ES2229829A1 - High pressure microfluidic valve, has electrostatic actuator provided between pressure control units, chamber connected with pressure control units through inlet, and intermediate wafer and lower wafer formed with chamber - Google Patents

High pressure microfluidic valve, has electrostatic actuator provided between pressure control units, chamber connected with pressure control units through inlet, and intermediate wafer and lower wafer formed with chamber

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Publication number
ES2229829A1
ES2229829A1 ES200102361A ES200102361A ES2229829A1 ES 2229829 A1 ES2229829 A1 ES 2229829A1 ES 200102361 A ES200102361 A ES 200102361A ES 200102361 A ES200102361 A ES 200102361A ES 2229829 A1 ES2229829 A1 ES 2229829A1
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Spain
Prior art keywords
wafer
valve
chamber
control units
high pressure
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
ES200102361A
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Spanish (es)
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ES2229829B1 (en
Inventor
Jose Manuel Quero Reboul
Antonio Luque Esteban
Leopoldo Garcia Franquelo
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Universidad de Sevilla
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Universidad de Sevilla
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Priority to ES200102361A priority Critical patent/ES2229829B1/en
Publication of ES2229829A1 publication Critical patent/ES2229829A1/en
Application granted granted Critical
Publication of ES2229829B1 publication Critical patent/ES2229829B1/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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Classifications

    • FMECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F16ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
    • F16KVALVES; TAPS; COCKS; ACTUATING-FLOATS; DEVICES FOR VENTING OR AERATING
    • F16K7/00Diaphragm valves or cut-off apparatus, e.g. with a member deformed, but not moved bodily, to close the passage ; Pinch valves
    • F16K7/12Diaphragm valves or cut-off apparatus, e.g. with a member deformed, but not moved bodily, to close the passage ; Pinch valves with flat, dished, or bowl-shaped diaphragm
    • F16K7/14Diaphragm valves or cut-off apparatus, e.g. with a member deformed, but not moved bodily, to close the passage ; Pinch valves with flat, dished, or bowl-shaped diaphragm arranged to be deformed against a flat seat
    • F16K7/17Diaphragm valves or cut-off apparatus, e.g. with a member deformed, but not moved bodily, to close the passage ; Pinch valves with flat, dished, or bowl-shaped diaphragm arranged to be deformed against a flat seat the diaphragm being actuated by fluid pressure
    • FMECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F16ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
    • F16KVALVES; TAPS; COCKS; ACTUATING-FLOATS; DEVICES FOR VENTING OR AERATING
    • F16K31/00Actuating devices; Operating means; Releasing devices
    • F16K31/12Actuating devices; Operating means; Releasing devices actuated by fluid
    • F16K31/126Actuating devices; Operating means; Releasing devices actuated by fluid the fluid acting on a diaphragm, bellows, or the like
    • F16K31/1266Actuating devices; Operating means; Releasing devices actuated by fluid the fluid acting on a diaphragm, bellows, or the like one side of the diaphragm being acted upon by the circulating fluid
    • FMECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F16ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
    • F16KVALVES; TAPS; COCKS; ACTUATING-FLOATS; DEVICES FOR VENTING OR AERATING
    • F16K47/00Means in valves for absorbing fluid energy
    • F16K47/04Means in valves for absorbing fluid energy for decreasing pressure or noise level, the throttle being incorporated in the closure member

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  • Engineering & Computer Science (AREA)
  • General Engineering & Computer Science (AREA)
  • Mechanical Engineering (AREA)
  • Physics & Mathematics (AREA)
  • Fluid Mechanics (AREA)
  • Electrically Driven Valve-Operating Means (AREA)
  • Fluid-Driven Valves (AREA)

Abstract

The valve has a lower wafer (1), an intermediate wafer (2) and a top wafer (3) formed with a deep recess (4) that is protruded into a deformable stopper membrane (5). A fluid inlet hole (10) and a fluid outlet hole (11) are formed in the top wafer. The intermediate wafer and the lower wafer are formed with a chamber (6) that is connected with pressure control units through an inlet (7). An electrostatic actuator (9) is provided between the pressure control units.

