ES2421401T3 - Immunoassay procedure - Google Patents
Immunoassay procedureInfo
- Publication number
- ES2421401T3 ES2421401T3 ES09153124T ES09153124T ES2421401T3 ES 2421401 T3 ES2421401 T3 ES 2421401T3 ES 09153124 T ES09153124 T ES 09153124T ES 09153124 T ES09153124 T ES 09153124T ES 2421401 T3 ES2421401 T3 ES 2421401T3
- Authority
- ES
- Spain
- Prior art keywords
- membrane
- flow distributor
- blotting
- liquid
- support layer
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5025—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures for parallel transport of multiple samples
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5025—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures for parallel transport of multiple samples
- B01L3/50255—Multi-well filtration
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/508—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above
- B01L3/5085—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above for multiple samples, e.g. microtitration plates
- B01L3/50853—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above for multiple samples, e.g. microtitration plates with covers or lids
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/06—Fluid handling related problems
- B01L2200/0642—Filling fluids into wells by specific techniques
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/04—Closures and closing means
- B01L2300/041—Connecting closures to device or container
- B01L2300/043—Hinged closures
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/06—Auxiliary integrated devices, integrated components
- B01L2300/069—Absorbents; Gels to retain a fluid
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0809—Geometry, shape and general structure rectangular shaped
- B01L2300/0829—Multi-well plates; Microtitration plates
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/04—Moving fluids with specific forces or mechanical means
- B01L2400/0475—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure
- B01L2400/0487—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure fluid pressure, pneumatics
Abstract
The invention is directed to an apparatus useful in conducting detection of compounds on blotting membranes. The device is comprised of several layers including a porous support layer below the blotting membrane(s), a flow distributor above the blotting membrane(s) and optionally a well on the flow distributor to contain the liquid to the desired area and to allow for lower starting volumes of such liquid. Preferably, the flow distributor is a non-binding or low binding hydrophilic porous membrane such as a 0.22 micron membrane and the support layer is a grid or sintered porous material. The distributor and support are held together to form an envelope around the membrane(s). The use of a hinge, clips and other such devices is preferred in doing so.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US73299405P | 2005-11-03 | 2005-11-03 | |
US79545206P | 2006-04-27 | 2006-04-27 | |
US79553206P | 2006-04-27 | 2006-04-27 |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2421401T3 true ES2421401T3 (en) | 2013-09-02 |
Family
ID=37697833
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES06255513T Active ES2324834T3 (en) | 2005-11-03 | 2006-10-26 | IMMUNOENSAY PRODUCT AND PROCEDURE. |
ES09153124T Active ES2421401T3 (en) | 2005-11-03 | 2006-10-26 | Immunoassay procedure |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES06255513T Active ES2324834T3 (en) | 2005-11-03 | 2006-10-26 | IMMUNOENSAY PRODUCT AND PROCEDURE. |
Country Status (7)
Country | Link |
---|---|
US (3) | US8652421B2 (en) |
EP (2) | EP2072135B1 (en) |
JP (1) | JP4388945B2 (en) |
AT (1) | ATE427492T1 (en) |
DE (1) | DE602006006002D1 (en) |
ES (2) | ES2324834T3 (en) |
SG (1) | SG131911A1 (en) |
Families Citing this family (30)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8652421B2 (en) * | 2005-11-03 | 2014-02-18 | Emd Millipore Corporation | Immunoassay product and process |
EP1806176A1 (en) * | 2006-01-10 | 2007-07-11 | Casale Chemicals S.A. | Apparatus for the production of synthesis gas |
NZ584963A (en) | 2007-10-02 | 2012-11-30 | Theranos Inc | Modular Point-of-care devices as addressible assay units with tips of assay units having interior to immobilize reagents by capillary action |
