Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Wyeth Holdings LLC
Original Assignee
American Cyanamid Co
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Filing date
Publication date
Application filed by American Cyanamid CofiledCriticalAmerican Cyanamid Co
Priority to ES0244819ApriorityCriticalpatent/ES244819A1/en
Publication of ES244819A1publicationCriticalpatent/ES244819A1/en
Organic Low-Molecular-Weight Compounds And Preparation Thereof
(AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds
(AREA)
Abstract
A method of preparing an acid addition salt of a 12a-deoxyanhydrotetracycline and the free base thereof, said free base having the general formula ** (See formula) ** where R1 is hydrogen or chloro and R2 is hydrogen or methyl, with the proviso that, when R1 is chloro, R2 is hydrogen, starting from a 12a-deoxytetracycline having the general formula ** (See formula) ** where R1 and R2 have the same significance as before, characterized in that a 12a-deoxytetracycline is treated with a dehydrating agent at a temperature between about 0º C and about 100º C, and, when an acid addition salt is obtained in this way, if you want, that salt is neutralized to produce the free base. (Machine-translation by Google Translate, not legally binding)
ES0244819A1958-10-211958-10-21A method of preparing a tetracycline salt (Machine-translation by Google Translate, not legally binding)
ExpiredES244819A1
(en)
Process for preparing a chemical composition comprising a complex consisting of 5-nitro-2-furaldehido and 2-oxazolidona (Machine-translation by Google Translate, not legally binding)