Description

Válvula microfluídica para alta presión.Microfluidic valve for high pressure.

Objeto de la invenciónObject of the invention

La presente invención se refiere a una válvula que resulta especialmente idónea para el control y la regulación del flujo de un líquido a escala microscópica.The present invention relates to a valve which is especially suitable for control and regulation of the flow of a liquid on a microscopic scale.

De forma más concreta la válvula que se preconiza ha sido especialmente concebida para el control de líquidos a alta presión y está estructurada en orden a conseguir una gran facilidad de maniobra en la apertura y cierre de la misma, con una óptima funcionalidad y un consumo energético mínimo.More specifically the valve that is recommended It has been specially designed to control liquids at high pressure and is structured in order to achieve great ease of maneuver in the opening and closing of the same, with an optimal functionality and minimal energy consumption.

La válvula resulta de especial aplicación en dispositivos microfluídicos tales como chips biológicos, reactores químicos, análisis genético, etc.The valve is of special application in microfluidic devices such as biological chips, reactors chemicals, genetic analysis, etc.

Antecedentes de la invenciónBackground of the invention

En el ámbito de la aplicación práctica anteriormente citado existen válvulas microfluídicas con diferentes tipos de actuación y con geometrías asimismo diferentes. En este sentido existen válvulas con actuación magnética, electrostática, neumática, térmica o de otros tipos, e incluso válvulas con actuaciones mixtas.In the field of practical application previously mentioned there are microfluidic valves with different types of action and with different geometries. In this sense there are valves with magnetic, electrostatic actuation, pneumatic, thermal or other types, and even valves with mixed performances.

Estas microválvulas o válvulas microfluídicas resultan funcionalmente correctas cuando las diferencias de presión entre la entrada y la salida de fluido son relativamente bajas, pero cuando tales diferencias son de varias atmósferas no son capaces de vencerlas y, en la mayoría de los casos, la actuación de la válvula es agresiva con el flujo de trabajo, especialmente cuando los medios de actuación son de tipo eléctrico.These micro valves or microfluidic valves they are functionally correct when the pressure differences between the fluid inlet and outlet are relatively low, but when such differences are from various atmospheres they are not able to overcome them and, in most cases, the performance of the valve is aggressive with the workflow, especially when the means of action are electric.

Descripción de la invenciónDescription of the invention

La válvula microfluídica que la invención propone, que puede situarse en el ámbito de las válvulas con medios de actuación combinados, resuelve de forma plenamente satisfactoria la problemática anteriormente expuesta, permitiendo un accionamiento valvular correcto con altas presiones y sin que la válvula resulte agresiva con el fluido de trabajo.The microfluidic valve that the invention proposes, which can be placed in the field of valves with means of combined action, resolves fully satisfactorily the problem described above, allowing a correct valve operation with high pressures and without the valve is aggressive with the working fluid.

Para ello y de forma más concreta la válvula que se preconiza está estructurada mediante tres obleas, que pueden estar obtenidas en diferentes materiales, como se verá más adelante, y que son mecanizadas o atacadas con diferentes reactivos para conferirles la forma apropiada, acorde con su filosofía funcional.For this and more specifically the valve that it is recommended it is structured by three wafers, which can be obtained in different materials, as you will see more ahead, and that are mechanized or attacked with different reagents to give them the appropriate form, in accordance with their philosophy functional.

Específicamente la oblea inferior cumple la función de soporte del conjunto, la intermedia forma el cuerpo de válvula, incluyendo el obturador o dispositivo móvil de actuación, y la superior contiene los orificios de entrada y salida del fluido, de manera que el caudal del paso del fluido depende de la posición de la membrana u obturador definido en la oblea intermedia.Specifically the bottom wafer meets the support function of the set, the intermediate forms the body of valve, including the shutter or mobile actuator, and the upper one contains the entrance and exit holes of the fluid, so that the flow rate of the fluid flow depends on the position of the membrane or shutter defined in the wafer intermediate.

