ES2334084B1 - Marcadores geneticos para el pronostico de la esclerosis multiple. - Google Patents
Marcadores geneticos para el pronostico de la esclerosis multiple. Download PDFInfo
- Publication number
- ES2334084B1 ES2334084B1 ES200703415A ES200703415A ES2334084B1 ES 2334084 B1 ES2334084 B1 ES 2334084B1 ES 200703415 A ES200703415 A ES 200703415A ES 200703415 A ES200703415 A ES 200703415A ES 2334084 B1 ES2334084 B1 ES 2334084B1
- Authority
- ES
- Spain
- Prior art keywords
- multiple sclerosis
- genes
- expression
- patient
- subjects suffering
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn - After Issue
Links
- 201000006417 multiple sclerosis Diseases 0.000 title abstract 5
- 230000002068 genetic effect Effects 0.000 title 1
- 108090000623 proteins and genes Proteins 0.000 abstract 5
- 238000004393 prognosis Methods 0.000 abstract 3
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
- G16H50/00—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
- G16H50/70—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for mining of medical data, e.g. analysing previous cases of other patients
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/118—Prognosis of disease development
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A90/00—Technologies having an indirect contribution to adaptation to climate change
- Y02A90/10—Information and communication technologies [ICT] supporting adaptation to climate change, e.g. for weather forecasting or climate simulation
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Analytical Chemistry (AREA)
- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
- Pathology (AREA)
- Public Health (AREA)
- Medical Informatics (AREA)
- Data Mining & Analysis (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Physics & Mathematics (AREA)
- Molecular Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Microbiology (AREA)
- Databases & Information Systems (AREA)
- Biomedical Technology (AREA)
- Epidemiology (AREA)
- Primary Health Care (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Priority Applications (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ES200703415A ES2334084B1 (es) | 2007-12-21 | 2007-12-21 | Marcadores geneticos para el pronostico de la esclerosis multiple. |
US12/809,726 US20130184167A1 (en) | 2007-12-21 | 2008-12-18 | Genetic markers for the prognosis of multiple sclerosis |
PCT/ES2008/000785 WO2009080849A2 (es) | 2007-12-21 | 2008-12-18 | Marcadores genéticos para el pronóstico de la esclerosis múltiple |
EP08865077A EP2233586A4 (en) | 2007-12-21 | 2008-12-18 | GENETIC MARKERS FOR THE PROGNOSIS OF MULTIPLE SCLEROSIS |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ES200703415A ES2334084B1 (es) | 2007-12-21 | 2007-12-21 | Marcadores geneticos para el pronostico de la esclerosis multiple. |
Publications (2)
Publication Number | Publication Date |
---|---|
ES2334084A1 ES2334084A1 (es) | 2010-03-04 |
ES2334084B1 true ES2334084B1 (es) | 2011-01-24 |
Family
ID=40801620
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES200703415A Withdrawn - After Issue ES2334084B1 (es) | 2007-12-21 | 2007-12-21 | Marcadores geneticos para el pronostico de la esclerosis multiple. |
Country Status (4)
Country | Link |
---|---|
US (1) | US20130184167A1 (es) |
EP (1) | EP2233586A4 (es) |
ES (1) | ES2334084B1 (es) |
WO (1) | WO2009080849A2 (es) |
Family Cites Families (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ATE340870T1 (de) | 1998-04-03 | 2006-10-15 | Compound Therapeutics Inc | Adressierbare protein arrays |
WO1999054463A2 (en) * | 1998-04-21 | 1999-10-28 | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. | Human k+ ion channel and therapeutic applications thereof |
US20060115826A1 (en) | 1999-06-28 | 2006-06-01 | Michael Bevilacqua | Gene expression profiling for identification monitoring and treatment of multiple sclerosis |
GB9928787D0 (en) | 1999-12-03 | 2000-02-02 | Medical Res Council | Direct screening method |
WO2002079218A1 (en) | 2001-03-30 | 2002-10-10 | Wyeth | Methods for diagnosing and treating multiple sclerosis and compositions thereof |
ATE485515T1 (de) | 2001-06-22 | 2010-11-15 | Burkhard Jansen | Verfahren zur diagnose einer person mit multipler sklerose |
WO2003023056A2 (en) | 2001-09-12 | 2003-03-20 | F. Hoffmann-La Roche Ag | Specific markers for multiple sclerosis |
WO2003081201A2 (en) | 2002-03-21 | 2003-10-02 | Yissum Research Development Company Of The Hebrew University Of Jerusalem | Peripheral blood cell markers useful for diagnosing multiple sclerosis and methods and kits utilizing same |
US20040018522A1 (en) | 2002-05-09 | 2004-01-29 | Brigham And Women's Hospital, Inc. | Identification of dysregulated genes in patients with multiple sclerosis |
US20060058225A1 (en) * | 2002-05-31 | 2006-03-16 | Mcgill University | Used of inhibitors of phospholipase a2 for the treatment, prevention or diagnosis of neural inflammatory or demyelinating disease |
JP3856734B2 (ja) * | 2002-06-28 | 2006-12-13 | 株式会社日立製作所 | 多発性硬化症に対するインターフェロン・ベータ薬物治療の有効性予測方法 |
US20040091915A1 (en) | 2002-07-30 | 2004-05-13 | David Comings | Methods for predicting survival rate in patients having multiple sclerosis |
US20050064483A1 (en) | 2003-08-28 | 2005-03-24 | Baylor College Of Medicine | Gene expression profiling technology for treatment evaluation of multiple sclerosis |
US20090011407A1 (en) | 2003-11-26 | 2009-01-08 | The Ohio State University Research Foundation | Polymorphic Cd24 Genotypes that are Predictive of Multiple Sclerosis Risk and Progression |
JP2005160440A (ja) | 2003-12-05 | 2005-06-23 | Hitachi Ltd | 多発性硬化症に関連する遺伝子の発現測定方法、多発性硬化症関連遺伝子の発現を測定するためのチップ、多発性硬化症の罹患を判断するための遺伝子群、多発性硬化症の評価方法 |
EP1550873A1 (en) * | 2003-12-30 | 2005-07-06 | Progenika Biopharma, S.A. | Methods for the in vitro diagnosis and prognosis of demyelinating diseases and for the development of drugs against demyelinating diseases |
EP2062981B1 (en) * | 2005-06-16 | 2013-09-25 | Life Technologies Corporation | Gene expression profiling for identification and monitoring of multiple sclerosis |
-
2007
- 2007-12-21 ES ES200703415A patent/ES2334084B1/es not_active Withdrawn - After Issue
-
2008
- 2008-12-18 US US12/809,726 patent/US20130184167A1/en not_active Abandoned
- 2008-12-18 WO PCT/ES2008/000785 patent/WO2009080849A2/es active Application Filing
- 2008-12-18 EP EP08865077A patent/EP2233586A4/en not_active Withdrawn
Also Published As
Publication number | Publication date |
---|---|
WO2009080849A3 (es) | 2009-09-17 |
EP2233586A2 (en) | 2010-09-29 |
EP2233586A4 (en) | 2011-02-09 |
US20130184167A1 (en) | 2013-07-18 |
ES2334084A1 (es) | 2010-03-04 |
WO2009080849A2 (es) | 2009-07-02 |
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Legal Events
Date | Code | Title | Description |
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EC2A | Search report published |
Date of ref document: 20100304 Kind code of ref document: A1 |
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