ES2350330T3 - Tratamiento de la hiperactividad del músculo liso con (r)-oxibutinina y (r)-desetiloxibutinina. - Google Patents
Tratamiento de la hiperactividad del músculo liso con (r)-oxibutinina y (r)-desetiloxibutinina. Download PDFInfo
- Publication number
- ES2350330T3 ES2350330T3 ES00941235T ES00941235T ES2350330T3 ES 2350330 T3 ES2350330 T3 ES 2350330T3 ES 00941235 T ES00941235 T ES 00941235T ES 00941235 T ES00941235 T ES 00941235T ES 2350330 T3 ES2350330 T3 ES 2350330T3
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- Spain
- Prior art keywords
- butynyl
- cyclohexylphenylglycolate
- pharmaceutically acceptable
- salt
- solvate
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
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Applications Claiming Priority (1)
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| PCT/US2000/015515 WO2001093683A1 (en) | 2000-06-07 | 2000-06-07 | Treating smooth muscle hyperactivity with (r)-oxybutynin and (r)- desethyloxybutynin |
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| CN (3) | CN1454054A (https=) |
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| ES (1) | ES2350330T3 (https=) |
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| JP2005516992A (ja) * | 2001-12-21 | 2005-06-09 | ブリッジ ファーマ、インコーポレイテッド | オキシブチニンの非心律動異常惹起性代謝物 |
| EP1424079A1 (en) * | 2002-11-27 | 2004-06-02 | Boehringer Ingelheim International GmbH | Combination of a beta-3-receptor agonist and of a reuptake inhibitor of serotonin and/or norepinephrine |
| ATE361101T1 (de) * | 2004-08-24 | 2007-05-15 | Nutricia Nv | Nahrungszusammensetzung die unverdauliche oligosaccharide enthält |
| US8920392B2 (en) | 2009-05-05 | 2014-12-30 | Watson Laboratories, Inc. | Method for treating overactive bladders and a device for storage and administration of topical oxybutynin compositions |
| EP2680859B1 (en) | 2011-03-02 | 2022-04-27 | Jerome Schentag | Compositions, methods of treatment and diagnostics for treatment of hepatic steatosis alone or in combination with a hepatitis c virus infection |
| US10532045B2 (en) | 2013-12-18 | 2020-01-14 | Signpath Pharma, Inc. | Liposomal mitigation of drug-induced inhibition of the cardiac IKr channel |
| US10449193B2 (en) | 2011-06-03 | 2019-10-22 | Signpath Pharma Inc. | Protective effect of DMPC, DMPG, DMPC/DMPG, lysoPG and lysoPC against drugs that cause channelopathies |
| US8753674B2 (en) | 2011-06-03 | 2014-06-17 | Signpath Pharma Inc. | Liposomal mitigation of drug-induced long QT syndrome and potassium delayed-rectifier current |
| US10238602B2 (en) | 2011-06-03 | 2019-03-26 | Signpath Pharma, Inc. | Protective effect of DMPC, DMPG, DMPC/DMPG, LysoPG and LysoPC against drugs that cause channelopathies |
| US10349884B2 (en) | 2011-06-03 | 2019-07-16 | Sighpath Pharma Inc. | Liposomal mitigation of drug-induced inhibition of the cardiac ikr channel |
| US12004868B2 (en) | 2011-06-03 | 2024-06-11 | Signpath Pharma Inc. | Liposomal mitigation of drug-induced inhibition of the cardiac IKr channel |
| US10117881B2 (en) | 2011-06-03 | 2018-11-06 | Signpath Pharma, Inc. | Protective effect of DMPC, DMPG, DMPC/DMPG, LYSOPG and LYSOPC against drugs that cause channelopathies |
| US20140135392A1 (en) * | 2012-11-13 | 2014-05-15 | NeuRx Pharmaceuticals LLC | Methods for the treatment of sialorrhea |
| US20160151321A1 (en) | 2012-11-13 | 2016-06-02 | Dinesh C. Patel | Methods for the treatment of sialorrhea |
| CN103169660B (zh) * | 2013-04-15 | 2015-04-08 | 石正国 | 一种制备高包封率的利巴韦林脂质体口服乳 |
| AU2015269699B2 (en) | 2014-06-03 | 2020-08-13 | Avanti Polar Lipids, Inc. | Protective effect of DMPC, DMPG, DMPC/DMPG, EGPG, LysoPG and LysoPC against drugs that cause channelopathies |
| AU2017257496B2 (en) | 2016-04-27 | 2020-05-07 | Signpath Pharma, Inc. | Prevention of drug-induced atrio-ventricular block |
| JP7776442B2 (ja) * | 2020-05-05 | 2025-11-26 | アプニメッド，インコーポレイテッド（デラウェア） | （ｒ）－オキシブチニン塩酸塩の多形形態 |
| TW202207952A (zh) * | 2020-07-03 | 2022-03-01 | 愛爾蘭商普候克斯根有限公司 | 病毒感染 |
| CN117396460A (zh) * | 2021-05-04 | 2024-01-12 | 爱普宁公司(特拉华) | (r)-奥昔布宁d-苹果酸盐的固体形式 |
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| US4008269A (en) * | 1970-05-05 | 1977-02-15 | William H. Rorer, Inc. | Phenylacetic acids |
| IT1231237B (it) * | 1987-09-21 | 1991-11-26 | Angeli Inst Spa | Derivati eterociclici |
| US5677346A (en) * | 1995-01-31 | 1997-10-14 | Sepracor, Inc. | Treating urinary incontinence using (S)-desethyloxybutynin |
| US5973182A (en) * | 1998-10-22 | 1999-10-26 | Sepracor Inc. | Carbonate Intermediates useful in the preparation of optically active cyclohexylphenylglycolate esters |
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- 2000-06-07 AU AU2000255966A patent/AU2000255966B2/en not_active Expired
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- 2000-06-07 WO PCT/US2000/015515 patent/WO2001093683A1/en not_active Ceased
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Also Published As
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|---|---|
| EP1286591A4 (en) | 2007-04-04 |
| JP5684964B2 (ja) | 2015-03-18 |
| CN1454054A (zh) | 2003-11-05 |
| AU2000255966B2 (en) | 2005-03-24 |
| JP2003535110A (ja) | 2003-11-25 |
| WO2001093683A1 (en) | 2001-12-13 |
| AU2000255966A1 (en) | 2002-03-07 |
| CA2378754A1 (en) | 2001-12-13 |
| EP1286591A1 (en) | 2003-03-05 |
| DE60045082D1 (de) | 2010-11-18 |
| CN1451388A (zh) | 2003-10-29 |
| EP1286591B1 (en) | 2010-10-06 |
| ATE483459T1 (de) | 2010-10-15 |
| CN101108176A (zh) | 2008-01-23 |
| AU5596600A (en) | 2001-12-17 |
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