Esencialmente se ha previsto que entre la oblea inferior y el obturador de la oblea intermedia se establezca una cámara estanca, dotada de un orificio de entrada de gas a presión, de manera que a través de dicho orificio puede suministrarse a la citada cámara una presión próxima y ligeramente superior a la presión de entrada del fluido a controlar, con lo que el esfuerzo a realizar por el medio actuador es mínimo, al encontrarse las citadas presiones próximas a la situación de compensación.Essentially it is expected that between the wafer bottom and the intermediate wafer shutter set a watertight chamber, equipped with a pressurized gas inlet hole, so that through this hole it can be supplied to the said chamber a pressure close to and slightly higher than the fluid inlet pressure to be controlled, so that the effort to perform by the actuator means is minimal, to meet those mentioned pressures close to the compensation situation.

De esta manera se consigue un fácil accionamiento de la membrana u obturador, con independencia de la presión del fluido a controlar y por muy alta que esta sea, con un consumo energético mínimo por parte de dicho accionador.In this way an easy drive is achieved of the membrane or plug, regardless of the pressure of the fluid to control and no matter how high, with a consumption minimum energy by said actuator.

La válvula puede ser simple o múltiple, de manera que en este último caso una oblea inferior única con una pluralidad de cámaras debidamente interconectadas entre sí y a una fuente de presión única, actúa simultáneamente sobre las membranas u obturadores de las diferentes válvulas.The valve can be single or multiple, so that in the latter case a single lower wafer with a plurality of cameras properly interconnected with each other and to a source of single pressure, acts simultaneously on the membranes or shutters of the different valves.

Descripción de los dibujosDescription of the drawings

Para complementar la descripción que se está realizando y con objeto de ayudar a una mejor comprensión de las características del invento, de acuerdo con un ejemplo preferente de realización práctica del mismo, se acompaña como parte integrante de dicha descripción, un juego de dibujos en donde con carácter ilustrativo y no limitativo, se ha representado lo siguiente:To complement the description that is being performing and in order to help a better understanding of the characteristics of the invention, according to a preferred example of practical realization of it, is accompanied as part member of that description, a set of drawings where with illustrative and non-limiting nature, what has been represented next:

La figura 1.- Muestra una representación esquemática en alzado lateral y en sección de una válvula microfluídica para alta presión realizada de acuerdo con el objeto de la presente invención.Figure 1.- Shows a representation schematic side elevation and section of a valve microfluidic for high pressure performed according to the object of the present invention.

La figura 2.- Muestra, según una representación similar a la de la figura 1, una variante de realización en la que la válvula es múltiple.Figure 2.- Shows, according to a representation similar to that of figure 1, a variant embodiment in which The valve is multiple.

Realización preferente de la invenciónPreferred Embodiment of the Invention

A la vista de las figuras reseñadas y especialmente de la figura 1, puede observarse como la válvula que se preconiza está constituida mediante tres obleas (1), (2) y (3), rígida y herméticamente unidas entre sí por cualquier procedimiento convencional adecuado, como puede ser mediante unión anódica, soldado químico, juntas de estanqueidad o cualquier otro medio que le garantice dicha estanqueidad.In view of the figures outlined and especially from figure 1, it can be seen as the valve that It is recommended to be constituted by three wafers (1), (2) and (3), rigid and tightly joined together by any procedure conventional suitable, such as by anodic bonding, chemical soldier, gaskets or any other means that I guarantee this tightness.

La oblea intermedia (2) está afectada en su cara enfrentada a la oblea intermedia (1) por un amplio rebaje (4), que en el ejemplo de realización práctica de la citada figura 1 adopta una configuración tronco-cónica, pero que puede adoptar cualquier otra configuración apropiada sin que ello afecte a la esencia de la invención, rebaje de profundidad en el mismo para que en el fondo se establezca una membrana (5) de espesor suficientemente reducido como para resultar fácilmente deformable.The intermediate wafer (2) is affected on your face faced with the intermediate wafer (1) by a wide recess (4), which in the practical example of the aforementioned figure 1 adopts a conical trunk configuration, but that can adopt any other appropriate configuration without affecting the essence of the invention, depth reduction in it for that at the bottom a membrane (5) thick is established small enough to be easily deformable

Este rebaje (4) puede estar obtenido mediante una operación de dopado, complementada con un ataque anisotrópico por su otra cara, que rebaja el espesor de la oblea de esta zona hasta las dimensiones idóneas, de tan sólo unas micras, frente a los cientos de micras que dicha membrana u obturador (5) puede presentar de diámetro.This recess (4) can be obtained by means of a doping operation, complemented by an anisotropic attack by its other side, which reduces the wafer thickness of this area until the ideal dimensions, of only a few microns, compared to hundreds of microns that said membrane or obturator (5) can present in diameter.

El rebaje (4) de la oblea intermedia (2) tiene como finalidad complementaria establecer entre estas dos obleas una cámara (6), comunicada con el exterior a través de un orificio (7), para suministrar a dicha cámara (6) una presión predeterminada, que a su vez será suministrada a la membrana u obturador (5).The recess (4) of the intermediate wafer (2) has as a complementary purpose to establish between these two wafers a chamber (6), communicated with the outside through a hole (7), to supply said chamber (6) with a predetermined pressure, which in turn it will be supplied to the membrane or obturator (5).

Complementariamente se ha previsto que la oblea inferior (1) presente en su zona de enfrentamiento al rebaje (4) una protuberancia (8) en la que se establece el medio actuador (9), como por ejemplo un electrodo, en orden a que este resulte suficientemente próximo a la membrana (5), para poder actuar fácilmente sobre la misma.In addition, it is expected that the wafer lower (1) present in its zone of confrontation with the recess (4) a protuberance (8) in which the actuator means (9) is established, such as an electrode, in order for it to be close enough to the membrane (5), to act easily on it.

Como complemento de la estructura descrita la oblea superior (3) contará con al menos un orificio de entrada (10) para el fluido a controlar, y uno o varios orificios de salida (11) para dicho fluido, de manera que la membrana (5) cierra todos estos orificios en situación de cierre valvular, al presionar contra la cara interna de la oblea (3), y los pone en comunicación cuando sufre una deformación al ser arrastrada por el mecanismo actuador (9).As a complement to the structure described, the upper wafer (3) will have at least one inlet hole (10) for the fluid to be controlled, and one or more outlet holes (11) for said fluid, so that the membrane (5) closes all these holes in valve closure situation, when pressed against the internal face of the wafer (3), and puts them in communication when undergoes a deformation when dragged by the actuator mechanism (9).

La oblea inferior (3), en funciones de soporte para la válvula en su conjunto, estará obtenida a base de un material rígido tal como metal, silicio u otro, la oblea intermedia (2) podrá ser de la misma naturaleza, y la oblea superior (3), también de naturaleza rígida podrá ser de vidrio, silicio u otro material de prestaciones similares.The bottom wafer (3), in support functions for the valve as a whole, it will be obtained based on a rigid material such as metal, silicon or other, the intermediate wafer (2) may be of the same nature, and the upper wafer (3), also of a rigid nature may be glass, silicon or other Similar performance material.

De acuerdo con esta estructuración, el funcionamiento de la válvula es el siguiente:According to this structuring, the Valve operation is as follows:

Teniendo en cuenta que el fluido a controlar suministra al orificio de entrada (10) una presión P1, a la cámara (6) y a través de su orificio de entrada (7) se suministra una presión P2 mayor que la citada presión P1 con lo que la válvula se mantendrá permanentemente cerrada, independientemente de la tensión que se aplique al elemento actuador (9) que será insuficiente para vencer la diferencia entre las presiones P2 y P1. Sin embargo si a la cámara (6) se aplica una presión P2 ligeramente superior a la presión P1 del fluido a controlar, la fuerza que produzca el actuador (9), por ejemplo un actuador electrostático, será suficiente para variar la posición de la membrana (5), abriendo la válvula.Taking into account that the fluid to be controlled supplies the inlet port (10) with a pressure P1, to the chamber (6) and through its entrance hole (7) a pressure P2 greater than the mentioned pressure P1 so that the valve is will keep permanently closed, regardless of tension that is applied to the actuator element (9) that will be insufficient to overcome the difference between pressures P2 and P1. However, if the chamber (6) applies a pressure P2 slightly higher than the P1 pressure of the fluid to be controlled, the force produced by the actuator (9), for example an electrostatic actuator, will be enough to vary the position of the membrane (5), opening the valve.