CN102439131A (en) * | 2009-03-20 | 2012-05-02 | 新加坡科技研究局 | Devices for separating cells and methods of using them |
US8012770B2 (en) | 2009-07-31 | 2011-09-06 | Invisible Sentinel, Inc. | Device for detection of antigens and uses thereof |
US8524507B2 (en) * | 2009-08-19 | 2013-09-03 | The Cleveland Clinic Foundation | Method for detecting a target molecule in a biological sample |
WO2011044574A1 (en) | 2009-10-09 | 2011-04-14 | Invisible Sentinel | Device for detection of antigens and uses thereof |
US20120132560A1 (en) * | 2010-11-30 | 2012-05-31 | Ivan Hulka | Holding device for dried biological fluid spotting membrane and related methods |
JP5945282B2 (en) | 2011-01-21 | 2016-07-05 | セラノス, インコーポレイテッド | System and method for maximizing sample usage |
AU2012211141B2 (en) | 2011-01-27 | 2016-11-03 | Invisible Sentinel, Inc. | Analyte detection devices, multiplex and tabletop devices for detection of analytes, and uses thereof |
WO2012154905A1 (en) * | 2011-05-11 | 2012-11-15 | Emd Millipore Corporation | Immunoassay product and process |
US8840838B2 (en) | 2011-09-25 | 2014-09-23 | Theranos, Inc. | Centrifuge configurations |
US9664702B2 (en) | 2011-09-25 | 2017-05-30 | Theranos, Inc. | Fluid handling apparatus and configurations |
US8475739B2 (en) | 2011-09-25 | 2013-07-02 | Theranos, Inc. | Systems and methods for fluid handling |
US20140170735A1 (en) | 2011-09-25 | 2014-06-19 | Elizabeth A. Holmes | Systems and methods for multi-analysis |
US9268915B2 (en) | 2011-09-25 | 2016-02-23 | Theranos, Inc. | Systems and methods for diagnosis or treatment |
US9619627B2 (en) | 2011-09-25 | 2017-04-11 | Theranos, Inc. | Systems and methods for collecting and transmitting assay results |
US9632102B2 (en) | 2011-09-25 | 2017-04-25 | Theranos, Inc. | Systems and methods for multi-purpose analysis |
US9810704B2 (en) | 2013-02-18 | 2017-11-07 | Theranos, Inc. | Systems and methods for multi-analysis |
US9250229B2 (en) | 2011-09-25 | 2016-02-02 | Theranos, Inc. | Systems and methods for multi-analysis |
US10012664B2 (en) | 2011-09-25 | 2018-07-03 | Theranos Ip Company, Llc | Systems and methods for fluid and component handling |
US9347938B2 (en) | 2012-03-09 | 2016-05-24 | Invisible Sentinel, Inc. | Methods for detecting multiple analytes with a single signal |
US9308508B2 (en) | 2013-07-22 | 2016-04-12 | Kianoosh Peyvan | Sequential delivery device and method |
US10634590B2 (en) | 2014-03-11 | 2020-04-28 | Emd Millipore Corporation | IHC, tissue slide fluid exchange disposable and system |
US20160238627A1 (en) | 2015-02-13 | 2016-08-18 | Abbott Laboratories | Decapping and capping apparatus, systems and methods for use in diagnostic analyzers |
EP3600670A4 (en) * | 2017-03-22 | 2020-10-28 | Unchained Labs | Sample plates for buffer exchange and methods of manufacture |
WO2018209020A1 (en) * | 2017-05-10 | 2018-11-15 | Emd Millipore Corporation | Multiwell plate with variable compression seal |
CN109342741B (en) * | 2018-11-29 | 2024-02-23 | 莫纳(武汉)生物科技有限公司 | Quick-insertion type imprinting film clamping device |
WO2021219803A1 (en) * | 2020-05-01 | 2021-11-04 | F. Hoffmann-La Roche Ag | Sample collection tray for multi-well plates |
US20220143620A1 (en) * | 2020-11-10 | 2022-05-12 | Fenwal, Inc. | Retaining table for fluid processing system |
Family Cites Families (31)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4427415A (en) * | 1979-01-05 | 1984-01-24 | Cleveland Patrick H | Manifold vacuum biochemical test method and device |
US4717656A (en) | 1983-12-02 | 1988-01-05 | Vertrik Bioteknik Ab | Device for chemical analyses and use thereof |
US4826759A (en) * | 1984-10-04 | 1989-05-02 | Bio-Metric Systems, Inc. | Field assay for ligands |
US4948442A (en) * | 1985-06-18 | 1990-08-14 | Polyfiltronics, Inc. | Method of making a multiwell test plate |
US4834946A (en) * | 1987-02-05 | 1989-05-30 | Levin Andrew E | Apparatus for blot screening numerous, small volume, antibody solutions |
US4874691A (en) | 1987-10-16 | 1989-10-17 | Quadra Logic Technologies Inc. | Membrane-supported immunoassays |
US5108704A (en) | 1988-09-16 | 1992-04-28 | W. R. Grace & Co.-Conn. | Microfiltration apparatus with radially spaced nozzles |
US5155049A (en) * | 1989-08-22 | 1992-10-13 | Terrapin Technologies, Inc. | Blotting technique for membrane assay |
US5541057A (en) * | 1989-09-18 | 1996-07-30 | Biostar, Inc. | Methods for detection of an analyte |
