ES241381A1 - Procedure for the synthesis of 5-hydroxy-7-methyl-s-triazol (4,3-c) -pirimidines. (Machine-translation by Google Translate, not legally binding)
- Google Patents
Procedure for the synthesis of 5-hydroxy-7-methyl-s-triazol (4,3-c) -pirimidines. (Machine-translation by Google Translate, not legally binding)
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Pfizer Italia SRL
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Farmaceutici Italia SpA
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Low-Molecular Organic Synthesis Reactions Using Catalysts
(AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof
(AREA)
Abstract
Process for preparing 5-hydroxy-7-methyl-s-triazole (43-c) -pyrimidines represented by the general structural formula in which r is hydrogenalkylcarboxyalkylocarboxyarylsh characterized in that 2-hydroxy-4 is reacted -methyl-6-hydrazino-pyrimidines having the formula ** with a carboxylic acid or an acid chloride with an acid anhydride in the presence or absence of a base at a temperature ranging between 20 and 120ºC and the 2-hydroxy-4-methyl-6-acyl-hydrazino-pyramidin thus formed as cyclized intermediates by heating it at temperatures of 200 to 300ºC in the absence of solvent or in the presence of pyridine at the boiling point. (Machine-translation by Google Translate, not legally binding)
ES0241381A1958-03-281958-03-28Procedure for the synthesis of 5-hydroxy-7-methyl-s-triazol (4,3-c) -pirimidines. (Machine-translation by Google Translate, not legally binding)
ExpiredES241381A1
(en)
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