No obstante, la fuerza electrostática del actuador (9) sólo debe vencer la fuerza debida a la diferencia de presiones, con lo que la potencia de dicho actuador es mínima, y mínimo también su consumo de energía, a pesar de que la válvula esté trabajando con presiones P1 muy elevadas, del orden de decenas de atmósferas.However, the electrostatic force of actuator (9) must only overcome the force due to the difference in pressures, so that the power of said actuator is minimal, and also minimizes its energy consumption, despite the fact that the valve is working with very high P1 pressures, of the order of tens of atmospheres

Esta estructuración valvular permite, complementariamente, utilizar la presión de la cámara (6) como medio de seguridad para cerrar la válvula instantáneamente, con independencia de la tensión de control, en el caso de que esto sea necesario.This valve structuring allows, in addition, use chamber pressure (6) as safety means to close the valve instantly, with independence of the control voltage, in case this is necessary.

La válvula presenta básicamente dos estados de equilibrio, completamente abierta y completamente cerrada, pero puede usarse también para regular el caudal mediante la sucesión adecuada de intervalos de apertura y cierre.The valve basically has two states of balance, completely open and completely closed, but can also be used to regulate the flow rate through succession adequate opening and closing intervals.

En cualquiera de los dos estados de reposo el consumo energético de la válvula es teóricamente nulo, produciéndose el consumo sólo durante la conmutación, lo que equivale que en el funcionamiento normal de la válvula el consumo total de la misma sea muy reducido, como ya se ha apuntado con anterioridad.In either of the two resting states the The energy consumption of the valve is theoretically zero, the consumption occurring only during switching, which equivalent to the normal operation of the valve consumption Total of it is very small, as already noted with anteriority.

Finalmente y de acuerdo con la representación de la figura 2, es factible confeccionar una válvula múltiple, concretamente una válvula doble en el ejemplo de dicha figura, en la que sobre una oblea inferior (1') se establezcan varias cámaras (6), (6')..., correspondientes a respectivas unidades valvulares, con idéntica estructuración que en el caso anterior, pero en este caso con la salvedad de que las diferentes cámaras (6), (6') estarán relacionadas entre sí mediante canalizaciones de comunicación (12) que permiten establecer la misma presión en todas las cámaras (6), (6') a partir de una fuente de alimentación única.Finally and in accordance with the representation of Figure 2, it is feasible to make a multiple valve, specifically a double valve in the example of said figure, in which on a lower wafer (1 ') several chambers are established (6), (6 ') ..., corresponding to respective valve units, with identical structuring as in the previous case, but in this case with the proviso that the different cameras (6), (6 ') will be related to each other through pipes communication (12) that allow to establish the same pressure in all the cameras (6), (6 ') from a power supply only.

Claims (4)

