ATE481983T1 - Frpb proteinmutante und verfahren zur erneuten faltung - Google Patents

Frpb proteinmutante und verfahren zur erneuten faltung

Info

Publication number
ATE481983T1
ATE481983T1 AT03779785T AT03779785T ATE481983T1 AT E481983 T1 ATE481983 T1 AT E481983T1 AT 03779785 T AT03779785 T AT 03779785T AT 03779785 T AT03779785 T AT 03779785T AT E481983 T1 ATE481983 T1 AT E481983T1
Authority
AT
Austria
Prior art keywords
frpb protein
protein mutant
refolding method
frpb
refolding
Prior art date
Application number
AT03779785T
Other languages
German (de)
English (en)
Inventor
Ralph Biemans
Philippe Denoel
Christiane Feron
Carine Goraj
Jeroen Kortekaas
Jan Poolman
Jan Tommassen
Vincent Weynants
Original Assignee
Glaxosmithkline Biolog Sa
Univ Utrecht
Technology Foundation Stichtin
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxosmithkline Biolog Sa, Univ Utrecht, Technology Foundation Stichtin filed Critical Glaxosmithkline Biolog Sa
Application granted granted Critical
Publication of ATE481983T1 publication Critical patent/ATE481983T1/de

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/02Bacterial antigens
    • A61K39/102Pasteurellales, e.g. Actinobacillus, Pasteurella; Haemophilus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/02Bacterial antigens
    • A61K39/095Neisseria
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/02Bacterial antigens
    • A61K39/104Pseudomonadales, e.g. Pseudomonas
    • A61K39/1045Moraxella
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/22Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Neisseriaceae (F)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55505Inorganic adjuvants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511Organic adjuvants
    • A61K2039/55516Proteins; Peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511Organic adjuvants
    • A61K2039/55572Lipopolysaccharides; Lipid A; Monophosphoryl lipid A
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511Organic adjuvants
    • A61K2039/55577Saponins; Quil A; QS21; ISCOMS

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
AT03779785T 2002-08-30 2003-08-28 Frpb proteinmutante und verfahren zur erneuten faltung ATE481983T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0220199.4A GB0220199D0 (en) 2002-08-30 2002-08-30 Mutant protein and refolding method
PCT/EP2003/009634 WO2004020463A2 (en) 2002-08-30 2003-08-28 Mutant protein and refolding method

Publications (1)

Publication Number Publication Date
ATE481983T1 true ATE481983T1 (de) 2010-10-15

Family

ID=9943242

Family Applications (1)

Application Number Title Priority Date Filing Date
AT03779785T ATE481983T1 (de) 2002-08-30 2003-08-28 Frpb proteinmutante und verfahren zur erneuten faltung

Country Status (10)

Country Link
US (1) US20060141563A1 (enExample)
EP (1) EP1572729B1 (enExample)
JP (1) JP2006516183A (enExample)
AT (1) ATE481983T1 (enExample)
AU (1) AU2003287945A1 (enExample)
CA (1) CA2495086A1 (enExample)
DE (1) DE60334316D1 (enExample)
ES (1) ES2351598T3 (enExample)
GB (1) GB0220199D0 (enExample)
WO (1) WO2004020463A2 (enExample)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2414667A (en) * 2004-06-03 2005-12-07 Isis Innovation Vaccine compositions of N. meningitidis PorA and FetA antigens
HUE047211T2 (hu) 2005-06-27 2020-04-28 Glaxosmithkline Biologicals Sa Konjugált natív N. meningitidis kapszuláris poliszacharidokat tartalmazó vakcinakészítmény
CA2654706A1 (en) * 2006-06-12 2007-12-21 Nathalie Devos Neisseria meningitidis lipooligosaccharide vaccine
JP5568017B2 (ja) * 2008-12-25 2014-08-06 一般財団法人化学及血清療法研究所 組換え鶏伝染性コリーザワクチン及びその製造方法
CA2810971C (en) * 2010-09-10 2020-11-03 Novartis Ag Developments in meningococcal outer membrane vesicles
CA2811699C (en) * 2010-09-28 2019-07-02 Abera Bioscience Ab Fusion protein for secretory protein expression

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6265567B1 (en) * 1995-04-07 2001-07-24 University Of North Carolina At Chapel Hill Isolated FrpB nucleic acid molecule
US6084076A (en) * 1995-12-21 2000-07-04 Ajinomoto Co., Inc. Method of refolding human activin A
AU2818101A (en) * 2000-01-25 2001-08-07 University Of Queensland, The proteins comprising conserved regions of neisseria meningitidis surface antigen NhhA

Also Published As

Publication number Publication date
EP1572729A2 (en) 2005-09-14
US20060141563A1 (en) 2006-06-29
AU2003287945A8 (en) 2004-03-19
JP2006516183A (ja) 2006-06-29
CA2495086A1 (en) 2004-03-11
DE60334316D1 (de) 2010-11-04
WO2004020463A2 (en) 2004-03-11
ES2351598T3 (es) 2011-02-08
AU2003287945A1 (en) 2004-03-19
GB0220199D0 (en) 2002-10-09
EP1572729B1 (en) 2010-09-22
WO2004020463A3 (en) 2005-08-18

Similar Documents

Publication Publication Date Title
ATE450619T1 (de) Defructosylierungsverfahren
EP1623227A4 (en) PROTEINS, SENSORS AND METHODS FOR CHARACTERIZING SUBSTANCES TO BE ANALYZED USING THESE PROTEINS AND THESE SENSORS
DE60309087D1 (de) System und Methode zur Reglung von optischen Verstärkern
SG149000A1 (en) Gag binding proteins
DK1668001T3 (da) Substituerede heteroarylbenzofuransyrer
DE60207053D1 (de) Rekombinante gelatineartige proteine zur verwendung als plasmaexpander
ATE484201T1 (de) Verwendung von beta-cryptoxanthin
DE69933551D1 (de) Menschliche protease und verwendung davon für pharmazeutischen anwendungen und zur reduktion der allergisierenden wirkung von nicht-menschlichen proteinen
ATE481983T1 (de) Frpb proteinmutante und verfahren zur erneuten faltung
DE60335497D1 (de) Ergillus-phytasen
ATE323763T1 (de) Dna & protein bindende miniatur proteine
DE60301283D1 (de) Verfahren zur Bestimmung von Biopolymeren
DE60325194D1 (de) Methoden zur verwendung von lamellaren körpern für therapeutische zwecke
NO20050599L (no) Fremgangsmate for a anrike og spore patologisk modifiserte prion-proteiner (PRPsc)
ATE355641T1 (de) Techniken zur vorspannung von lasern
ATE370964T1 (de) Isoliertes fluoreszierendes protein aus clytia gregaria cgfp, sowie dessen verwendung
DE50309626D1 (de) Verfahren zur vorhersage der expressionseffizienz in zellfreien expressionssystemen
ATE269905T1 (de) Verfahren zur herstellung von proteinen in wirtszellen unter verwendung von chaperoninen
DE60215206D1 (de) Enzymatisches verfahren zur enantiomeren trennung von aminosäuren
ATE437650T1 (de) Tyrosinasemutante und verfahren zur verwendung davon
DE60317620D1 (de) Methode zur Bestimmung von UDP-GlcNac
DE602006010990D1 (de) Verfahren zur dipeptidherstellung
ATE320499T1 (de) Optimierte proteinsynthese
BRPI0408023A (pt) métodos para previnir gliconoilação de proteìnas
FI20020332A0 (fi) Valmiste ja menetelmä painon pudottamiseksi

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties