ES2351598T3 - Proteína frpb mutante y procedimiento de replegamiento. - Google Patents

Proteína frpb mutante y procedimiento de replegamiento. Download PDF

Info

Publication number
ES2351598T3
ES2351598T3 ES03779785T ES03779785T ES2351598T3 ES 2351598 T3 ES2351598 T3 ES 2351598T3 ES 03779785 T ES03779785 T ES 03779785T ES 03779785 T ES03779785 T ES 03779785T ES 2351598 T3 ES2351598 T3 ES 2351598T3
Authority
ES
Spain
Prior art keywords
protein
frpb
neisseria
loop
amino acids
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES03779785T
Other languages
English (en)
Spanish (es)
Inventor
Ralph Biemans
Jan Tommassen
Carine Goraj
Christiane Feron
Vincent Weynants
Philippe Denoel
Jeroen Kortekaas
Jan Poolman
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
TECHNOLOGY FOUNDATION (STICHTING VOOR DE TECHNISCHE WETENSCHAPPEN)
Technology Foundation Stichting Voor De Tech Wetenschappen
GlaxoSmithKline Biologicals SA
Universiteit Utrecht
Original Assignee
TECHNOLOGY FOUNDATION (STICHTING VOOR DE TECHNISCHE WETENSCHAPPEN)
Technology Foundation Stichting Voor De Tech Wetenschappen
GlaxoSmithKline Biologicals SA
Rijksuniversiteit Utrecht
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by TECHNOLOGY FOUNDATION (STICHTING VOOR DE TECHNISCHE WETENSCHAPPEN), Technology Foundation Stichting Voor De Tech Wetenschappen, GlaxoSmithKline Biologicals SA, Rijksuniversiteit Utrecht filed Critical TECHNOLOGY FOUNDATION (STICHTING VOOR DE TECHNISCHE WETENSCHAPPEN)
Application granted granted Critical
Publication of ES2351598T3 publication Critical patent/ES2351598T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/02Bacterial antigens
    • A61K39/102Pasteurellales, e.g. Actinobacillus, Pasteurella; Haemophilus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/02Bacterial antigens
    • A61K39/095Neisseria
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/02Bacterial antigens
    • A61K39/104Pseudomonadales, e.g. Pseudomonas
    • A61K39/1045Moraxella
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/22Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Neisseriaceae (F)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55505Inorganic adjuvants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511Organic adjuvants
    • A61K2039/55516Proteins; Peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511Organic adjuvants
    • A61K2039/55572Lipopolysaccharides; Lipid A; Monophosphoryl lipid A
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511Organic adjuvants
    • A61K2039/55577Saponins; Quil A; QS21; ISCOMS

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
ES03779785T 2002-08-30 2003-08-28 Proteína frpb mutante y procedimiento de replegamiento. Expired - Lifetime ES2351598T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB0220199 2002-08-30
GBGB0220199.4A GB0220199D0 (en) 2002-08-30 2002-08-30 Mutant protein and refolding method

Publications (1)

Publication Number Publication Date
ES2351598T3 true ES2351598T3 (es) 2011-02-08

Family

ID=9943242

Family Applications (1)

Application Number Title Priority Date Filing Date
ES03779785T Expired - Lifetime ES2351598T3 (es) 2002-08-30 2003-08-28 Proteína frpb mutante y procedimiento de replegamiento.

Country Status (10)

Country Link
US (1) US20060141563A1 (enExample)
EP (1) EP1572729B1 (enExample)
JP (1) JP2006516183A (enExample)
AT (1) ATE481983T1 (enExample)
AU (1) AU2003287945A1 (enExample)
CA (1) CA2495086A1 (enExample)
DE (1) DE60334316D1 (enExample)
ES (1) ES2351598T3 (enExample)
GB (1) GB0220199D0 (enExample)
WO (1) WO2004020463A2 (enExample)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2414667A (en) * 2004-06-03 2005-12-07 Isis Innovation Vaccine compositions of N. meningitidis PorA and FetA antigens
HUE047211T2 (hu) 2005-06-27 2020-04-28 Glaxosmithkline Biologicals Sa Konjugált natív N. meningitidis kapszuláris poliszacharidokat tartalmazó vakcinakészítmény
CA2654706A1 (en) * 2006-06-12 2007-12-21 Nathalie Devos Neisseria meningitidis lipooligosaccharide vaccine
JP5568017B2 (ja) * 2008-12-25 2014-08-06 一般財団法人化学及血清療法研究所 組換え鶏伝染性コリーザワクチン及びその製造方法
CA2810971C (en) * 2010-09-10 2020-11-03 Novartis Ag Developments in meningococcal outer membrane vesicles
CA2811699C (en) * 2010-09-28 2019-07-02 Abera Bioscience Ab Fusion protein for secretory protein expression

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6265567B1 (en) * 1995-04-07 2001-07-24 University Of North Carolina At Chapel Hill Isolated FrpB nucleic acid molecule
US6084076A (en) * 1995-12-21 2000-07-04 Ajinomoto Co., Inc. Method of refolding human activin A
AU2818101A (en) * 2000-01-25 2001-08-07 University Of Queensland, The proteins comprising conserved regions of neisseria meningitidis surface antigen NhhA

Also Published As

Publication number Publication date
EP1572729A2 (en) 2005-09-14
US20060141563A1 (en) 2006-06-29
AU2003287945A8 (en) 2004-03-19
JP2006516183A (ja) 2006-06-29
CA2495086A1 (en) 2004-03-11
DE60334316D1 (de) 2010-11-04
WO2004020463A2 (en) 2004-03-11
AU2003287945A1 (en) 2004-03-19
ATE481983T1 (de) 2010-10-15
GB0220199D0 (en) 2002-10-09
EP1572729B1 (en) 2010-09-22
WO2004020463A3 (en) 2005-08-18

Similar Documents

Publication Publication Date Title
ES2408251T3 (es) Composiciones de vacuna contra Neisseria que comprenden una combinación de antígenos
US8163295B2 (en) Outer membrane vesicles and uses thereof
US20170209562A1 (en) Immunogenic composition
US20100291137A1 (en) Method for refolding neisserial nspa protein
ES2351598T3 (es) Proteína frpb mutante y procedimiento de replegamiento.
RU2359696C2 (ru) Вакцинная композиция, содержащая трансферрин-связывающий белок и hsf из грамотрицательных бактерий
HK1077014B (en) Neisserial vaccine compositions comprising a combination of antigens
HK1144909A (en) Neisseria vaccine composition