Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Wyeth Holdings LLC
Original Assignee
American Cyanamid Co
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Filing date
Publication date
Priority claimed from US619947Aexternal-prioritypatent/US2923667A/en
Application filed by American Cyanamid CofiledCriticalAmerican Cyanamid Co
Publication of ES238208A1publicationCriticalpatent/ES238208A1/en
A method of producing tetracycline characterized by the aerobic fermentation of an aqueous fermentation medium containing chloride ions with a microorganism of the genus Streptomyces and addition to said medium of a chlorination inhibitor of the formula: (see formula) wherein X is hydrogen or a lower alkyl radical, Y is hydrogen, phenyl, amino, lower alkyl, or the group (see formula) or (see formula), where R is phenyl or lower alkyl phenyl and Z is a term of the group consisting of S (lower alkyl), SCH2, SCH2COOH, (see formula), ** (See formula) ** whereby the formation of chlorotetracycline is inhibited and considerable amounts of tetracycline are produced. (Machine-translation by Google Translate, not legally binding)
ES0238208A1956-11-021957-10-22A procedure to produce tetracycline (Machine-translation by Google Translate, not legally binding)
ExpiredES238208A1
(en)