ES241724A1 - Procedure for the production of pharmacological compounds. (Machine-translation by Google Translate, not legally binding)
- Google Patents
Procedure for the production of pharmacological compounds. (Machine-translation by Google Translate, not legally binding)
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Gruppo Lepetit SpA
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Lepetit SpA
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Procedure for the production of pharmacological compounds, especially for the preparation of a 3,3-bisubstituted-2-acetidinone of the formula: **(See formula)** wherein R and R1 are the same or different and represent a saturated or unsaturated, linear or branched, lower alkyl radical, which may be substituted by halogen, or an aryl, aralkyl, cycloalkyl or cycloalkenyl radical or a substituted aminoalkyl radical, and R2 is hydrogen or a lower alkyl radical, which is characterized by reacting one mole of an aminoester of the formula: **(See formula)** with 2-4 moles of an alkyl magnesium halide in an anhydrous organic solvent, such as benzene, ethyl ether or mixtures thereof, at a temperature between 0º and 5ºC for 1-8 hours. (Machine-translation by Google Translate, not legally binding)
ES0241724A1957-05-031957-05-03Procedure for the production of pharmacological compounds. (Machine-translation by Google Translate, not legally binding)
ExpiredES241724A1
(en)