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Pfizer Italia SRL
Original Assignee
Farmaceutici Italia SpA
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Publication date
Application filed by Farmaceutici Italia SpAfiledCriticalFarmaceutici Italia SpA
Priority to ES0241625ApriorityCriticalpatent/ES241625A1/en
Publication of ES241625A1publicationCriticalpatent/ES241625A1/en
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms
(AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof
(AREA)
Abstract
Process for preparing murexin chloride hydrochloride (beta-4 (5) -imidazyl-acryl-choline), characterized in that cold malonyl monochloride is reacted with choline chloride in an anhydrous medium, an inert solvent, and the reaction mixture is reacted with 4 (5) formyl imidazole in the presence of an aqueous solvent, to which another aqueous solvent has been added, to which has been added another solvent having a high boiling point and is capable of forming an azeotrope with the water, and hydrochloric acid, then the murexin chloride hydrochloride is obtained after removing the water and carbon dioxide formed. (Machine-translation by Google Translate, not legally binding)
ES0241625A1958-04-291958-04-29Procedure for the preparation of murexine (Machine-translation by Google Translate, not legally binding)
ExpiredES241625A1
(en)
A procedure for preparing new therapeutic compounds in the form of free base or acidal salts of non-toxic addiction (Machine-translation by Google Translate, not legally binding)
Procedure for obtaining a compound of addition of hexametilentetramine with p-aminobencenosulfonamide (Machine-translation by Google Translate, not legally binding)
Procedure for the obtaining of therapeutically active cyanatic acid hydrazide derivatives (Machine-translation by Google Translate, not legally binding)
Procedure for the manufacture of the indofenol-tiosulfºnic acids of the carbazol and N-alkil carbazol (Machine-translation by Google Translate, not legally binding)