US5039493A (en) * | 1990-05-04 | 1991-08-13 | The United States Of America As Represented By The Secretary Of The Navy | Positive pressure blotting apparatus with hydropholic filter means |
US5141719A (en) * | 1990-07-18 | 1992-08-25 | Bio-Rad Laboratories, Inc. | Multi-sample filtration plate assembly |
US5264184A (en) | 1991-03-19 | 1993-11-23 | Minnesota Mining And Manufacturing Company | Device and a method for separating liquid samples |
US5149408A (en) * | 1991-04-29 | 1992-09-22 | Brandeis University | Capillary blotting pad for molecular transfer to membranes |
US5368729A (en) * | 1993-07-23 | 1994-11-29 | Whatman, Inc. | Solid phase extraction device |
US6303389B1 (en) * | 1997-06-27 | 2001-10-16 | Immunetics | Rapid flow-through binding assay apparatus and method therefor |
GB2342443A (en) | 1998-10-02 | 2000-04-12 | Abp Diagnostics Limited | Immunoassay device |
US20010001643A1 (en) * | 1998-12-08 | 2001-05-24 | Nigel Simpson | Modular solid phase extraction plate assembly |
US20050255473A1 (en) | 2002-08-02 | 2005-11-17 | Vladimir Knezevic | Methods, devices and kits for multiplex blotting of biological samples from multi-well plates |
KR100675698B1 (en) * | 1999-08-06 | 2007-02-01 | 써모 바이오스타, 인크. | An automated point of care detection system including complete sample processing capabilities |
US6893562B2 (en) | 2000-05-05 | 2005-05-17 | Millipore Corporation | Underdrain for filtration membrane |
US7267804B2 (en) * | 2000-07-07 | 2007-09-11 | Buxbaum Robert E | Membrane reactor for gas extraction |
US6395504B1 (en) * | 2000-09-01 | 2002-05-28 | New Horizons Diagnostics Corp. | Use of phage associated lytic enzymes for the rapid detection of bacterial contaminants |
US20030143124A1 (en) | 2002-01-31 | 2003-07-31 | Roberts Roger Q. | Unidirectional flow control sealing matt |
US20030235520A1 (en) * | 2002-06-21 | 2003-12-25 | Shea Laurence R. | Array assay devices and methods of using the same |
US20040048392A1 (en) | 2002-09-09 | 2004-03-11 | The Gov't Of The U.S.A As Represented By The Secretary Of The Dept.Of Health And Human Services | Container for drying biological samples, method of making such container, and method of using same |
EP1515804B1 (en) * | 2003-06-04 | 2005-10-12 | Millipore Corporation | Universal multiwell filtration plate |
WO2005003346A1 (en) | 2003-06-06 | 2005-01-13 | Applera Corporation | Purification device for ribonucleic acid in large volumes, and method |
US20070111325A1 (en) | 2003-11-28 | 2007-05-17 | Van Beuningen Marinus G J | Methods and devices for compound screening |
US8652421B2 (en) | 2005-11-03 | 2014-02-18 | Emd Millipore Corporation | Immunoassay product and process |
US8557600B2 (en) | 2005-11-03 | 2013-10-15 | Emd Millipore Corporation | Immunoassay product and process |
WO2012154905A1 (en) * | 2011-05-11 | 2012-11-15 | Emd Millipore Corporation | Immunoassay product and process |
-
2006
- 2006-10-18 US US11/582,599 patent/US8652421B2/en active Active
- 2006-10-26 EP EP09153124.4A patent/EP2072135B1/en active Active
- 2006-10-26 ES ES06255513T patent/ES2324834T3/en active Active
- 2006-10-26 ES ES09153124T patent/ES2421401T3/en active Active
- 2006-10-26 AT AT06255513T patent/ATE427492T1/en not_active IP Right Cessation
- 2006-10-26 DE DE602006006002T patent/DE602006006002D1/en active Active
- 2006-10-26 EP EP06255513A patent/EP1783495B1/en active Active
- 2006-10-27 SG SG200607471-0A patent/SG131911A1/en unknown
- 2006-10-27 JP JP2006292152A patent/JP4388945B2/en active Active
-
2010
- 2010-10-25 US US12/911,407 patent/US8460618B2/en active Active
-
2011
- 2011-04-01 US US13/078,290 patent/US8652422B2/en active Active
Also Published As
Publication number | Publication date |
---|---|
JP4388945B2 (en) | 2009-12-24 |
US8652422B2 (en) | 2014-02-18 |
ATE427492T1 (en) | 2009-04-15 |
US20110038757A1 (en) | 2011-02-17 |
ES2324834T3 (en) | 2009-08-17 |
US20110256025A1 (en) | 2011-10-20 |
US8652421B2 (en) | 2014-02-18 |
EP1783495B1 (en) | 2009-04-01 |
DE602006006002D1 (en) | 2009-05-14 |
EP1783495A1 (en) | 2007-05-09 |
JP2007163465A (en) | 2007-06-28 |
US8460618B2 (en) | 2013-06-11 |
EP2072135B1 (en) | 2013-05-29 |
SG131911A1 (en) | 2007-05-28 |
US20070098601A1 (en) | 2007-05-03 |
EP2072135A1 (en) | 2009-06-24 |
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