claims (1)

  1. imagen1
ES09800038.3T 2008-07-22 2009-07-20 Bacteria Lawsonia intracellularis de un nuevo serotipo, vacuna basada en esa bacteria, anticuerpos adecuados para diagnosticar el nuevo serotipo de Lawsonia intracellularis e hibridomas para producir dichos anticuerpos Active ES2534556T3 (es)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US82552P 1998-04-21
US8255208P 2008-07-22 2008-07-22
EP08162299 2008-08-13
EP08162299 2008-08-13
PCT/EP2009/059279 WO2010010055A1 (en) 2008-07-22 2009-07-20 Lawsonia intracellularis bacterium of a novel serotype, vaccine based on that bacterium, antibodies suitable for diagnosing the novel lawsonia intracellularis serotype and hybridomas for producing the said antibodies

Publications (1)

Publication Number Publication Date
ES2534556T3 true ES2534556T3 (es) 2015-04-24

Family

ID=40254546

Family Applications (1)

Application Number Title Priority Date Filing Date
ES09800038.3T Active ES2534556T3 (es) 2008-07-22 2009-07-20 Bacteria Lawsonia intracellularis de un nuevo serotipo, vacuna basada en esa bacteria, anticuerpos adecuados para diagnosticar el nuevo serotipo de Lawsonia intracellularis e hibridomas para producir dichos anticuerpos

Country Status (6)

Country Link
US (1) US8557254B2 (es)
EP (1) EP2318041B1 (es)
JP (1) JP5723772B2 (es)
ES (1) ES2534556T3 (es)
TW (1) TW201016231A (es)
WO (1) WO2010010055A1 (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2012506858A (ja) 2008-10-23 2012-03-22 インターベット インターナショナル ベー． フェー． Ｌａｗｓｏｎｉａｉｎｔｒａｃｅｌｌｕｌａｒｉｓワクチン

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5885823A (en) * 1995-06-05 1999-03-23 Nobl Laboratories, Inc. Lawsonia intracellularis cultivation, anti-Lawsonia intracellularis vaccines and diagnostic agents
ATE329031T1 (de) * 1995-11-30 2006-06-15 Agriculture Victoria Serv Pty Therapeutische zusammensetzungen zur behandlung von lawsonia intracellularis infektionen
ES2360225T3 (es) * 2000-12-20 2011-06-02 Intervet International Bv Vacuna contra lawsonia intracellularis.
JP2006528882A (ja) * 2003-07-25 2006-12-28 ベーリンガー インゲルハイム フェトメディカ インコーポレイテッド 欧州起源のローソニア・イントラセルラリス並びにそのワクチン、診断薬及び使用方法
DE602005021750D1 (de) 2004-01-22 2010-07-22 Intervet Int Bv Impfstoffe mit lawsoniaintrazellularis-untereinheit
MY146476A (en) * 2004-06-24 2012-08-15 Boehringer Ingelheim Vetmed Method of diagnosing lawsonia intracellularis
US7550270B2 (en) * 2004-08-13 2009-06-23 Boehringer Ingelheim Vetmedica, Inc. Ileitis diagnostic assay
US20070212373A1 (en) * 2004-12-08 2007-09-13 Akzo Nobel N.V. Lawsonia Intracellularis 26 Kd Subunit Vaccine
US8398994B2 (en) * 2005-07-15 2013-03-19 Boehringer Ingelheim Vetmedica, Inc. Lawsonia vaccine and methods of use thereof
US8470336B2 (en) * 2006-05-25 2013-06-25 Boehringer Ingelheim Vetmedica, Inc. Vaccination of young animals against Lawsonia intracellularis infections
TWI449533B (zh) * 2008-04-18 2014-08-21 Intervet Int Bv 防備胞內勞森菌（Ｌａｗｓｏｎｉａ ｉｎｔｒａｃｅｌｌｕｌａｒｉｓ）、豬肺炎黴漿菌（Ｍｙｃｏｐｌａｓｍａ ｈｙｏｐｎｅｕｍｏｎｉａｅ）及豬環狀病毒（Ｐｏｒｃｉｎｅ ｃｉｒｃｏ ｖｉｒｕｓ）用疫苗

Also Published As

Publication number Publication date
US20110129500A1 (en) 2011-06-02
JP5723772B2 (ja) 2015-05-27
TW201016231A (en) 2010-05-01
WO2010010055A1 (en) 2010-01-28
EP2318041B1 (en) 2015-02-25
US8557254B2 (en) 2013-10-15
JP2011528563A (ja) 2011-11-24
EP2318041A1 (en) 2011-05-11

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