1. Válvula microfluídica para alta presión, caracterizada por estar constituida por tres obleas rígida y estancamente unidas entre sí, una oblea inferior (1) en función de soporte del conjunto, una oblea intermedia (2) dotada de un profundo rebaje (4) determinante de una membrana u obturador (5) de reducido espesor, y una oblea superior (3) que, en situación de enfrentamiento a la membrana (5), incorpora al menos un orificio (10) de entrada del fluido a controlar y uno o más orificios de salida (11) para dicho fluido, habiéndose previsto que entre la oblea intermedia (2) y la oblea inferior (1) se defina una cámara (6) dotada de al menos un orificio de presurización (7), en orden a que la presión P2 en dicha cámara (6) sea sensiblemente próxima a la alta presión P1 existente en el orificio (10) de entrada del fluido a controlar.1. Microfluidic valve for high pressure, characterized by being constituted by three rigid wafers and tightly joined together, a lower wafer (1) depending on the support of the assembly, an intermediate wafer (2) equipped with a deep recess (4) determining of a membrane or obturator (5) of reduced thickness, and an upper wafer (3) which, in a situation of confrontation with the membrane (5), incorporates at least one orifice (10) of fluid inlet to be controlled and one or more exit holes (11) for said fluid, it being provided that between the intermediate wafer (2) and the lower wafer (1) a chamber (6) is provided with at least one pressurization hole (7), in order to the pressure P2 in said chamber (6) is substantially close to the high pressure P1 in the inlet port (10) of the fluid to be controlled. 2. Válvula microfluídica para alta presión, según reivindicación 1, caracterizada porque la oblea inferior (1) presenta, en su zona de enfrentamiento al rebaje (4) de la oblea intermedia (2), una protuberancia (8) sobre la que se sitúa el medio actuador valvular (9), en orden a que este quede sustancialmente próximo a la membrana u obturador (5).2. Microfluidic valve for high pressure, according to claim 1, characterized in that the lower wafer (1) has, in its area of recess (4) of the intermediate wafer (2), a protuberance (8) on which it is located the valve actuator means (9), in order that it is substantially close to the membrane or plug (5). 3. Válvula microfluídica para alta presión, según reivindicaciones anteriores, caracterizada porque las obleas (1), (2) y (3) son de un material rígido, como por ejemplo metal, silicio, vidrio u otro.3. Microfluidic valve for high pressure, according to previous claims, characterized in that the wafers (1), (2) and (3) are made of a rigid material, such as metal, silicon, glass or other. 4. Válvula microfluídica para alta presión, según reivindicaciones anteriores, caracterizada porque sobre una misma oblea inferior (1), con una estructura repetitiva, se establecen varias obleas intermedias (2) y obleas superiores (3) para configurar una válvula múltiple, en la que las cámaras de presión (6), (6'), ..., se encuentran comunicadas entre sí para actuar simultáneamente sobre todas ellas.4. Microfluidic valve for high pressure, according to previous claims, characterized in that on the same lower wafer (1), with a repetitive structure, several intermediate wafers (2) and upper wafers (3) are established to configure a multiple valve, in the that the pressure chambers (6), (6 '), ..., are communicated with each other to act simultaneously on all of them.
ES200102361A 2001-10-23 2001-10-23 MICROFLUIDIC VALVE FOR HIGH PRESSURE. Expired - Fee Related ES2229829B1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
ES200102361A ES2229829B1 (en) 2001-10-23 2001-10-23 MICROFLUIDIC VALVE FOR HIGH PRESSURE.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES200102361A ES2229829B1 (en) 2001-10-23 2001-10-23 MICROFLUIDIC VALVE FOR HIGH PRESSURE.

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ES2229829A1 true ES2229829A1 (en) 2005-04-16
ES2229829B1 ES2229829B1 (en) 2006-07-01

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10369579B1 (en) 2018-09-04 2019-08-06 Zyxogen, Llc Multi-orifice nozzle for droplet atomization

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4581624A (en) * 1984-03-01 1986-04-08 Allied Corporation Microminiature semiconductor valve
US5029805A (en) * 1988-04-27 1991-07-09 Dragerwerk Aktiengesellschaft Valve arrangement of microstructured components
JPH04126324A (en) * 1990-09-17 1992-04-27 Seiko Epson Corp Fluid controller and its manufacture
WO2001036851A1 (en) * 1999-11-18 2001-05-25 Asahi Organic Chemicals Industry Co., Ltd. Constant pressure regulator

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4581624A (en) * 1984-03-01 1986-04-08 Allied Corporation Microminiature semiconductor valve
US5029805A (en) * 1988-04-27 1991-07-09 Dragerwerk Aktiengesellschaft Valve arrangement of microstructured components
JPH04126324A (en) * 1990-09-17 1992-04-27 Seiko Epson Corp Fluid controller and its manufacture
WO2001036851A1 (en) * 1999-11-18 2001-05-25 Asahi Organic Chemicals Industry Co., Ltd. Constant pressure regulator

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10369579B1 (en) 2018-09-04 2019-08-06 Zyxogen, Llc Multi-orifice nozzle for droplet atomization

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